Gene Information

Name : metC (CLM_0868)
Accession : YP_002803098.1
Strain : Clostridium botulinum Kyoto
Genome accession: NC_012563
Putative virulence/resistance : Resistance
Product : cystathionine beta-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.8
Position : 928954 - 930096 bp
Length : 1143 bp
Strand : -
Note : identified by match to protein family HMM PF01053; match to protein family HMM PF01212

DNA sequence :
ATGAAAATTGAATCATTATTAATTCATGGTGGAATAGATGGAGATAAGCATACAGGTGCAGTAAATGTACCTATTTATCA
AACTTCAACTTACAAGCAATTTAAGTTTGGAGAAAATACAGGTTATGAATATTCAAGAACAGGAAATCCAACAAGGGAAG
CTTTAGAAAAACTTGTAGCAGATTTAGAAAAAGGTTATAAAGGTTTTGCCTTTGCTTCAGGATTGGCTGCTATAACTGCA
GTATTATCACTATTTAAATCAGGAGATGAAATAGTAATTTCAAATAATGTATATGGTGGAACTTTTAGAGTTTTAGATAA
AGTCTTTAACCACTTTGATATTAAATATTCTATAGTTGATACTTCTAACTTAGATGAAGTAAAAAATAGCATAAATGAAA
ATGTAAAAGCTATATATATAGAAACACCAACTAATCCTCTTATGGATATTACAAATATAGAAGAAATATCAAAAATAGCT
AAGGAAAATGATATATATACTATAGTTGATAATACCTTCATGACCCCTTACCTACAGAAGCCAATAAGTCTTGGAGCAGA
TATAGTTATTCATAGTGCTACAAAATATCTAGGAGGGCATAGTGATGTAGTTGCTGGAATTGCTGTTGTAAATAGTGAAG
ATTTAGCTGAAAGACTTCATTTTATACAGAATTCTACTGGTGGGGTTCTAGCTCCTTTTGATTCTTTCCTTTTAATTAGA
GGAATCAAAACATTAGCAATAAGAATGGATAGACATAATTCAAATGCAAAACTTATTGCTGAATTCCTAAGAGAAAGAGA
TGAGGTAGTAAAAGTATATTATCCTGGTTTTCATACTCATCCAGGACATAAAATCCAATCAAAACAAGCTAATGGATATG
GTGGAATGATATCTTTTGTTCTTAAGGATGGTTATGATTATAAAAAGTTTTTTGAAGGTCTTAAGATGGTAACCTTTGGA
GAAAGCTTAGGAGGAGTTGAATCTTTAGCTTGCCATCCAGCTTCTATGACTCACGGTGCTATACCTTATGAATTAAGACA
AAAAGTTGGTATTGTAGATAATTTAATAAGATTATCCGTTGGTATAGAAAATGCTGACGATTTAATAGAAGATTTAAAAA
ATGCATTTAAGGAGAGTAGATAA

Protein sequence :
MKIESLLIHGGIDGDKHTGAVNVPIYQTSTYKQFKFGENTGYEYSRTGNPTREALEKLVADLEKGYKGFAFASGLAAITA
VLSLFKSGDEIVISNNVYGGTFRVLDKVFNHFDIKYSIVDTSNLDEVKNSINENVKAIYIETPTNPLMDITNIEEISKIA
KENDIYTIVDNTFMTPYLQKPISLGADIVIHSATKYLGGHSDVVAGIAVVNSEDLAERLHFIQNSTGGVLAPFDSFLLIR
GIKTLAIRMDRHNSNAKLIAEFLRERDEVVKVYYPGFHTHPGHKIQSKQANGYGGMISFVLKDGYDYKKFFEGLKMVTFG
ESLGGVESLACHPASMTHGAIPYELRQKVGIVDNLIRLSVGIENADDLIEDLKNAFKESR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-90 51
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 9e-92 51
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-67 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metC YP_002803098.1 cystathionine beta-lyase BAC0207 Protein 4e-72 45