Gene Information

Name : leuS (cauri_2469)
Accession : YP_002835998.1
Strain : Corynebacterium aurimucosum ATCC 700975
Genome accession: NC_012590
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 2706305 - 2709154 bp
Length : 2850 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGACTAACCCGAGCGATAACACCACCCACCGCTACACGCCGGAGCTCGCCGCGCAGATTGAAAGTGCCTGGCAGCAGTA
CTGGAAGGACAACGGTACGTTCAACGCGCCGAACCCAGTTGGGCCGCTCGCGGAGGAGGGTAAGGAACTTCCCGCGGAGA
AGATGAACATTCAGGACATGTTCCCCTACCCGTCTGGCGCGGGTCTGCACGTGGGCCACCCGCTGGGTTATATCGCCACG
GATACTTATGCCCGCTTTAACCGCATGCTGGGCAAGAACGTCCTGCACACGCTGGGTTATGACGCCTTTGGCCTGCCAGC
GGAGCAGTACGCCATCCAGACTGGTACGCACCCGCGCACCACCACGGAGGCGAATATCAACAATATGCGCCGCCAGCTGG
GCATGCTGGGTCTGGGCCACGATCCGCGCCGCTCGGTGGCTTCGACTGACCCGGAGTTTTATAAGTGGACGCAGTGGATC
TTCCTGCAGATTTATAACTCCTGGTTTGATGAGGAGCAGCAGAAGGCACGCCCGATTTCTGAGCTCATCAAGGAACTTGA
GGTGGGCAAGCGCACCACCAAGGATGGTCGCTACTACGCGGATCTGACCAAGGAAGAGCAGCGCCAAGCACTCGATGAAT
TCCGTCTGGTCTATCTGTCTAACTCCACCGTGAACTGGTGCCCGGGCCTGGGCACGGTGCTGGCCAACGAGGAGGTCACC
GCGGAGGGCAAGTCCGAGCGCGGTAACTTCCCGGTCTTCCGCAAGAACCTGCGCCAGTGGATGATGCGCATTACCGCTTA
CTCGGACCGCCTGCTCGATGACCTGGAGCTTCTGGATTGGCCGGAGAAGGTCAAGTCCATGCAGCGTAACTGGATTGGCC
GCTCCCGTGGTGCAGAGGTCAGCTTCCACGCCGAGGGTTACAACATCGACGTCTTCACCACCCGCCCGGATACCCTCTTC
GGCGCCGAGTACGTGGTGCTGGCCCCGGAACACGAGCTTGTCGACGCCCTCCTCTCCCCCATCCCCTACGAGGATGATGT
GGATAAGCGCTGGACCTTCGGCCACGATGATCCGAAGGAGGCCGTAGAGGCCTACCGCGCCTCCATTGCCGCGAAGTCCG
ACCTCGAGCGCCAGGAGAACAAGGAAAAGACCGGTGTCTTCCTGGGCACCTACGCCACCAACCCGGTCAACGGCAAGCAG
ATCCCGATCTTCATCGCGGACTACGTTCTGACCGGCTACGGTACCGGCGCCATCATGGCGGTCCCGGCGCACGATACCCG
TGACTACGAGTTTGCTACCGTCTTTGGCCTGCCGATTACTGAGGTGGTTGCTGGCGGCGACATCACCAAGGAGGCGTACA
CGGAGTCCGGCCAGGCTGTGAACTCCGCCAACGATTCTTTGGACATCAACGGCATGTCCAAGGATGAGGCAATCGCCACC
ATCATTCCATGGCTGGAGGAGCAGGGAGTAGGCCGCGAGAAGATCCAGTACAAGCTGCGTGACTGGCTGTTTGCCCGTCA
GCGCTACTGGGGCGAGCCCTTCCCCATCGTTTACGACGAGGCCGGCCAGGCCTACCCGCTGCCGGAGTCGATGCTGCCCA
TCGAACTGCCGGAGGTAGAAGACTACAAGCCGGTCTCCTTTGACCCGGACGATGCCGATTCCTCCCCGCAGCCGCCGCTG
GCCAAGGCCCGCGAGTGGGTCGAGGTGGAGCTGGACCTGGGTCTTGGGGATGGCCCCAAGACTTACTACCGCGATACCAA
CGTCATGCCGCAGTGGGCAGGTTCTTCCTGGTACCAGCTGCGCTACATCGATCCGACGAATGACGAGATCTTCTGCGACT
TGGAGAACGAGCGCTACTGGACTGGCCCGCGCACAGAAGAGCACGGCGCCAACGACCCGGGTGGCGTTGACCTCTACGTC
GGTGGCGTTGAGCACGCCGTGCTGCACCTGCTCTACGCTCGTTTCTGGCACAAGGTGCTCTTCGACCTGGGCTACGTGAG
CTCCAAGGAGCCCTACCGCCGCCTCTACAACCAGGGCTATATCCAGGCCTATGCCTACACCGATTCCCGCGGCGTCTACG
TCCCGGCCGCCGAGGTTGAGGAGAAGGATGGCAAATTCTACTACAACGGTGAAGAGGTCAACCAGGAGTACGGAAAGATG
GGCAAGTCCCTGAAGAACTCCGTCGCCCCGGATGACATTTGCCGCGACTATGGTGCCGATACCCTGCGCGTGTACGAGAT
GTCCATGGGCCCGCTGGATACTTCCCGCCCGTGGGCAACCAAGGACGTCGTCGGTGCGCAGCGCTTCTTGCAGCGCCTGT
GGCGCTTGGCTATCGACGAGAACTCTGGCGAGCTGTCGACGACGGACGCAGAGCTTTCCGAGGATGACCTGAAGCACCTC
AACCGCACCATCGCCGGCGTGCGCGATGATTACGAGAACCTGCGCCTGAACACCGTGGTGGCCAAGCTCATCGAGTACGT
GAATTACCTGACCAAGGCCTACCCGAAGGGCGCGCCGCGTGCCGCCGTGGAGCCCTTGGCCCAGCTGGTCTCCCCCGTTG
CCCCGCACATCGCGGAGGAGCTGTGGAAGCGCTTCGGTCATGAGGGGACCATCACCTACGAGGCTTTCCCGGAGTTCGAC
GAGAAGTACCTGGTCGATGACGAGATCGAGGTTCCGGTGCAGATCAACGGCAAGGTCAAGGCACGCGTGATGGTGCCTGC
TGACGCCGACCAAGCCACCGTCGTGGGCATCGCCAAGGACGATGAGCGCATCGCTGAGCTGACCGCTGGAAAGAACGTGG
TCAAGGAGATCTACGTCCCGGGCCGCATGGTCAACCTGGTGGTGAAGTAA

Protein sequence :
MTNPSDNTTHRYTPELAAQIESAWQQYWKDNGTFNAPNPVGPLAEEGKELPAEKMNIQDMFPYPSGAGLHVGHPLGYIAT
DTYARFNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRTTTEANINNMRRQLGMLGLGHDPRRSVASTDPEFYKWTQWI
FLQIYNSWFDEEQQKARPISELIKELEVGKRTTKDGRYYADLTKEEQRQALDEFRLVYLSNSTVNWCPGLGTVLANEEVT
AEGKSERGNFPVFRKNLRQWMMRITAYSDRLLDDLELLDWPEKVKSMQRNWIGRSRGAEVSFHAEGYNIDVFTTRPDTLF
GAEYVVLAPEHELVDALLSPIPYEDDVDKRWTFGHDDPKEAVEAYRASIAAKSDLERQENKEKTGVFLGTYATNPVNGKQ
IPIFIADYVLTGYGTGAIMAVPAHDTRDYEFATVFGLPITEVVAGGDITKEAYTESGQAVNSANDSLDINGMSKDEAIAT
IIPWLEEQGVGREKIQYKLRDWLFARQRYWGEPFPIVYDEAGQAYPLPESMLPIELPEVEDYKPVSFDPDDADSSPQPPL
AKAREWVEVELDLGLGDGPKTYYRDTNVMPQWAGSSWYQLRYIDPTNDEIFCDLENERYWTGPRTEEHGANDPGGVDLYV
GGVEHAVLHLLYARFWHKVLFDLGYVSSKEPYRRLYNQGYIQAYAYTDSRGVYVPAAEVEEKDGKFYYNGEEVNQEYGKM
GKSLKNSVAPDDICRDYGADTLRVYEMSMGPLDTSRPWATKDVVGAQRFLQRLWRLAIDENSGELSTTDAELSEDDLKHL
NRTIAGVRDDYENLRLNTVVAKLIEYVNYLTKAYPKGAPRAAVEPLAQLVSPVAPHIAEELWKRFGHEGTITYEAFPEFD
EKYLVDDEIEVPVQINGKVKARVMVPADADQATVVGIAKDDERIAELTAGKNVVKEIYVPGRMVNLVVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 1e-149 48