Gene Information

Name : pykA1 (BAMEG_1243)
Accession : YP_002813847.1
Strain : Bacillus anthracis CDC 684
Genome accession: NC_012581
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1125488 - 1126546 bp
Length : 1059 bp
Strand : +
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence : 
ATGACAATCGATCGAGTTTGTACAATTGGGCCAGCAAGTAATAATAAAGAAACGTTAGCGAAGTTAATAAACAATGGTAT
GAAAATTGTTCGTCTAAATTTATCACATGGTACGCATGAAAGTCATAAAGATATTATTCGTTTAGTGAAATCGTTAGATG
ATTCTATTAAAATTTTAGGCGATGTACAAGGTCCTAAAATAAGGTTAGGTGAAATAAAAGGAGAACAAATTACACTTCAG
GCGGGAGATTCTTTTATGTTACGTACGCAACCAGTTACAGGGAGTAGTACGGAAGCAAGTGTTGATTATGAAGGAATCGC
GAATGATGTGAAAGTTGGAAGTAGAATTTTAATGAATGATGGCGAAGTTGAGTTAATTGTTGAGAAGGTAAGTACGGATA
AAATAGAAACAAAGGTCAAAACAGGTGGTAATATCTCATCACATAAAGGAGTGAACTTACCAGGGGCAATCGTTAGTTTA
CCAGCTATTACAGAGAAAGATAAAAAAGATATTCAGTTTCTTTTAGAAGAGGATGTTGATTTTATTGCGTGTTCTTTCGT
AAGAAAACCTAGTCATATAAAAGAAATACGAGATTTTATACAACAGTATAAAGAAACGTCACCTAATTTAATTGCAAAAA
TAGAAACGATGGAAGCAATCGAGAATTTTCAAGATATATGTAAAGAAGCAGACGGAATTATGATTGCAAGGGGCGATTTA
GGAGTTGAGTTGCCGTATCAATTTATTCCGCTCTTGCAGAAAATGATGATTCAGGAATGTAATCGAACGAATACATATGT
TATTACAGCGACACAAATGCTTCAATCTATGGTAGATCATTCGATTCCAACAAGGGCTGAGGTAACTGATGTGTTTCAAG
CTGTACTGGATGGAACGAATGCTGTTATGCTTTCTGCTGAAAGTGCTTCAGGAGAGCATCCGGTTGAAAGTGTGAGTACA
CTACGTCTCGTTTCTGAATTTGCTGAGCATGTAAAAAAAGACGGTCCTTTTGTGATGAAAGATGTACTGGAATTGCTGCA
TAAATCTTTGGATGAGTGA

Protein sequence : 
MTIDRVCTIGPASNNKETLAKLINNGMKIVRLNLSHGTHESHKDIIRLVKSLDDSIKILGDVQGPKIRLGEIKGEQITLQ
AGDSFMLRTQPVTGSSTEASVDYEGIANDVKVGSRILMNDGEVELIVEKVSTDKIETKVKTGGNISSHKGVNLPGAIVSL
PAITEKDKKDIQFLLEEDVDFIACSFVRKPSHIKEIRDFIQQYKETSPNLIAKIETMEAIENFQDICKEADGIMIARGDL
GVELPYQFIPLLQKMMIQECNRTNTYVITATQMLQSMVDHSIPTRAEVTDVFQAVLDGTNAVMLSAESASGEHPVESVST
LRLVSEFAEHVKKDGPFVMKDVLELLHKSLDE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 4e-63 43
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-63 43
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-63 43
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-62 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pykA1 YP_002813847.1 pyruvate kinase VFG0479 Protein 1e-63 43