Gene Information

Name : secA (CLJ_B0217)
Accession : YP_002861043.1
Strain : Clostridium botulinum 657
Genome accession: NC_012658
Putative virulence/resistance : Unknown
Product : preprotein translocase subunit SecA
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG0653
EC number : -
Position : 204582 - 207089 bp
Length : 2508 bp
Strand : +
Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap

DNA sequence :
ATGGGAATTTTAAATAAAATATTTGGTACATATAGTGAAAGAGAACTTAGAAGAGTTAATCCTATAGTAAACAAGATAGA
AGCTTTAGATGAAAAAATGCAATCCTTAAAAGATGAAGATTTTAAGCTAAAAACTGAAGAATTTAAAAGTAGACTAGAAA
AAGGGGAAAAATTAGATGATATCTTACCAGAAGCTTTTGCCTTAGTTAGAGAAGCGGCACATAGAACCATAGGACTTAAA
CATTATAGAGAACAATTAATAGGCGGTGTAGTATTACACCAAGGAAGAATTGGAGAAATGAAAACCGGTGAAGGTAAAAC
TTTAGTTGCTACATTGCCAGCCTATGTAAATGCATTAACAGGAAAAGGGGTACATATAGTTACAGTTAATGATTACTTGG
CAAAAAGAGATAGAGATTTAATGGCTCCGGTATATGAATTTTTAGGGTTAAAAGTAGGAGTTATTTTGCATAATTTAAAT
AATGAAGAAAGACAAGAAGCTTATGGTTCAGATATAACTTATGGAACAAATAGTGAATTTGGTTTTGATTATTTAAGAGA
TAATATGGTAGTTTATAAAGAAGAAAGAGTTCAAAGAAAGTTAAACTTTTCAATTGTGGATGAAGTGGACTCTATATTAA
TAGATGAAGCTAGAACTCCATTAATAATATCAGGTCAAGGGGAGAAGTCTACAGAGTTTTATAAGGTTGCAGATTATTTC
ACTAAATCTCTAATAGCTGAAAAAGATTTTACAATAGATGAAAAAGCTAATTCAGCTATGCTTACAGATGAAGGTGTTAA
TAAGGCAGAGAATTTCTTTAAAGTAGATAACTATGCTGATGCAGAAAACATGGAAATACAACACCATGTAGTTCAAGCTT
TAAAAGCTAACTATGTAATGAAAAAAGATAAAGATTATATGATTAAGGATGGAGAAATTCTAATAGTTGATGAGTTTACA
GGAAGAGCTATGGAAGGAAGAAGATATAGCGATGGATTGCACCAAGCTATAGAAGCTAAAGAAGGCGTTAGAGTAGAAAG
AGAATCTAAAACGTTAGCTACAATAACTTATCAAAACTATTTTAGAATGTACAATAAATTGTCTGGTATGACAGGAACTG
CTCAAACAGAAGAAAATGAATTTAGAGAAATCTATGGATTAGATGTAATTGTAATACCTACACATGAGCCTATAGCAAGA
ATAGATAATGCTGATGTAGTATATAAATCAGAAAAGGGTAAATTTAAAGCCATAGTTGATGAAATAGTAGAAAGATATAA
AAAAGGTCAACCAATGCTAGTAGGTACAGTAAGCATAGAAAAATCAGAAATGTTATCCTCTATGTTAAAGAAAAAAGGAG
TACCTCATCAAGTATTAAATGCTAAATATCATGAAAAAGAAGCGGAAATAATATCTCATGCAGGGGAATATGGGATGGTT
ACAATAGCCACCAATATGGCAGGTCGTGGTACAGATATAAAACTTACTAAAGAAGCTGAAGAAGCAGGCGGACTTATGAT
TATAGGTACAGAAAGACATGAGTCTAGAAGAATAGATAACCAATTAAGAGGACGTTCTGGTCGTCAAGGAGATCCTGGTG
AATCAAGATTTTTTGTATCTTTAGAAGATGATTTAATGAGAATATTTGGTTCAGAAAGAATACAAGGAATAGTTGATAAA
TTAGGACTCGCTGAAGATGAAGCCATAGAAAGTAAAATGGTAAGTTCAGCTATAGAAAGTGCTCAAAAGAAGGTAGAAGG
AAATAACTTTGATATAAGAAAAACTTTATTACAATATGATGATGTAATAAATAAACAAAGAGAAATAATCTATAAACAAA
GAAGTGAGGTTTTAGAGGGAGAAGACTTAAAGGATCAAATAAGAGATATGATAAGGGATGTGGTTTATACTGCAGTAAAT
TCTCATATTTCAGGAGTAGAAGAAGAGTTTGAAACAGAACTTCAAAATCTTGTTAATTATTTAGAAGATATATGCTTACC
AAAGGCCTTAGTAAAGGTAAAAGATATAAGTAATTTATCAGATGAAGAAATAAAAGAAAAATTATTAGAAGCAGTAGAAA
ATATATATAGCAACAAAGAAAAAGAAATTGGGGAAGAACAAATAAGAGAAATAGAAAGAGTAATATTACTTAGGGTTGTA
GATACTAAATGGATGGATCATATAGATGATATGGATCACTTAAAACAAGGTATAGGACTAAGAGCATATAGACAGCAAGA
TCCAGTTCAAGCATATCAATTTGAAGGTAGTGAAATGTTTGAGGAAATGATCTATAACATTAAAGTAGATACAGTAAGAT
ATTTATTCCATGTGGAAGTAGAAAAAGCACCTGAAAGAGAGAAAGTAGCAAAAGAAACATCAACTAATTATGATGAGGAT
TCAGTAAAAAAACAACCTATAAAAAAGGAAAATAGAATAGGTAGAAATGATCTATGTCCTTGTGGAAGTGGGAAAAAATA
TAAAAATTGTTGTGGTAGAATGGCATAA

Protein sequence :
MGILNKIFGTYSERELRRVNPIVNKIEALDEKMQSLKDEDFKLKTEEFKSRLEKGEKLDDILPEAFALVREAAHRTIGLK
HYREQLIGGVVLHQGRIGEMKTGEGKTLVATLPAYVNALTGKGVHIVTVNDYLAKRDRDLMAPVYEFLGLKVGVILHNLN
NEERQEAYGSDITYGTNSEFGFDYLRDNMVVYKEERVQRKLNFSIVDEVDSILIDEARTPLIISGQGEKSTEFYKVADYF
TKSLIAEKDFTIDEKANSAMLTDEGVNKAENFFKVDNYADAENMEIQHHVVQALKANYVMKKDKDYMIKDGEILIVDEFT
GRAMEGRRYSDGLHQAIEAKEGVRVERESKTLATITYQNYFRMYNKLSGMTGTAQTEENEFREIYGLDVIVIPTHEPIAR
IDNADVVYKSEKGKFKAIVDEIVERYKKGQPMLVGTVSIEKSEMLSSMLKKKGVPHQVLNAKYHEKEAEIISHAGEYGMV
TIATNMAGRGTDIKLTKEAEEAGGLMIIGTERHESRRIDNQLRGRSGRQGDPGESRFFVSLEDDLMRIFGSERIQGIVDK
LGLAEDEAIESKMVSSAIESAQKKVEGNNFDIRKTLLQYDDVINKQREIIYKQRSEVLEGEDLKDQIRDMIRDVVYTAVN
SHISGVEEEFETELQNLVNYLEDICLPKALVKVKDISNLSDEEIKEKLLEAVENIYSNKEKEIGEEQIREIERVILLRVV
DTKWMDHIDDMDHLKQGIGLRAYRQQDPVQAYQFEGSEMFEEMIYNIKVDTVRYLFHVEVEKAPEREKVAKETSTNYDED
SVKKQPIKKENRIGRNDLCPCGSGKKYKNCCGRMA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
secA2 YP_006310687.1 preprotein translocase subunit SecA2 Not tested FWisland_3 Protein 1e-120 41