Gene Information

Name : tktA-1 (VCM66_0458)
Accession : YP_002809234.1
Strain :
Genome accession: NC_012578
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 486374 - 488458 bp
Length : 2085 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
TTGCAGCAGCAGGGGGGCTTTGCGACAATAGCCGCCACTGATTTTCCGCATCCATTCATTTCGCTTACTTCCCATTTAGG
AGTCGACATGTCTTCTCGCAAACAACTTGCCAATGCTATCCGCGCCCTGAGCATGGACGGCGTTCAAAAAGCTAACTCTG
GCCACCCGGGAGCCCCAATGGGCATGGCGGATATCGCCGAAGTGCTGTGGCGTTCACACTTAAACCACAACCCACAAAAC
CCAAACTGGGCTGACCGCGACCGTTTCGTACTGTCTAACGGCCACGGCTCTATGCTGATTTACTCGCTGCTACACCTGAG
CGGCTATGAGCTGTCGATTGACGATTTGAAAAACTTCCGTCAACTACACTCCAAAACACCGGGTCACCCAGAGTACGGTT
ATGCACCGGGCATCGAAACGACTACGGGCCCACTCGGCCAAGGCATCACCAATGCCGTAGGTATGGCGATTGCTGAGAAA
GCACTGGCGGCGCAGTTCAACAAACCGGGTCACGACATCGTTGACCACTTCACTTATGTGTTCATGGGTGACGGCTGTTT
GATGGAAGGTATCTCGCACGAAGCGTGTTCACTGGCGGGCACACTTGGCCTTGGCAAACTGATTGCGTTCTGGGATGACA
ACGGTATCTCTATCGACGGCCACGTGGAAGGCTGGTTCTCAGACGACACACCAAAACGTTTTGAAGCGTACGGCTGGCAC
GTAATCCCAGCGGTTGATGGTCACGATGCAGACGCGATTAATGCAGCAATTGAAGCGGCGAAAGCAGAAACCTCTCGCCC
AACGCTGATTTGTACCAAAACCATCATCGGTTTCGGCTCTCCAAACAAAGCGGGCTCACACGACTGTCACGGCGCGCCTC
TGGGCAACGATGAAATCAAAGCTGCACGTGAATTCTTGGGTTGGGAACACGCTCCGTTTGAAATCCCAGCGGACATCTAC
GCAGCGTGGGATGCAAAACAAGCAGGCGCAAGCAAAGAAGCCGCTTGGAATGAGAAATTCGCCGCTTACGCGAAAGCTTA
CCCAGCCGAAGCTGCTGAATACAAACGCCGCGTAGCGGGCGAGCTGCCAGCGAATTGGGAAGCCGCAACCAGCGAGATTA
TCGCTAACCTGCAAGCTAACCCTGCCAACATCGCATCGCGTAAAGCATCACAAAATGCGCTGGAAGCGTTCGGCAAACTG
CTGCCAGAATTTATGGGTGGTTCTGCTGACTTGGCGCCTTCTAACCTCACCATGTGGTCTGGCTCTAAGTCACTGACAGC
AGAAGATGCGTCAGGCAACTACATCCACTACGGTGTGCGTGAGTTTGGTATGACGGCCATCATCAACGGTATCGCGCTGC
ACGGCGGTTTTGTCCCTTACGGTGCAACCTTCCTGATGTTTATGGAATACGCGCGTAACGCGATGCGTATGGCAGCACTG
ATGAAAGTGCAAAATATCCAAGTGTACACGCATGACTCTATCGGTCTGGGTGAAGATGGCCCAACTCACCAACCAGTTGA
GCAAATCGCTTCTCTGCGTATGACACCAAACATGAGCACATGGCGCCCATGTGACCAAGTGGAATCGGCAGTGGCTTGGA
AACTGGCCATCGAGCGTAAAGATGCGCCATCTGCGCTGATTTTCTCGCGTCAAAACCTTGCGCAGCAACCACGCAGCGCA
GAGCAAGTCGCGAACATCGCTAAAGGCGGTTACATCCTGAAAGATTGTGCAGGCCAACCTGAGCTAATTCTGATTGCAAC
AGGCTCTGAAGTGGAACTGGCGGTTGCCGCTTACGAGCAACTGAGCGCCGAAGGTAAAGCGGTTCGCGTCGTTTCTATGC
CATCGACCGATGCGTTTGATAAGCAAGATGCGGCTTACCGTGAAGCCGTTCTGCCAGCCGCTGTGACTAAGCGTATCGCG
ATTGAAGCGGGCATTGCCGACTTCTGGTACAAGTACGTTGGCTTTGGTGGTCGCATCATCGGTATGACTAGCTTCGGTGA
ATCAGCACCAGCGGGTGAGCTGTTCAAACTGTTTGGTTTCACGACTGAAAACGTAGTGAAGCAAGCTAAAGAACTGCTGG
CGTAA

Protein sequence :
MQQQGGFATIAATDFPHPFISLTSHLGVDMSSRKQLANAIRALSMDGVQKANSGHPGAPMGMADIAEVLWRSHLNHNPQN
PNWADRDRFVLSNGHGSMLIYSLLHLSGYELSIDDLKNFRQLHSKTPGHPEYGYAPGIETTTGPLGQGITNAVGMAIAEK
ALAAQFNKPGHDIVDHFTYVFMGDGCLMEGISHEACSLAGTLGLGKLIAFWDDNGISIDGHVEGWFSDDTPKRFEAYGWH
VIPAVDGHDADAINAAIEAAKAETSRPTLICTKTIIGFGSPNKAGSHDCHGAPLGNDEIKAAREFLGWEHAPFEIPADIY
AAWDAKQAGASKEAAWNEKFAAYAKAYPAEAAEYKRRVAGELPANWEAATSEIIANLQANPANIASRKASQNALEAFGKL
LPEFMGGSADLAPSNLTMWSGSKSLTAEDASGNYIHYGVREFGMTAIINGIALHGGFVPYGATFLMFMEYARNAMRMAAL
MKVQNIQVYTHDSIGLGEDGPTHQPVEQIASLRMTPNMSTWRPCDQVESAVAWKLAIERKDAPSALIFSRQNLAQQPRSA
EQVANIAKGGYILKDCAGQPELILIATGSEVELAVAAYEQLSAEGKAVRVVSMPSTDAFDKQDAAYREAVLPAAVTKRIA
IEAGIADFWYKYVGFGGRIIGMTSFGESAPAGELFKLFGFTTENVVKQAKELLA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 0.0 79
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 0.0 69