Gene Information

Name : serS (NGR_c13740)
Accession : YP_002825907.1
Strain : Sinorhizobium fredii NGR234
Genome accession: NC_012587
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1417877 - 1419160 bp
Length : 1284 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTCGATATCAAATGGATTCGTGAGAATGCTGGCGTGCTCGACAATGCCCTGGCGAAGCGGGGCGCGGAGCCGCTATC
CGCATCGCTGATCGCCCTTGACGAGCGCCGCCGCACGGTCTTGCAGTCGCTCCAGGAGATGCAGTCGCGCCGCAACGCCG
CCTCGAAGGAAATCGGCGCGGCCATGGCGCAGAAGAACAGCGAACTGGCCGAAAAACTCAAGGCCGAGGTTGCCGAGCTG
AAGGACGCTCTGCCGGCCGCCGAGGAGGAAAGCCGGCGGATGGAAGCCGAACTCACCGATATCCTGTCGCGCATTCCGAA
CGTTCCACTCGAGGACGTGCCCGTCGGTCCGGACGAGAGCGGCAATGTCGTCAAGCGGCTCGTCGGCAGCAAGCCCACCT
GGAACCACAAGCCCCTTGAGCATTTCGAGATCGGCGAGGGCCTGGGGTTCATGGATTTCGAGGGGGCGGCGCGCATTGCC
GGCTCGCGTTTCACCATTCTGAAAGGGCAGCTTGCCCGCCTGGAGCGCGCGCTTGGCCAGTTCATGCTGGACCTGCACAC
GCAGGAGCACGGCTATATCGAGGTGCAGCCGCCGCTGCTTGTTCGTGACGATGCGATGTACGGGACCGGTCAGCTGCCGA
AATTCGCGGAAGATCTCTTCCGCACGACGGACGGTCGCTGGTTGATTCCGACCGCGGAGGTTCCGCTGACGAACATGGTG
CGCGAGCAGATCCTCGAGGGCGAGAAGCTGCCGCTGCGTTTCACGGCCCTGACGCCGTGTTTCCGCTCGGAAGCAGGTTC
GGCCGGGCGCGACACGCGCGGCATGCTGCGCCAGCACCAGTTCAACAAGGTCGAACTGGTGTCGCTCACCGACGCCGAGA
CTTCGGTCGATGAGCACGAGCGGATGACCGCCTGCGCCGAAGAGGTTCTGAAGCGGCTCGGCCTGCATTACCGCGTCATG
ACGCTCTGCACCGGCGACATGGGCTTTGGCGCCCGCAAGACCTACGACCTCGAAGTCTGGCTGCCGGGGCAGGATGCCTA
CCGCGAAATCTCTTCCTGCTCGGTCTGCGGCGACTTCCAGGCACGGCGCATGAACGCGCGCTATCGCAGCAAGGAAGAGA
AGGGCACGAAGTTCGTCCACACGCTGAACGGTTCCGGCGTCGCCGTCGGCCGCGCGCTGATCGCCGTCATCGAGAACTAT
CTGAACGAGGATGGCTCCGTCTCCGTGCCGGAAGTTCTGGTTCCCTACATGGGGGGCCTGCGACGCGTCGAGAAAGCGGC
CTGA

Protein sequence :
MLDIKWIRENAGVLDNALAKRGAEPLSASLIALDERRRTVLQSLQEMQSRRNAASKEIGAAMAQKNSELAEKLKAEVAEL
KDALPAAEEESRRMEAELTDILSRIPNVPLEDVPVGPDESGNVVKRLVGSKPTWNHKPLEHFEIGEGLGFMDFEGAARIA
GSRFTILKGQLARLERALGQFMLDLHTQEHGYIEVQPPLLVRDDAMYGTGQLPKFAEDLFRTTDGRWLIPTAEVPLTNMV
REQILEGEKLPLRFTALTPCFRSEAGSAGRDTRGMLRQHQFNKVELVSLTDAETSVDEHERMTACAEEVLKRLGLHYRVM
TLCTGDMGFGARKTYDLEVWLPGQDAYREISSCSVCGDFQARRMNARYRSKEEKGTKFVHTLNGSGVAVGRALIAVIENY
LNEDGSVSVPEVLVPYMGGLRRVEKAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-91 49