Gene Information

Name : murD (VCM66_2326)
Accession : YP_002811077.1
Strain :
Genome accession: NC_012578
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : 6.3.2.9
Position : 2509244 - 2510647 bp
Length : 1404 bp
Strand : -
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
TTGGATCATCTCTATCGTTTTAGTATTGATTGGCTTAGCGACACTCAAAGTTCGTTAAGTGGATTAAGGATGTCAATTTC
AATGGACCGTTGGCAAGGCATACAACATGTGGTCGTCGTAGGGCTCGGGATTACCGGGCTCTCTGTCGTTAATTATCTGA
GAAAATATCATCCGTCGGTAACCGTGCAGGTTATCGATACGCGCGAAGCACCACCGGGGCAAGAGCAGCTTTCGTCGGAC
GTTGCACTGCATCGTAGCGGTTGGAATCTTGAGTGGTTACTCAATGCCGATTTGGTAGTCACCAACCCAGGCATTGCGTT
GGCGACGCCGGAAATCCAACAAGTGCTGGCCGCTGGAATTCCTGTTGTCGGTGATATTGAGCTCTTTGCATGGCATGTGG
ATACACCCGTTATTGCGATCACTGGCTCAAATGGCAAAAGCACCGTCACTGATTTAAGCGGTGTGTTAGCCAATGCTGCT
GGTGTGAAGGCCGCGGTAGGTGGCAATATTGGGGTTCCGGCACTGGATCTGATTTCTCCAGACGTTGAACTGTATGTGCT
TGAGCTATCAAGCTTCCAATTAGAAACTACCTCTAGCTTAAAACTGAAAGCGGCCGCGTTTCTCAATCTTTCTGAAGATC
ATATGGATCGTTATCAGGGGATGGAAGATTACCGCCAAGCCAAACTGCGCATTTTCGATCATGCCGAAACCGCAGTGGTG
AATGCCGATGATACTCAAACTTTTCCTGACCACGCGGCACATCTGCAAGTGGTGACGTTTGGTGTCGAGCAAGCTGCACA
ATTTAGCCTTGCTCAACATCAAGGCCGCGAATACCTTTTTGCGCGCGATGAGGCCGTCATGGCGTGTGCTGAGCTGAGTT
TAGTTGGCCGTCATAACGTGGCAAACGTACTTACCGTGTTAGCTTTGCTGGATTCAGCCGGAGTAAACTTCCGTTTGGCT
TTGGATGCACTCAAGTCTTACACAGGTTTGACACACCGCTGCCAAGTGGTTGCCGATAATCACGGCATCAAGTGGGTCAA
TGATTCTAAAGCGACCAATGTTGCGAGTACGCTGGCAGCATTGTCGGGATTAAAAATCGAAGGTCAGCTCTATTTGTTGG
TTGGTGGCGTAGGTAAAGGGGCGGATTTCACGCCGCTCGCCCCCGTATTGGCGACATTGCCTGTGCAATTGTGCTGCTTT
GGTGTGGACGGCCATCAATTTATGCCACTGCACCCTTCGGCTCGGTTTTATGACTCGATGGAGAGCATAATTCGCTCAAT
CCGCCCGCAATTAAAAAGTGGGGATATGGTGCTGCTCTCTCCCGCTTGTGCGAGCTTTGATCAGTTCAAAAACTTTATGG
CGCGTGGGGATATTTTTGCCCAACTCGCTCGGCAATATGCATAA

Protein sequence :
MDHLYRFSIDWLSDTQSSLSGLRMSISMDRWQGIQHVVVVGLGITGLSVVNYLRKYHPSVTVQVIDTREAPPGQEQLSSD
VALHRSGWNLEWLLNADLVVTNPGIALATPEIQQVLAAGIPVVGDIELFAWHVDTPVIAITGSNGKSTVTDLSGVLANAA
GVKAAVGGNIGVPALDLISPDVELYVLELSSFQLETTSSLKLKAAAFLNLSEDHMDRYQGMEDYRQAKLRIFDHAETAVV
NADDTQTFPDHAAHLQVVTFGVEQAAQFSLAQHQGREYLFARDEAVMACAELSLVGRHNVANVLTVLALLDSAGVNFRLA
LDALKSYTGLTHRCQVVADNHGIKWVNDSKATNVASTLAALSGLKIEGQLYLLVGGVGKGADFTPLAPVLATLPVQLCCF
GVDGHQFMPLHPSARFYDSMESIIRSIRPQLKSGDMVLLSPACASFDQFKNFMARGDIFAQLARQYA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 8e-55 42
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 8e-55 42