Gene Information

Name : CLM_0622 (CLM_0622)
Accession : YP_002802864.1
Strain : Clostridium botulinum Kyoto
Genome accession: NC_012563
Putative virulence/resistance : Resistance
Product : macrolide export ATP-binding/permease MacB
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1136
EC number : 3.6.3.-
Position : 673759 - 674424 bp
Length : 666 bp
Strand : +
Note : identified by match to protein family HMM PF00005

DNA sequence :
ATGAGTATTTTACAGACAACTAATTTAAAAAAATATTATGGGAAAGAGCCCAACCTTGTGAAAGCTCTAGATGGAGTAAG
TATTACCATTGAAAAGGGAGAGTTTGTATCCGTAGTAGGTACATCTGGAAGTGGTAAATCTACTTTGCTTCATATGATGG
GAGGATTAGATAATCCTACATCTGGAAGTGTTATTGTAAGGGATAAAGAGCTTTCTAATATGAATAAAGAGGAACTTGTT
ATTTTTAGACGCCGGAATATAGGATTTATTTTTCAAAGTTACAATTTAGTACCTATGCTTAATGTTTATGAAAATATTGT
TTTGCCTCTAGAACTAGATGGAGAATCTGTAGATAAGTCTTTTCTGAATAAAATTGTTAAAATTCTAGCTTTAGAAGATA
AGCTACAAAATATGATAAACAATCTTTCAGGTGGTCAGCAGCAGCGTGTAGCCATTGCAAGAGCTTTGCTTACAAAACCT
GCCATTATTCTTGCAGATGAACCTACAGGAAACTTAGATAGTAAAACAAGTGCTGATGTAATGGGACTTTTAAAAATGAC
CAGTAAAAAATTTAGTCAAACTATTGTAATGATTACTCATAACAATGAAATTGCTCAGCTTGCTGATAGAATCATTCGTA
TTGAAGACGGTAAAGTTATGGTCTAA

Protein sequence :
MSILQTTNLKKYYGKEPNLVKALDGVSITIEKGEFVSVVGTSGSGKSTLLHMMGGLDNPTSGSVIVRDKELSNMNKEELV
IFRRRNIGFIFQSYNLVPMLNVYENIVLPLELDGESVDKSFLNKIVKILALEDKLQNMINNLSGGQQQRVAIARALLTKP
AIILADEPTGNLDSKTSADVMGLLKMTSKKFSQTIVMITHNNEIAQLADRIIRIEDGKVMV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
Cp1002_1464 YP_005681730.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 3e-29 42
Spaf_1862 YP_006310627.1 amino acid ABC transporter ATP-binding protein Not tested FWisland_2 Protein 4e-21 41
CpC231_1466 YP_005683828.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 3e-30 41
cpfrc_01473 YP_003783873.1 hypothetical protein Not tested PiCp 5 Protein 3e-30 41
CpI19_1473 YP_005685914.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 3e-30 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CLM_0622 YP_002802864.1 macrolide export ATP-binding/permease MacB CP001581.1.gene598.p Protein 2e-95 100
CLM_0622 YP_002802864.1 macrolide export ATP-binding/permease MacB CP001581.1.gene798.p Protein 5e-53 54
CLM_0622 YP_002802864.1 macrolide export ATP-binding/permease MacB NC_012469.1.7686878. Protein 4e-31 42
CLM_0622 YP_002802864.1 macrolide export ATP-binding/permease MacB NC_008702.1.4606598. Protein 1e-27 41