Gene Information

Name : guaA (NGR_c36520)
Accession : YP_002828126.1
Strain : Sinorhizobium fredii NGR234
Genome accession: NC_012587
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 3861151 - 3862713 bp
Length : 1563 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACCCAGACAGCCCATCCCGACACCGTGCTCATCGTCGATTTCGGCAGCCAGGTGACGCAACTCATCGCCCGGCGCGT
GCGCGAAGCCGGTGTCTATTGCGAGATCGTACCATTCCAGTCGGCCGAAGAGGGCTTCAAGCGCCTGAAACCGAAGGCGG
TGATCCTGTCCGGAAGCCCGGCCTCGACGCTCGACATCGGGTCGCCTCGCGCGCCATCGGTGATCTTCGAAAGCGGCCTG
CCGGTCTTCGGCATCTGCTACGGCCAGCAGACCATGTGCGCCCAGCTCGGCGGCAAGGTCGAGAGCGGCCATCACCGCGA
ATTCGGCCGCGCCTTCCTGGAGGTCGAGAAGGACTGTGCCCTCTTCGACGGGCTCTGGTCGCTCGGCTCCCGCCATCAGG
TCTGGATGTCGCACGGCGACCGGGTGACAGCGCTGCCGGAAGGCTTCGAGGTGGTGGCGACCTCTTCGAATGCGCCCTTT
GCTTTCATCGCCGACGAGACGCGCAAATATTACGCCGTGCAGTTCCATCCGGAAGTGGTGCATACGCCGGACGGCGCCAA
GCTGATCTCCAACTTCGTCCACAAGATCGCCGGCATCAAGGGCGACTGGACGATGTCGGCCTACCGCGCCAAGGCGGTCG
AGGCGATCCGCAAACAAGTCGGCGGCAAGAAGGTGATCTGCGCGCTTTCGGGCGGCGTCGATTCTTCCGTGGCGGCGCTG
CTCATCCATGAGGCCGTCGGCGACCAGCTCACCTGCATCCTCGTCGACCACGGCCTGATGCGCAAGGACGAGGCGGCGAA
TGTCGTCGCCATGTTCCAGGAGCACTACAACCTCCACCTCCTCCACATCGACGCGTCCGACCGCTTCATCGGCGAGCTCG
AGGGCGTCAGCGATCCGGAGACCAAGCGCAAGATCATCGGCCGTCTCTTCATCGAGGTCTTCGAGGAAGAGGCGAAGAAG
CTCGGTGGCGCCGATTTCCTCGCCCAGGGGACGCTCTATCCGGACGTGATCGAAAGCGTTTCCTTCACCGGCGGCCCGTC
GGTGACGATCAAGTCGCACCACAATGTCGGCGGCCTGCCGGAGCGGATGAACATGCAGCTCGTCGAGCCGCTGCGCGAAC
TCTTCAAGGACGAGGTGCGCGTGCTCGGCCGCGAGCTCGGCCTGCCCGAGAGCTTCATCGGCCGCCATCCCTTCCCCGGC
CCGGGCCTTGCCATCCGCTGCCCCGGCGGCATCAGCCGCGAGAAGCTCGAAATACTGCGCGAGGCCGATGCGATCTATCT
CGACGAGATCCGCAAGGCGGGCCTCTACGACGCCATCTGGCAGGCCTTCGCCGTGCTGCTGCCGGTGCAGACGGTGGGCG
TCATGGGCGACGGGCGCACCTACGAGTTCGTCTGTGCGTTGCGCGCCGTCACCTCGGTCGACGGCATGACCGCCGACTTC
TACCACTACGACATGGAATTCCTCGGTCGCGCCGCAACCCGCATCATCAACGAGGTGCGCGGCATCAACCGCGTCGTCTA
CGACGTCACTTCGAAGCCGCCCGGCACGATCGAGTGGGAGTGA

Protein sequence :
MTQTAHPDTVLIVDFGSQVTQLIARRVREAGVYCEIVPFQSAEEGFKRLKPKAVILSGSPASTLDIGSPRAPSVIFESGL
PVFGICYGQQTMCAQLGGKVESGHHREFGRAFLEVEKDCALFDGLWSLGSRHQVWMSHGDRVTALPEGFEVVATSSNAPF
AFIADETRKYYAVQFHPEVVHTPDGAKLISNFVHKIAGIKGDWTMSAYRAKAVEAIRKQVGGKKVICALSGGVDSSVAAL
LIHEAVGDQLTCILVDHGLMRKDEAANVVAMFQEHYNLHLLHIDASDRFIGELEGVSDPETKRKIIGRLFIEVFEEEAKK
LGGADFLAQGTLYPDVIESVSFTGGPSVTIKSHHNVGGLPERMNMQLVEPLRELFKDEVRVLGRELGLPESFIGRHPFPG
PGLAIRCPGGISREKLEILREADAIYLDEIRKAGLYDAIWQAFAVLLPVQTVGVMGDGRTYEFVCALRAVTSVDGMTADF
YHYDMEFLGRAATRIINEVRGINRVVYDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-136 54
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-136 54
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-136 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-115 49