Gene Information

Name : thyA (cauri_0792)
Accession : YP_002834327.1
Strain : Corynebacterium aurimucosum ATCC 700975
Genome accession: NC_012590
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 865891 - 866697 bp
Length : 807 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGGCGACCATGATTGAGACTCCGTACGAGGACCTCCTGCGCCGCGTCCTGGAAGAAGGCGCTCCCAAAGGCGACCGCAC
TGGCACCGGCACCCTCTCCCTGTTCGGTGCCCAGCTTCGCTATAACCTGGCGGAGTCTTTTCCCCTGCTGACCACCAAGA
AGGTCTACTTCCACGGCGTGATTGGTGAGCTGCTGTGGTTCCTGCGCGGTGACTCCAACGTGAAGTGGCTGCAGGAGAAC
AAGGTTCGCATCTGGAACGAGTGGGCCGATGAGGACGGTGAGCTAGGCCCCGTCTACGGCGTGCAATGGCGCTCGTGGCC
CACACCGGATGGCCAGCACATCGACCAGATTCAGGTCGCGCTGGACACGCTCAAGAACAACCCGGATTCCCGCCGCAACT
TGGTCTCCGCGTGGAACGTCTCTGAGTTGGACAAGATGGCGCTCATGCCCTGCCACTTGCTTTTCCAGCTTTATGTCGCC
GACGGCAAGTTGTCCATGCAGGTTTACCAGCGCTCGGCGGACATGTTCCTCGGCGTTCCCTTCAACTTAGCCTCCTACGC
GGCGCTGACTCACATGTTTGCGCAGCAAGCAGGTTTAGAGGTAGGCGAGCTCATCTGGACCGGCGGAGATTGCCACATCT
ACAACGACCACATCGAGCAGGTTAAGGAACAGCTCTCCCGTCAGCCCCGCGAGTACCCACAGCTCAAACTCCACAAGGCT
GAGAGCCTCTTTGACTATGACTTCGATGATTTTGAGGTCATCGGCTACGACCCCCACCCCACCATCAAGGCGCAGGTGTC
CGTTTAA

Protein sequence :
MATMIETPYEDLLRRVLEEGAPKGDRTGTGTLSLFGAQLRYNLAESFPLLTTKKVYFHGVIGELLWFLRGDSNVKWLQEN
KVRIWNEWADEDGELGPVYGVQWRSWPTPDGQHIDQIQVALDTLKNNPDSRRNLVSAWNVSELDKMALMPCHLLFQLYVA
DGKLSMQVYQRSADMFLGVPFNLASYAALTHMFAQQAGLEVGELIWTGGDCHIYNDHIEQVKEQLSRQPREYPQLKLHKA
ESLFDYDFDDFEVIGYDPHPTIKAQVSV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 8e-100 76