Gene Information

Name : CLJ_B0109 (CLJ_B0109)
Accession : YP_002860941.1
Strain : Clostridium botulinum 657
Genome accession: NC_012658
Putative virulence/resistance : Virulence
Product : macrolide export ATP-binding/permease MacB
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1136
EC number : 3.6.3.-
Position : 99126 - 99821 bp
Length : 696 bp
Strand : +
Note : identified by match to protein family HMM PF00005

DNA sequence : 
ATGAAGATAATAAAGCTTAATAATGTAAATAAAGTATACAATTCTAAAAATAATAATGTAAATGCATTGAACAATATAGA
TTTGACAATTAATGAAGGAGAGCTGGTTGCAATAACTGGACCATCTGGATCAGGTAAATCTACTTTACTTAACATAATAG
GAACAATAGATAAAATTACAAGTGGCGAATATATATTAGAAAATAAAAGGATAGATAAACTGAAAAGTAATGAAGTAGCT
CAAATAAGAAATAAAATATTTGGTTTTGTAGTACAACATTTTGCATTAATTAGTGATTATACAGTATATGAAAACATAGA
AATACCATTGGAATATGCAAAAATTAAACATAATGATAGAAAAGTTATGATAGAAGATATAGTTTCTAAATTAGGATTAA
AAGAGAAAATAAATAAAAATGTTAAAGAACTTTCTGGAGGGCAATGTCAGAGAGTGGCTATATCAAGAGCTATAGTTAAT
AATCCAGAAATAATACTTGCAGATGAACCTACAGGAGCATTAGATCAAAAAACAGGACAAAAAGTATTAGATATTTTTAA
AGACTTAAATAAACAAGGTAAAACTGTTATTATAGTAACACATGATTTCAATATAGCTAATCAATGTGATAGAATCATAA
GATTAGAGGACGGATGTTTAAAAGAAGATAGTATAAAAGAGAAAACATGTATATAA

Protein sequence : 
MKIIKLNNVNKVYNSKNNNVNALNNIDLTINEGELVAITGPSGSGKSTLLNIIGTIDKITSGEYILENKRIDKLKSNEVA
QIRNKIFGFVVQHFALISDYTVYENIEIPLEYAKIKHNDRKVMIEDIVSKLGLKEKINKNVKELSGGQCQRVAISRAIVN
NPEIILADEPTGALDQKTGQKVLDIFKDLNKQGKTVIIVTHDFNIANQCDRIIRLEDGCLKEDSIKEKTCI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
Spaf_1862 YP_006310627.1 amino acid ABC transporter ATP-binding protein Not tested FWisland_2 Protein 2e-35 46
Cp1002_1464 YP_005681730.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 5e-24 43
CpC231_1466 YP_005683828.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 2e-25 43
cpfrc_01473 YP_003783873.1 hypothetical protein Not tested PiCp 5 Protein 2e-25 43
CpI19_1473 YP_005685914.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 2e-25 43
unnamed AAP55232.1 unknown Not tested SaPIbov2 Protein 7e-29 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CLJ_B0109 YP_002860941.1 macrolide export ATP-binding/permease MacB NC_012469.1.7686878. Protein 9e-43 52
CLJ_B0109 YP_002860941.1 macrolide export ATP-binding/permease MacB NC_012469.1.7686946. Protein 1e-32 45
CLJ_B0109 YP_002860941.1 macrolide export ATP-binding/permease MacB NC_008702.1.4606598. Protein 4e-36 45
CLJ_B0109 YP_002860941.1 macrolide export ATP-binding/permease MacB CP001581.1.gene598.p Protein 3e-35 44
CLJ_B0109 YP_002860941.1 macrolide export ATP-binding/permease MacB CP001581.1.gene798.p Protein 5e-31 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CLJ_B0109 YP_002860941.1 macrolide export ATP-binding/permease MacB VFG0869 Protein 3e-23 41