Gene Information

Name : BAA_2893 (BAA_2893)
Accession : YP_002867104.1
Strain : Bacillus anthracis A0248
Genome accession: NC_012659
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase (NAD) family protein
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.-
Position : 2626424 - 2627908 bp
Length : 1485 bp
Strand : -
Note : identified by match to protein family HMM PF00171

DNA sequence :
ATGTTAACGACAAATATTGAGTTGAAACCAAAAGTGAAAGCGTTTTTAGATGAAGAGATTAAAATGTTTATTAATGGTGA
ATTTGTTCCTTCTATTAGTGGAAAGACGTTTGAAACATATAATCCAGCAACAGAAGATGTTCTTGCAGTTGTTTATGAAG
CACAAGAAGAGGATATTGATGTGGCAGTAAAAGCGGCGAGATCTGCATTTGAATCAGGACCTTGGGTGGAAATGACTACT
GCTGAAAGAGCACATCTTATTTATAAATTAGCAGACTTAATTGAAGAGCATGGAGAAGAATTAGCACAGCTAGAAGCTTT
AGATAATGGAAAACCATATCAAGTAGCACTTGATGATGATATTGCAGCGACTGTAGAAAATTATCGCTATTATGCAGGAT
GGGCTACAAAAATTATCGGGCAAACCATTCCGATTTCAAAAGATTACTTAAATTACACACGCCATGAACCTGTTGGCGTT
GTAGGGCAAATTATTCCTTGGAATTTTCCGCTCGTTATGTCTTCTTGGAAAATGGGAGCTGCGCTAGCAACAGGTTGTAC
GATCGTATTAAAACCAGCAGAACAAACTCCTTTATCTTTATTATATACAGCGAAGCTCTTTAAAGAGGCTGGTTTTCCAA
ACGGTGTTGTAAACTTTGTTCCAGGGTTTGGTCCTGAAGCAGGAGCTGCAATTGTAAACCATCATGATATTGATAAAGTA
GCCTTTACGGGTTCAACAGTTACTGGAAAATATATTATGCGTCAATCTGCAGAAACAATTAAACATGTAACGTTAGAACT
GGGTGGTAAATCACCAAATATCATTTTAGAAGACGCTGATTTAGAAGAAGCGATTAACGGTGCATTCCAAGGTATTATGT
ATAATCACGGTCAAAATTGTAGTGCTGGATCTCGCGTGTTCGTTCACCGAAAACATTACGAAACAGTCGTAAATGAACTT
GTGAAAATGGCGAATAACGTGAAACTTGGAGCAGGTATGGAGAAGGACACGGAAATGGGTCCACTCGTATCTAAAAAGCA
ACAAGAGCGTGTGCTACATTACATTGAACAAGGAAAAGCTGAAGGCGCTACTGTTGCTGCTGGTGGTGAACGTGCATTTG
AAAAAGGTTATTTTGTACAGCCAACAGTATTCACAGATGTTACGGACGATATGACGATAGTTAAGGAAGAAATCTTCGGT
CCTGTTGTCGTTGTACTTCCATTTGATTCGACGGAAGAAGTAATTGAAAGAGCAAATCGTTCGTCATATGGACTTGCAGC
GGGCGTATGGACACAAAATATTAAAACAGGACATCAAGTTGCCAATAAGTTAAAGGCAGGAACAGTATGGATTAATGATT
ATAACTTAGAAAATGCAGCGGCACCATTTGGTGGGTTTAAACAATCTGGTATCGGCCGTGAGTTAGGTTCATATGCACTT
GATAATTACACAGAAGTGAAAAGTGTTTGGGTAAATATAAAGTAA

Protein sequence :
MLTTNIELKPKVKAFLDEEIKMFINGEFVPSISGKTFETYNPATEDVLAVVYEAQEEDIDVAVKAARSAFESGPWVEMTT
AERAHLIYKLADLIEEHGEELAQLEALDNGKPYQVALDDDIAATVENYRYYAGWATKIIGQTIPISKDYLNYTRHEPVGV
VGQIIPWNFPLVMSSWKMGAALATGCTIVLKPAEQTPLSLLYTAKLFKEAGFPNGVVNFVPGFGPEAGAAIVNHHDIDKV
AFTGSTVTGKYIMRQSAETIKHVTLELGGKSPNIILEDADLEEAINGAFQGIMYNHGQNCSAGSRVFVHRKHYETVVNEL
VKMANNVKLGAGMEKDTEMGPLVSKKQQERVLHYIEQGKAEGATVAAGGERAFEKGYFVQPTVFTDVTDDMTIVKEEIFG
PVVVVLPFDSTEEVIERANRSSYGLAAGVWTQNIKTGHQVANKLKAGTVWINDYNLENAAAPFGGFKQSGIGRELGSYAL
DNYTEVKSVWVNIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 2e-88 44
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-85 41
hpaE AAO17179.1 HpaE Not tested tcd island Protein 4e-79 41
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 1e-86 41
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 1e-86 41
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 1e-86 41
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 4e-86 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BAA_2893 YP_002867104.1 aldehyde dehydrogenase (NAD) family protein VFG0082 Protein 4e-86 41