Gene Information

Name : CLM_0827 (CLM_0827)
Accession : YP_002803059.1
Strain : Clostridium botulinum Kyoto
Genome accession: NC_012563
Putative virulence/resistance : Resistance
Product : macrolide export ATP-binding/permease MacB
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1136
EC number : 3.6.3.-
Position : 888954 - 889637 bp
Length : 684 bp
Strand : +
Note : identified by match to protein family HMM PF00005

DNA sequence : 
ATGAATTTATTGGAAGTTAAATCAATTTCTAAAACCTATGGCAGCGGTGAAGCTGCCGTACATGCATTAAAAGATATCAG
CTTTTTCGTTCCGAAAGGCGAATTTGTTGCAATAGTCGGGGAATCAGGCTCCGGTAAGAGTACACTTCTGAATATGATAG
GGGCGCTTGATATGCCCACCTCCGGCAAAGTATTTATTGACGGTAAAGATATTTTTTCAATGAAAGATAGTAATTTGACA
ATCTTTAGGCGTAGAAATATTGGATTTATTTTTCAGAATTTTAATCTAATTCCAGAATTGAATGTTGAGCAAAACATCAT
ATTTCCCGTACTGCTTGATTATCAAGAGCCCGATAAAAAGTATCTTGAGGAACTGCTTACTGTGCTTAATTTGAAAGAAC
GCCGTCACCATTTACCCAGTCAATTATCAGGTGGCCAGCAACAGCGTGTAGCAATAGGACGTGCACTAATTACGCGGCCT
TCACTTATCCTTGCCGATGAGCCGACGGGTAATTTAGATACGCAAAACAGCAGTGAAGTGATTACTTTGCTAAAAGAAGC
TGCAAGAAAGTACCAGCAGACCATTGTTATGATTACCCATAGCCGAAGTATCGCACAGACTGCAGATCGAATAATACAAG
TGTCTGATGGTATACTGACCGATTTAGGGAGGTGCCGCGAATGA

Protein sequence : 
MNLLEVKSISKTYGSGEAAVHALKDISFFVPKGEFVAIVGESGSGKSTLLNMIGALDMPTSGKVFIDGKDIFSMKDSNLT
IFRRRNIGFIFQNFNLIPELNVEQNIIFPVLLDYQEPDKKYLEELLTVLNLKERRHHLPSQLSGGQQQRVAIGRALITRP
SLILADEPTGNLDTQNSSEVITLLKEAARKYQQTIVMITHSRSIAQTADRIIQVSDGILTDLGRCRE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
Cp1002_1464 YP_005681730.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 9e-38 45
CpC231_1466 YP_005683828.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 2e-38 44
cpfrc_01473 YP_003783873.1 hypothetical protein Not tested PiCp 5 Protein 2e-38 44
CpI19_1473 YP_005685914.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 2e-38 44
unnamed AAP55232.1 unknown Not tested SaPIbov2 Protein 1e-38 43
SARLGA251_00480 YP_005754062.1 ABC-type transport system ATPase Not tested Type-XI SCCmec Protein 8e-33 41
Spaf_1862 YP_006310627.1 amino acid ABC transporter ATP-binding protein Not tested FWisland_2 Protein 5e-26 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CLM_0827 YP_002803059.1 macrolide export ATP-binding/permease MacB CP001581.1.gene798.p Protein 4e-105 100
CLM_0827 YP_002803059.1 macrolide export ATP-binding/permease MacB CP001581.1.gene598.p Protein 6e-58 54
CLM_0827 YP_002803059.1 macrolide export ATP-binding/permease MacB NC_012469.1.7686878. Protein 3e-43 46
CLM_0827 YP_002803059.1 macrolide export ATP-binding/permease MacB NC_008702.1.4606598. Protein 2e-35 42