Gene Information

Name : dnaB (CLJ_B3959)
Accession : YP_002864629.1
Strain : Clostridium botulinum 657
Genome accession: NC_012658
Putative virulence/resistance : Unknown
Product : replicative DNA helicase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0305
EC number : 3.6.1.-
Position : 3953692 - 3955026 bp
Length : 1335 bp
Strand : -
Note : unwinds double stranded DNA

DNA sequence :
ATGGATGCACCCATAAAAAGTATGCCGCAGAGTATAGATGCAGAGCAAAATGTATTAGGGGCAATGATTATAGATAAAAC
TTCCATAGCAGAGGCTGTGGAAGTTTTAAAAAGTGAAGATTTTTATAAAGATTCTCATAAAATTATATTTAGTGGAATTA
TAGAGCTTTATCAAAAGGATATAGCAGTAGATATGCTAACTCTTACGGAAAATCTTAAGTCACGAGATAAACTAGAGGCA
GTAGGTGGGGTTACTTATATAACAGAGCTTTGTAACTCTATAGTTTCTACAGCTAATATTCAGTCTTATATAGATATAAT
AAAGGATAAATCTACATTAAGAAGGCTTATAAAGTCATCTACTGAAATAATAGAGAACTGTTATAACAGACAGGATAATG
TAGAAGAAATAATAGATTCTGCAGAGAAAAAAATATTTCACATATCCAACCAAAATACTACAACTGATTTTGAACCATTA
AGTAATGTTTTGGAAAGAGGATTTATTCAAATTGAAAACTTATTTAAAAATAAAGGTGAAACTACAGGGGTTGCATCTGG
TTTTAGAGAACTAGACGCTAAAACCTCAGGTTTTCAAAAGTCTGATATGATATTAATAGCAGCAAGACCATCAATGGGTA
AAACTACATTTGCTCTAAACATAGCAGAATATGCAGCTCTTAGAGAGGGAAAAAGTGTAGCAATCTTTTCCCTGGAAATG
TCAAAAGAGCAACTTTCTTATAAACTGCTTTGTTCACAAGCTAATATTGATATGTTGAGACTTAGAACTGGTAACTTAGA
GGACAAAGATTGGGAGAATATAGCTAGGGTTTCAGGGCCTTTAGCAGCAGCAAAGATATTTATAGATGATACTGCAGGTA
TGTCTGTAATGGAAATGCGTTCTAAATGTAGGAGATTAAAGATAGAACATGGAATAGATATGGTTTTAATAGATTATCTT
CAGCTTATGAGCGGAGGTAAAGGTTCTGAAAGCAGACAACAAGAAGTTTCAGAAATATCTAGATCTATAAAAGCCTTAGC
AAAAGAAATGGATTGTCCAGTTATAGCCCTGTCACAATTATCTCGTGCTCCGGAGGCTAGATCAGATCATAGACCAATGC
TTTCAGATCTTAGAGAATCTGGATCTATAGAACAGGACGCTGACGTAGTTATGTTTTTATATAGGGATGAATATTATGAT
AAAGAAACAGAAGATAAAAACATGGCAGAATGCATTATAGCCAAGCAAAGAAATGGTCCTACAGGTACAGTTAAATTGGC
ATGGCTTGGACAGTACAGTAAATTTGGCAATTTAGATGTAATACATCAAGAATAA

Protein sequence :
MDAPIKSMPQSIDAEQNVLGAMIIDKTSIAEAVEVLKSEDFYKDSHKIIFSGIIELYQKDIAVDMLTLTENLKSRDKLEA
VGGVTYITELCNSIVSTANIQSYIDIIKDKSTLRRLIKSSTEIIENCYNRQDNVEEIIDSAEKKIFHISNQNTTTDFEPL
SNVLERGFIQIENLFKNKGETTGVASGFRELDAKTSGFQKSDMILIAARPSMGKTTFALNIAEYAALREGKSVAIFSLEM
SKEQLSYKLLCSQANIDMLRLRTGNLEDKDWENIARVSGPLAAAKIFIDDTAGMSVMEMRSKCRRLKIEHGIDMVLIDYL
QLMSGGKGSESRQQEVSEISRSIKALAKEMDCPVIALSQLSRAPEARSDHRPMLSDLRESGSIEQDADVVMFLYRDEYYD
KETEDKNMAECIIAKQRNGPTGTVKLAWLGQYSKFGNLDVIHQE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
t4227 NP_807829.1 DNA helicase Not tested SPI-7 Protein 5e-73 43
STY4522 NP_458617.1 DNA helicase Not tested SPI-7 Protein 5e-73 43
unnamed ABR13456.1 replicative DNA helicase Not tested PAGI-5 Protein 6e-84 42
dnaB2 YP_001007676.1 putative DNA helicase Not tested YAPI Protein 1e-79 42
dnaB2 YP_001402701.1 replicative DNA helicase Not tested YAPI Protein 2e-80 42
api2 CAF28476.1 putative DNA binding protein with DNA-dependent ATPase activity Not tested YAPI Protein 6e-81 42
PMI2640 YP_002152342.1 DNA helicase Not tested Not named Protein 6e-75 41