Gene Information

Name : clpB (CLJ_B0468)
Accession : YP_002861284.1
Strain : Clostridium botulinum 657
Genome accession: NC_012658
Putative virulence/resistance : Virulence
Product : clpB protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 482313 - 484913 bp
Length : 2601 bp
Strand : +
Note : identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR03346

DNA sequence :
ATGGATATTGAAAAATTAACTTTAAAGGTACAGCAAGCTATAAATGATTCTCAACTTGTTGCAGTTAAGTATAATCATCA
GCAGATTGATACTATACATTTATTTTCAGCCTTAATTTCTCAAGATGATGGATTAATTCATAATATTTTAGGGAAAATGG
GAGTGAATATAAGAGATATTAATGCTGAAACCAATATGGTTTTAGATAATATGCCTAAAGTATTAGGTGAGGGAGCACAG
TCCTCTTCTGTGTATCCTACTAGAAGGTTCGAAGAGGTTTTTGTAAAGGCGGAACAGATAGCAAAGGATTTTAAAGATTC
ATATATAAGTGTAGAACATGTTTTATTAGCTATAATGGATGTGGATAAAAATAATGTTTATCCTATATTAGAAAAATTTG
GAGTGAAAAAATCAGAATTTTTAAAGGCATTATCAGCTGTTAGAGGAAGTCAAAGAGTTGATAGTCAAGATCCAGAGGGG
ACTTATGAAGCTTTGGTTAAGTATGGTAGAAATTTAGTTGAAGAAGCTAAGAAACATAAATTGGATCCTGTTATAGGTAG
AGATGAAGAAATAAGAAGAGTTGTAAGAATTTTATCTAGAAGAACTAAAAATAATCCTGTTCTTATCGGAGAACCAGGTG
TAGGTAAGACTGCTATTGTAGAGGGATTAGCAGAGAGAATTGTTAGAGGAGATGTACCAGAAAGTTTAAAAAATAAAATA
ATATTTTCTTTAGATATGGGGGCACTTATTGCAGGTGCAAAATATAGAGGAGAATTTGAAGAAAGATTAAAAGCAGTATT
AAAGGAAGTTCAAAATAGTGAGGGAAGGATAATTTTATTTATAGATGAAATCCATACTATAGTAGGTGCAGGAAAAACAG
AGGGATCTATGGATGCAGGGAATTTGATAAAACCTATGCTTGCTAGAGGAGAACTTCATTGTATTGGAGCTACTACCTTT
GATGAATATAGACAGTATATAGAAAAAGACAAAGCTTTAGAAAGAAGATTTCAACCTGTAATAACAGATGAGCCTACAGT
AGAGGATACAGTATCTATATTAAGAGGGCTTAAAGAAAGATTTGAAATATATCATGGAATAAGAATACATGATTCAGCTA
TTGTAGCTGCAGCTAAGCTCTCTAGTAGATATATTACAGATAGATATCTCCCAGACAAAGCAATAGATTTAATAGATGAA
GCTTGTGCTATGATAAGAACAGATATAGATAGTATGCCAACGGAAATGGATTCAATGAAAAGAAAAATATTTCAATTAGA
AATAGAAAAGGAAGCATTGTCTAAAGAAAAAGATGTGGCTTCAAAGGAAAGATTAGAAGTTTTAGAAAAGGAATTGAGTG
AACTAAAAGAGAAAGATAAAGAAATGACAGCCAAGTATGAAAATGAAAAATCTCATATAACAAAAATAAGAGATTTAAAA
GAAAAATTGGATGATGTTAGAGGTCAGATGGAAAAGGCCGAAAGAGAATATGATTTGAATAAAGTTGCAGAATTAAAATA
TGGTTTAATACCAGCTCTTCAAAGAGAAATAGAAGAAAAAGAAAAATTAATAAAGGAAAATAGTAACGGAAATGCTATGT
TAAAAGAAGAGGTTACAGAGCAGGAAATTTCTGAAATAATCTCTAAATGGACTGGTATACCTGTAACAAGATTAGTTGAA
ACTGAAAGACAAAAACTATTACAATTAGGAGATCAATTAGAAGCTAGAGTAATAGGTCAAGGAGAGGCAGTAAAAGCAGT
AACTAATGCAGTTATAAGAGCTAGAGCAGGACTAAAAGATCCAAGAAAACCTATAGGATCATTTATATTCTTAGGACCTA
CAGGTGTAGGAAAGACAGAACTTGCAAAAACTTTGGCTAGAACTTTATTTGATACTGAAGAAAATATTATAAGAATAGAT
ATGTCTGAATATATGGAAAAATATTCAGTATCAAGACTTATAGGAGCCCCTCCAGGATATGTAGGATATGAAGAAGGGGG
TCAGCTAACAGAAGCCGTTAGGAGAAAACCTTATAGTGTTATATTGTTTGATGAAATAGAAAAAGCTCATGACGATGTAT
TTAACATATTCCTTCAAATATTAGATGATGGAAGACTTACAGACAATAAGGGGAAGGTTATAGATTTTAAAAATACTATA
ATTATAATGACTTCTAATTTGGGAAGTAACTATTTATTAGATAATGAAAGCAAAGAAGGCATAGATGAAAGTATAAGAAC
AAGAGTAAAAGAGGCTTTAAAAGCTAGATTTAAACCAGAATTTTTAAATAGAGTAGATGATATTATAATGTTTAAACCTC
TTACGGTAGAAGACATTAAGAGAATAATAGATATATTCTTAGATGATATAAGAAAAAGACTTAAAGATAAGAATATACAG
CTTAAAATTACTGATAGTGCAAAAGATATAATGGCCAAAGAAGGTTATGATCCAATATATGGCGCAAGACCGCTAAAGAG
ATATATAGAAGATACTATAGAAACAGAAATAGCAAAACAAATAATAGCAGGTAACATATATGAAGGTACTACTGTAGGGG
TAGACTTAAAAGGGGAGTCAATAGTTATAGAAAGAATATAA

Protein sequence :
MDIEKLTLKVQQAINDSQLVAVKYNHQQIDTIHLFSALISQDDGLIHNILGKMGVNIRDINAETNMVLDNMPKVLGEGAQ
SSSVYPTRRFEEVFVKAEQIAKDFKDSYISVEHVLLAIMDVDKNNVYPILEKFGVKKSEFLKALSAVRGSQRVDSQDPEG
TYEALVKYGRNLVEEAKKHKLDPVIGRDEEIRRVVRILSRRTKNNPVLIGEPGVGKTAIVEGLAERIVRGDVPESLKNKI
IFSLDMGALIAGAKYRGEFEERLKAVLKEVQNSEGRIILFIDEIHTIVGAGKTEGSMDAGNLIKPMLARGELHCIGATTF
DEYRQYIEKDKALERRFQPVITDEPTVEDTVSILRGLKERFEIYHGIRIHDSAIVAAAKLSSRYITDRYLPDKAIDLIDE
ACAMIRTDIDSMPTEMDSMKRKIFQLEIEKEALSKEKDVASKERLEVLEKELSELKEKDKEMTAKYENEKSHITKIRDLK
EKLDDVRGQMEKAEREYDLNKVAELKYGLIPALQREIEEKEKLIKENSNGNAMLKEEVTEQEISEIISKWTGIPVTRLVE
TERQKLLQLGDQLEARVIGQGEAVKAVTNAVIRARAGLKDPRKPIGSFIFLGPTGVGKTELAKTLARTLFDTEENIIRID
MSEYMEKYSVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSVILFDEIEKAHDDVFNIFLQILDDGRLTDNKGKVIDFKNTI
IIMTSNLGSNYLLDNESKEGIDESIRTRVKEALKARFKPEFLNRVDDIIMFKPLTVEDIKRIIDIFLDDIRKRLKDKNIQ
LKITDSAKDIMAKEGYDPIYGARPLKRYIEDTIETEIAKQIIAGNIYEGTTVGVDLKGESIVIERI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 6e-168 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_002861284.1 clpB protein VFG2084 Protein 4e-103 41