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Name : guaA (CLJ_B3575) Accession : YP_002864287.1 Strain : Clostridium botulinum 657 Genome accession: NC_012658 Putative virulence/resistance : Unknown Product : GMP synthase Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0519 EC number : 6.3.5.2 Position : 3575068 - 3576600 bp Length : 1533 bp Strand : - Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway DNA sequence : ATGAATAAAGAATTAGTATTAGTAGTTGACTTTGGAGGTCAATATAATCAGTTAATAGCAAGACGTGTAAGGGAAAATAG AGTGTATTGTGAAATAGTACCTTATACTACTTCTATAGAAGATATAAAAGAAAAAGCACCAAAGGGAATAATATTTACAG GTGGTCCTAATAGTGTATATGGAGAAAATGCACCAAGAGTTCAAAAAGAATTATTTGATTTAGGTATTCCAGTCTTAGGT ATATGTTATGGAGATCAACTTATGGCACATAGCTTAGAAGGTGAAGTAACAAGTCCTGAAAAAAGAGAATATGGTAAAAC AGATGTAAATTTAGATAATAGTAGTTTATTGTTTAAGGATATGAAAGAGAAAGATCAATGCTGGATGAGTCATACAGATT ATATTTCAAAGGTTCCAAAAGGATTTAAAATTATAGCAACAACAGATGAGTGCCCTTGTGCAGCTATGGAAAATGCGGAA AAAAAATTATATGGAGTTCAATTTCATCCAGAGGTAGAGCATACTTTATTTGGCAAAAAAATGCTTAAAAACTTTTTGTT TAACGTATGTAATTTAAAAGGTGATTGGACTATGAGTTCTTTTGCAGAGCAGCAAATAAAAGCTATAAAGGAAAAAGTAG GAAATAAAAAAGTAATATGCGCTCTATCAGGTGGAGTAGATTCATCAGTAGCAGCAGTAATTGTTCATAAAGCTATAGGG AAACAATTAACTTGTATATTTGTTGATCATGGTTTACTTAGAAAAGATGAAGGAGATCAAGTAGAAAAAATATTTAAAGA TCAATTTGATATGAATTTAATAAGAGTTAATGCTCAAGATAGATTTTTAGGAAAATTAAAAGGAGTTTCAGATCCAGAAA GAAAAAGAAAAATAATTGGAGAAGAATTTATAAGAGTATTTGAAGAAGAAGCTAAAAAATTAGGTGATATAAGTTTCTTA GTTCAAGGTACCATATATCCTGATATAGTAGAAAGTGGAACAAACACATCAGCTACTATAAAAAGCCACCACAATGTAGG TGGGCTGCCAGAAGACATGGAATTTAAATTAATAGAACCTTTAAGAGAATTGTTTAAAGATGAAGTAAGAGCTGTTGGAG AAGAATTAGGTATACCACATAAATTAGTATGGAGACAGCCATTCCCAGGACCAGGTTTAGCTATAAGAGTATTAGGTGAG GTTACAGAGGAAAAATTAGCTATTACAAGAGAAGCAGATGCTATATTCAGAGAAGAGATAGCTAAAGCAGGCTTAGAAGA AAAAATATGGCAATATTTTGCTTGCCTTCCAAACATACAATCAGTAGGAGTAATGGGAGATGAAAGAACATATTGCCATA CAATAGCATTAAGAGCTGTTACATCTTCAGATGCGATGACTTCAGATTGGGCAAGAATACCTTATGAAGTATTAGATAAA GTATCAAGAAGAATAGTAAATGAGGTTAAAGAAGTAAACAGAATCGTGTATGATGTAACTTCAAAACCACCAGCAACTAT TGAATGGGAATAA Protein sequence : MNKELVLVVDFGGQYNQLIARRVRENRVYCEIVPYTTSIEDIKEKAPKGIIFTGGPNSVYGENAPRVQKELFDLGIPVLG ICYGDQLMAHSLEGEVTSPEKREYGKTDVNLDNSSLLFKDMKEKDQCWMSHTDYISKVPKGFKIIATTDECPCAAMENAE KKLYGVQFHPEVEHTLFGKKMLKNFLFNVCNLKGDWTMSSFAEQQIKAIKEKVGNKKVICALSGGVDSSVAAVIVHKAIG KQLTCIFVDHGLLRKDEGDQVEKIFKDQFDMNLIRVNAQDRFLGKLKGVSDPERKRKIIGEEFIRVFEEEAKKLGDISFL VQGTIYPDIVESGTNTSATIKSHHNVGGLPEDMEFKLIEPLRELFKDEVRAVGEELGIPHKLVWRQPFPGPGLAIRVLGE VTEEKLAITREADAIFREEIAKAGLEEKIWQYFACLPNIQSVGVMGDERTYCHTIALRAVTSSDAMTSDWARIPYEVLDK VSRRIVNEVKEVNRIVYDVTSKPPATIEWE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| SAMSHR1132_03620 | YP_005324884.1 | GMP synthase | Not tested | vSa¥á | Protein | 8e-162 | 63 |
| guaA | YP_001331415.1 | GMP synthase | Not tested | vSa¥á | Protein | 1e-161 | 63 |
| SAPIG0468 | YP_005733278.1 | GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) | Not tested | SAPI-S0385 | Protein | 9e-162 | 63 |
| guaA | NP_938969.1 | GMP synthase | Not tested | Not named | Protein | 4e-143 | 55 |
