Gene Information

Name : CLJ_B3111 (CLJ_B3111)
Accession : YP_002863867.1
Strain : Clostridium botulinum 657
Genome accession: NC_012658
Putative virulence/resistance : Resistance
Product : chloramphenicol O-acetyltransferase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG4845
EC number : 2.3.1.28
Position : 3111592 - 3112251 bp
Length : 660 bp
Strand : +
Note : identified by match to protein family HMM PF00302

DNA sequence :
ATGAAATTTAATTTAATAGATATTGAACATTGGAACAGAAAGCCATACTTTGAATACTATTTGCATTCTGTTAGGTGTAC
TTATAGCATGACAGCAAATATAGAAATAACAAATTTATTGCATGAAATTAAACTTAAAAAACTTAAACTATATCCAACAC
TTATTTATATCATTGCAACTGTGGTTAATAATCATAAGGAATTTCGCACTTGTTTTGATGAAAACGGTAATTTAGGATAC
TGGGATAGTATGAGTCCGAGTTATACTATCTTTCATAAGGATAACGAAACATTTTCAAGTATCTGGACAGATTATGACGA
AAGCTTTTCATGTTTTTACAATGACTATCTTGATGATATCAAAAACTACGGAGCCATTATGAAGTTTACTCCGAAATTAA
ATGAGCCAGCCAATACATTCCCTGTATCCAGCATCCCTTGGGTGAATTTTACTGGATTTAATCTGAATGTGTACAATAAC
GGAACATATTTAGTTCCTATTTTTACTATGGGCAAATATTTTGAGCAGAATAATAAAATATTTATTCCTATGTCCATACA
GGTGCACCATGCAGTTTGTGATGGTTACCATATCAGCAGATTTATTAATGAGGTACAAGAATTAGCATTAAATTCTCAAA
CATGGTTAAAACATAAATAG

Protein sequence :
MKFNLIDIEHWNRKPYFEYYLHSVRCTYSMTANIEITNLLHEIKLKKLKLYPTLIYIIATVVNNHKEFRTCFDENGNLGY
WDSMSPSYTIFHKDNETFSSIWTDYDESFSCFYNDYLDDIKNYGAIMKFTPKLNEPANTFPVSSIPWVNFTGFNLNVYNN
GTYLVPIFTMGKYFEQNNKIFIPMSIQVHHAVCDGYHISRFINEVQELALNSQTWLKHK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cat YP_006098370.1 chloramphenicol acetyltransferase Not tested Tn2411 Protein 8e-43 45
cat CAJ77070.1 Chloramphenicol acetyltransferase Not tested AbaR1 Protein 5e-43 45
cat AAL08441.1 chloramphenicol acetyltransferase Not tested SRL Protein 6e-43 44
catA2 ACF06176.1 chloramphenicol acetyltransferase II Not tested Tn5036-like Protein 1e-40 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CLJ_B3111 YP_002863867.1 chloramphenicol O-acetyltransferase CP001581.1.gene2168. Protein 1e-64 61
CLJ_B3111 YP_002863867.1 chloramphenicol O-acetyltransferase NC_010111.5787932.p0 Protein 1e-50 48
CLJ_B3111 YP_002863867.1 chloramphenicol O-acetyltransferase NC_010427.6155852.p0 Protein 1e-45 46
CLJ_B3111 YP_002863867.1 chloramphenicol O-acetyltransferase NC_010426.6155849.p0 Protein 1e-45 46
CLJ_B3111 YP_002863867.1 chloramphenicol O-acetyltransferase CP004022.1.gene799.p Protein 5e-44 46
CLJ_B3111 YP_002863867.1 chloramphenicol O-acetyltransferase NC_010558.1.6276004. Protein 3e-43 45
CLJ_B3111 YP_002863867.1 chloramphenicol O-acetyltransferase NC_010410.6002590.p0 Protein 3e-43 45
CLJ_B3111 YP_002863867.1 chloramphenicol O-acetyltransferase NC_011586.7045194.p0 Protein 3e-43 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CLJ_B3111 YP_002863867.1 chloramphenicol O-acetyltransferase VFG1032 Protein 3e-43 44