Gene Information

Name : serS_1 (CLJ_B0021)
Accession : YP_002860887.1
Strain : Clostridium botulinum 657
Genome accession: NC_012658
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 22477 - 23757 bp
Length : 1281 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAGATTTAAAAAGAATAAGAAATAATTCAAATGAAATAAAAGAAGCATTAAACAATAGAGGAGAAAAGTTTGATGT
AACTGTAATTGATGAAGTCTTAAAATTAGATGAGGAAAGAAGAAACATTTTAGTTAAAGTTGAGGTTTTAAAAAGTAAGA
GAAATCAAGTTTCTTCTGAAGTTCCTAAACTAAAAAAAGAAGGAAAAGATGTATCTAATATAGTAGCTGAAATGAAGAAT
TTATCAGAAGAAATAAAAGGGTTTGATGCTACTTTAGCTAAAATAGATGAAAAAATACAATATATAATGCTTAGAATACC
TAATATACCAAACCCACAAGTTCCAGATGGAGAAACAGATGAGGATAATATAGAAATAAGAAATTGGTTAGAACCAACAA
AATTTGATTTTGAACCTAAAGCACATTGGGATATAGGAACAAATTTAAATATTCTTGATTTTCAAAGAGCTGGAAAAGTA
ACAGGATCAAGATTTACTTTTTATAAAGGATTAGGGGCTAGATTAGAAAGAGCAGTAATATCTTATTTTTTAGATACTCA
TACAGAAAAACATGGTTATATTGAAATATTACCACCTTATATGGTAAATAGAACAAGTATGATAGGAACAGGACAATTAC
CTAAATTTGAAGAAGACGCTTTTAAAATTTCAGAGGATGATTACTTTTTAATACCAACTGCAGAGGTTCCTGTAACTAAT
TTATATAGAGATGAAGTCTTAAAAGGTGATGAATTACCATTAAAACATGTAGCTTATAGTGCTTGTTTTAGATCAGAAGC
AGGTTCAGCAGGTAGAGATACAAGAGGTCTTGTTAGACAACATCAATTTAATAAAGTAGAGCTTGTTAAATTTACAAAAC
CAGAACAGTCTTATGACGAATTGGAAAAATTAACTAATGATGCTGAAACAGTATTAAAAGAGTTAGGTATTCCATATAGA
GTTGTAAGAATATGCAAAGGTGATTTAGGATTTACAGCTGCATTAAAATATGATTTAGAAGTTTGGATGCCAAGTTACAA
TAGATATGTTGAAATATCAAGCTGTAGTAACTTTGAAGACTTCCAAGCAAGACGTGCTAATATAAGATATAAAGAAGATT
CAAAAGCAAAACCACAATATGTTCATACATTAAATGGATCAGGAGTTGCTATTGGAAGAACTGTTGCAGCTATACTTGAA
AACTATCAAAATGAAGATGGATCAGTTACAATACCAGAAGTGTTAAGACCTTATATGGGAGGAAAAGAAGCAATAAAATA
G

Protein sequence :
MLDLKRIRNNSNEIKEALNNRGEKFDVTVIDEVLKLDEERRNILVKVEVLKSKRNQVSSEVPKLKKEGKDVSNIVAEMKN
LSEEIKGFDATLAKIDEKIQYIMLRIPNIPNPQVPDGETDEDNIEIRNWLEPTKFDFEPKAHWDIGTNLNILDFQRAGKV
TGSRFTFYKGLGARLERAVISYFLDTHTEKHGYIEILPPYMVNRTSMIGTGQLPKFEEDAFKISEDDYFLIPTAEVPVTN
LYRDEVLKGDELPLKHVAYSACFRSEAGSAGRDTRGLVRQHQFNKVELVKFTKPEQSYDELEKLTNDAETVLKELGIPYR
VVRICKGDLGFTAALKYDLEVWMPSYNRYVEISSCSNFEDFQARRANIRYKEDSKAKPQYVHTLNGSGVAIGRTVAAILE
NYQNEDGSVTIPEVLRPYMGGKEAIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 8e-128 60