Gene Information

Name : guaA (cauri_0485)
Accession : YP_002834020.1
Strain : Corynebacterium aurimucosum ATCC 700975
Genome accession: NC_012590
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 518240 - 519808 bp
Length : 1569 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACCGTGACTAACCCAAATACAACCCCGCGTCCTGTCCTCGTGGTGGACTTTGGCGCCCAGTACGCGCAGCTCATCGC
CCGGCGCGTGCGTGAGGCCAACATCTACTCCGAGGTTGTCCCCAATTCCGCCTCCGTGGAGGACATCAAGGCCAAGAACC
CGGCCGCGCTGATCCTCTCCGGTGGCCCGTCCTCCGTATACGCGGACGGCGCCCCTGCACTGAAGCCGGAGCTGCTCGAA
CTCGGCATCCCGGTCTTTGGTATCTGCTACGGCTTCCAGTCCATGACCCAAGCCTTGGGCGGTACCGTGGCCTCCACTGG
TGCCCGCGAGTACGGTCGCACGGACATGACCGTGTCCGGCGGCGTGCTCCACAAGGGTCTGGAGGACACCCACAAGGTGT
GGATGTCGCACGGCGATTCGGTCTCTGAAGCCCCGGAGGGCTTTGAGGTCACCGCCTCTTCCGAGGGCGCTCCCGTGGCC
GCCTTCGAGTGCCTGTCCAAGAAGATGGCCGGCGTGCAGTACCACCCGGAAGTTCTCCACTCGCCGCACGGCCAAGAGGT
GCTCACGCGCTTCCTGACTGAGGTCGCAGGTTTGGAGCAGAACTGGACCGCAGAGAACATTGCGGAGCAGCTCATTAACG
ATGTGCGTGAGCAGATCGGCGAGGAAGGCCGCGCGATCTGCGGCCTGTCCGGCGGCGTGGATTCCGCCGTGGCAGCAGCG
CTGGTGCAGCGTGCAATCGGTGACCGTTTGACCTGTGTCTTCGTCGATCACGGCCTGCTGCGCGCGGGTGAGCGTGAGCA
GGTGGAGAAGGACTTCGTGGCGTCGACTGGCGCCAAGCTCATCACCGCTGATGAGCGCGAGGCCTTCCTCAACAAGCTGG
CCGGTGTGACCGAACCGGAGGCCAAGCGCAAGGCCATCGGCGCGGAGTTCATCCGCTCCTTCGAGCGCGCCGTCGACCAG
GCTCTGGACGGCCAGGACGCCGCGTTCTTGGTGCAGGGCACGCTGTACCCGGACGTGGTGGAGTCCGGTGGCGGTGACGG
CACCGCGAACATTAAGTCTCACCACAACGTGGGCGGCCTGCCAGACGACGTCGAGTTCGAGCTCGTCGAGCCGCTGCGCC
TGCTCTTCAAGGATGAGGTGCGCGCCGTCGGCCGTGAGCTGGGCCTGCCGGAGGAAATCGTGGCGCGCCAGCCATTCCCG
GGCCCGGGCCTGGGTATCCGCATCATCGGTGAGGTCACCGAGGAGCGCCTCGAGACGCTGCGCCAGGCGGACCTCATCGC
GCGTACCGAGCTGACCAACGCTGGCCTGGACGGCGAGATTTGGCAGTGCCCGGTGGTGCTGCTTGCCGACGTCCGCTCCG
TCGGCGTCCAGGGCGACGGCCGCACCTATGGCCACCCGATCGTCCTGCGCCCGGTGTCCTCCGAGGACGCCATGACCGCG
GACTGGACCCGCCTGCCGTACGACGTGCTGGAGAAGATCTCCACCCGCATCACCAACGAGGTCAAGGAAGTCAACCGCGT
GGTGCTCGACGTAACCTCGAAGCCGCCCGGAACCATCGAGTGGGAGTAA

Protein sequence :
MTVTNPNTTPRPVLVVDFGAQYAQLIARRVREANIYSEVVPNSASVEDIKAKNPAALILSGGPSSVYADGAPALKPELLE
LGIPVFGICYGFQSMTQALGGTVASTGAREYGRTDMTVSGGVLHKGLEDTHKVWMSHGDSVSEAPEGFEVTASSEGAPVA
AFECLSKKMAGVQYHPEVLHSPHGQEVLTRFLTEVAGLEQNWTAENIAEQLINDVREQIGEEGRAICGLSGGVDSAVAAA
LVQRAIGDRLTCVFVDHGLLRAGEREQVEKDFVASTGAKLITADEREAFLNKLAGVTEPEAKRKAIGAEFIRSFERAVDQ
ALDGQDAAFLVQGTLYPDVVESGGGDGTANIKSHHNVGGLPDDVEFELVEPLRLLFKDEVRAVGRELGLPEEIVARQPFP
GPGLGIRIIGEVTEERLETLRQADLIARTELTNAGLDGEIWQCPVVLLADVRSVGVQGDGRTYGHPIVLRPVSSEDAMTA
DWTRLPYDVLEKISTRITNEVKEVNRVVLDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 0.0 89
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 9e-131 52
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 8e-131 52
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-130 52