Gene Information

Name : CLM_0907 (CLM_0907)
Accession : YP_002803137.1
Strain : Clostridium botulinum Kyoto
Genome accession: NC_012563
Putative virulence/resistance : Resistance
Product : putative arsenite-transporting ATPase ArsA
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG0003
EC number : 3.6.3.16
Position : 965964 - 967709 bp
Length : 1746 bp
Strand : +
Note : identified by similarity to SP:P08690; match to protein family HMM PF02374; match to protein family HMM TIGR00345

DNA sequence :
ATGTTTAAAAAATTTAATGTGGAAGATATAAACTTAACAAAATATTTGTTCTTTACTGGCAAAGGTGGAGTTGGTAAGAC
TTCAACAGCTTGTGCCATAGCAGTGGCTTTAGCTGATAGCGGTAAAAAAATTATGCTTGTTAGTACAGATCCAGCTTCAA
ATCTTCAAGATGTATTTAATACAAAATTAAATAATAAGGGAGTTTATATAAAAGAAGTTCCTAATTTGGTAGTTGCAAAC
TTTGAACCAGAAGAAGCAGCTGCTGAATATAGAGAAAGCGTAATAGCACCTTATCGTGGAAAACTACCAGAAGTAGTTTT
GAAAAATATGGAGGAACAGCTTTCAGGTTCATGTACTGTTGAGATTGCTGCATTTAATGAATTTTCAACCTTTATAACTG
ATGAAAAAGTAGAAAAAGAGTATGATCATATTATATTTGATACAGCACCAACAGGCCATACACTAAGGATGTTGCAGCTT
CCTTCAGCATGGAGTAATTTTATTAATGAAAGTACACATGGTGCTTCATGTTTAGGACAGCTTTCAGGACTTGAAAGTAA
AAGAGAAGTTTATAAAAATGCAGTAAATACTCTAGCGGATAAGGATAAAACTACACTTATACTTGTATCACGTCCAGAAG
TATCACCTTTAAAGGAAGCTGAAAGAGCCTCTAAGGAACTTCAAGATATAGGTGTAAACAATCAAGTTTTAGTTATTAAT
GGAGTACTTGAAGAACATGAAGATTATCTTTCCAATGCTATTTATACTAAACAGCAAAAAGCATTAGAAGATATTCCAGA
ATCACTAAAGACTGTTGAAACTTTTCAAATTCCATTAAGACCGTATAATGTAACAGGTTTAGAAAATGTAAGAGCTTTTT
TAAGGAATAATAATATTAAATATAATGATGAAAAACTAAACACTACTAATATACCTAAATTAAATGAGGTAATAGAAGAT
TTATATAATACTGATAAAAAAGTAATATTTACAATGGGTAAAGGTGGCGTAGGTAAAACTACAATAGCTGCTGCAATAGC
TGTAGGACTAGCTAAAAAAGGGAAGAAAGTACATTTAACAACTACTGATCCGGCAGATCACTTAAAGTTTGTATTAGATG
AAGATTATGGAATTACTTTAAGCCATATAGATGAAAAAGAAGAACTAGAAAAATACAAAGAAGAGGTATTAAGTAAAGCA
CGAAAAACTATGAGTGAAGATGATATTGCTTATGTTGAAGAAGATCTAAGATCACCTTGTACTCAAGAAATTGCAGTATT
TAGGGCCTTTGCAGAAATAGTTGAAAGGTCAGAAAATGAGGTTGTAGTTATTGATACAGCACCAACAGGACATACTTTAT
TACTTTTAGACTCTACTCAAAGTTATAATAAAGAAATTCAACGTTCACAAGGAGATATTCCAGAATCAGTTAAGAAGCTT
TTACCTAAGCTTAGAAATGAGGAAAATACAGAAGTAATCATCGTAACACTAGCTGAAACAACTCCAGTTTATGAGGCTAT
GAGACTTCAAGAAGATTTGAATAGAGCTGGTATTCACAGTAAATGGTGGGTTATCAATTCAAGTTTTTATGTAGCTGATA
CAACAAATTCTATCTTAAAGGTAAAAGCCAACAATGAGGTACAGTGGATTAATAAAGTGAATGAAATATCTAAAGGTAAT
TTTGCAGTTATAGAGTGGATTCCTAAGGAAGTTAAAGGCGAAATACTTAATGATTTAATCAACTAG

Protein sequence :
MFKKFNVEDINLTKYLFFTGKGGVGKTSTACAIAVALADSGKKIMLVSTDPASNLQDVFNTKLNNKGVYIKEVPNLVVAN
FEPEEAAAEYRESVIAPYRGKLPEVVLKNMEEQLSGSCTVEIAAFNEFSTFITDEKVEKEYDHIIFDTAPTGHTLRMLQL
PSAWSNFINESTHGASCLGQLSGLESKREVYKNAVNTLADKDKTTLILVSRPEVSPLKEAERASKELQDIGVNNQVLVIN
GVLEEHEDYLSNAIYTKQQKALEDIPESLKTVETFQIPLRPYNVTGLENVRAFLRNNNIKYNDEKLNTTNIPKLNEVIED
LYNTDKKVIFTMGKGGVGKTTIAAAIAVGLAKKGKKVHLTTTDPADHLKFVLDEDYGITLSHIDEKEELEKYKEEVLSKA
RKTMSEDDIAYVEEDLRSPCTQEIAVFRAFAEIVERSENEVVVIDTAPTGHTLLLLDSTQSYNKEIQRSQGDIPESVKKL
LPKLRNEENTEVIIVTLAETTPVYEAMRLQEDLNRAGIHSKWWVINSSFYVADTTNSILKVKANNEVQWINKVNEISKGN
FAVIEWIPKEVKGEILNDLIN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SH0111 YP_252026.1 arsenical pump-driving ATPase Not tested SCCmec Protein 2e-121 47
arsA2 YP_001007632.1 arsenical pump-driving ATPase Not tested YAPI Protein 1e-118 46

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CLM_0907 YP_002803137.1 putative arsenite-transporting ATPase ArsA BAC0572 Protein 9e-118 46
CLM_0907 YP_002803137.1 putative arsenite-transporting ATPase ArsA BAC0571 Protein 2e-118 46
CLM_0907 YP_002803137.1 putative arsenite-transporting ATPase ArsA BAC0030 Protein 1e-116 46