Gene Information

Name : alo (BAMEG_1271)
Accession : YP_002813874.1
Strain : Bacillus anthracis CDC 684
Genome accession: NC_012581
Putative virulence/resistance : Virulence
Product : anthrolysin O
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1150793 - 1152331 bp
Length : 1539 bp
Strand : +
Note : identified by match to protein family HMM PF01289

DNA sequence :
GTGATTTTTCTGAATATTAAGAAAAACACTAAAAGAAGAAAGTTCCTTGCATGTTTATTAGTTAGTCTATGTACCATTCA
TTATTCGTCTATTTCTTTTGCAGAAACACAAGCCGGTAATGCAACTGGTGCAATAAAAAATGCTAGTGATATTAATACTG
GTATAGCAAATCTAAAGTATGATAGTAGAGATATTTTAGCAGTAAATGGTGATAAAGTAGAGAGTTTTATTCCGAAAGAG
AGTATCAATTCAAACGGTAAATTTGTAGTAGTGGAACGCGAGAAAAAATCACTTACAACGTCACCAGTCGATATTTTGAT
TATTGATTCTGTAGTGAATCGTACGTATCCAGGAGCTGTACAACTTGCCAATAAAGCATTTGCAGACAATCAACCGAGTT
TATTAGTAGCTAAGAGAAAGCCTTTGAATATTAGTATAGACTTACCTGGCATGAGAAAAGAAAATACAATCACTGTCCAA
AATCCGACATATGGTAATGTGGCTGGAGCAGTAGATGATTTAGTATCTACTTGGAATGAAAAGTATTCCACAACACATAC
GTTACCTGCAAGAATGCAGTATACAGAATCTATGGTTTATAGTAAATCACAAATCGCAAGTGCTCTTAATGTTAATGCTA
AATATCTTGATAACAGTCTAAATATTGACTTTAATGCAGTTGCAAATGGAGAAAAGAAAGTGATGGTGGCGGCATATAAA
CAAATATTTTATACTGTAAGTGCTGAACTACCTAATAATCCATCTGATCTCTTTGATAATAGTGTTACTTTTGATGAGTT
AACTCGTAAAGGAGTAAGTAATTCGGCTCCACCTGTTATGGTTTCAAATGTAGCTTATGGTAGAACGGTTTATGTAAAAT
TAGAAACAACATCTAAGAGTAAAGATGTACAAGCTGCATTTAAAGCTCTACTTAAGAATAACAGCGTCGAAACGAGTGGA
CAGTACAAAGATATTTTTGAAGAAAGTACCTTTACTGCTGTAGTATTAGGCGGAGATGCGAAAGAGCATAACAAGGTTGT
TACAAAAGATTTCAATGAAATCCGAAATATTATTAAAGATAATGCTGAATTAAGCTTTAAAAATCCAGCATACCCAATTT
CATATACAAGCACGTTCTTAAAAGATAATGCAACTGCTGCTGTTCATAACAATACAGATTATATCGAGACGACAACTACA
GAATATTCAAGTGCTAAAATGACACTCGATCATTACGGTGCTTACGTTGCTCAATTTGATGTATTTTGGGATGAATTTAC
ATTTGATCAAAATGGGAAAGAAGTACTAACACATAAAACATGGGAAGGTAGTGGCAAAGACAAAACAGCCCATTACTCTA
CAGTTATCCCTCTTCCACCAAATTCAAAAAATATAAAAATCGTTGCAAGAGAATGTACAGGTCTTGCATGGGAATGGTGG
AGAACTATCATTAATGAACAAAATGTTCCATTAACAAATGAAATAAAGGTTTCAATTGGAGGAACAACATTATATCCAAC
TGCTACTATTAGTCATTAG

Protein sequence :
MIFLNIKKNTKRRKFLACLLVSLCTIHYSSISFAETQAGNATGAIKNASDINTGIANLKYDSRDILAVNGDKVESFIPKE
SINSNGKFVVVEREKKSLTTSPVDILIIDSVVNRTYPGAVQLANKAFADNQPSLLVAKRKPLNISIDLPGMRKENTITVQ
NPTYGNVAGAVDDLVSTWNEKYSTTHTLPARMQYTESMVYSKSQIASALNVNAKYLDNSLNIDFNAVANGEKKVMVAAYK
QIFYTVSAELPNNPSDLFDNSVTFDELTRKGVSNSAPPVMVSNVAYGRTVYVKLETTSKSKDVQAAFKALLKNNSVETSG
QYKDIFEESTFTAVVLGGDAKEHNKVVTKDFNEIRNIIKDNAELSFKNPAYPISYTSTFLKDNATAAVHNNTDYIETTTT
EYSSAKMTLDHYGAYVAQFDVFWDEFTFDQNGKEVLTHKTWEGSGKDKTAHYSTVIPLPPNSKNIKIVARECTGLAWEWW
RTIINEQNVPLTNEIKVSIGGTTLYPTATISH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
slo YP_281505.1 streptolysin O Virulence Not named Protein 4e-150 62
hly AAA69525.1 listeriolysin O Virulence LIPI-1 Protein 8e-100 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
alo YP_002813874.1 anthrolysin O VFG2275 Protein 3e-171 69
alo YP_002813874.1 anthrolysin O VFG0976 Protein 9e-151 62
alo YP_002813874.1 anthrolysin O VFG1363 Protein 3e-101 43
alo YP_002813874.1 anthrolysin O VFG0074 Protein 7e-100 42