Gene Information

Name : clpB (CLM_0480)
Accession : YP_002802734.1
Strain : Clostridium botulinum Kyoto
Genome accession: NC_012563
Putative virulence/resistance : Virulence
Product : clpB protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 519037 - 521637 bp
Length : 2601 bp
Strand : +
Note : identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR03346

DNA sequence :
ATGAATATTGAAAAATTAACTTTAAAGGTACAGCAAGCTATAAATGATTCTCAACTTGTTGCAGTTAAGTATAATCATCA
GCAGATTGATACTATACATTTATTTTCAGCCTTAATTTCTCAAGATGATGGATTAATTCCTAATATTTTAGGGAAAATGG
GAGTGAATATAAGAGATATTAATGCTGAAACCAATAGGGTCTTAGATAATATGCCTAAAGTATTAGGTGAGGGAGCACAG
TCATCTTCTGTGTATCCTACTAGAAGGTTTGAAGAGGTTTTTGTAAAGGCAGAACAGATAGCAAAGGATTTTAAAGATTC
ATATATAAGTGTAGAACATGTTTTATTAGCAATAATGGATGTGGATAGAAATACTGTTTTTCCTATATTAGAAAAATTTG
GAGTAAAAAAATCAGAGTTTTTAAAGGCATTATCAGCTGTTAGAGGAAGTCAAAGAGTTGATAGTCAAGATCCAGAGGGG
ACTTATGAAGCTTTGGTTAAGTATGGTAGAAATTTAGTTGAAGAAGCTAAGAAACATAAATTGGATCCTGTTATAGGTAG
AGATGAAGAAATAAGAAGAGTTGTAAGAATTTTATCTAGAAGAACTAAGAATAATCCTGTTCTTATTGGAGAACCAGGTG
TAGGTAAGACTGCTATTGTAGAGGGATTAGCAGAGAGAATTGTTAGAGGAGATGTACCAGAAAGTTTAAAAAATAAAATA
ATATTTTCTTTAGATATGGGGGCACTTATTGCAGGTGCAAAATATAGAGGAGAATTTGAAGAAAGATTAAAAGCAGTATT
AAAAGAAGTTCAAAATAGTGAGGGAAGGATAATTTTATTTATAGATGAAATCCATACTATAGTAGGGGCAGGAAAAACAG
AGGGATCTATGGATGCAGGAAATTTAATAAAACCTATGCTTGCCAGAGGAGAACTTCATTGTATTGGAGCTACTACCTTT
GATGAATATAGACAGTATATAGAAAAAGACAAAGCTTTAGAAAGAAGATTTCAACCTGTAATAACAGATGAGCCTACAGT
AGAGGATACAGTATCTATATTAAGAGGGCTTAAAGAAAGATTTGAAATATATCATGGAATAAGAATACATGATTCAGCTA
TTGTAGCTGCAGCTAAGCTCTCTAGTAGATATATTACAGATAGATATCTCCCAGACAAGGCAATAGATTTAATAGATGAA
GCTTGTGCTATGATAAGAACAGATATAGATAGTATGCCAACGGAAATGGATTCAATGAAAAGAAAAATATTTCAATTAGA
AATAGAAAAGGAAGCATTGTCTAAAGAAAAAGATGTGGCTTCAAAGGAAAGATTAGAAGTTTTAGAAAAGGAATTGAGTG
AACTAAAAGAGAAAGATAAAGAAATGACAGCCAAGTATGAAAATGAAAAATCTCATATAACAAAAATAAGAGATTTAAAA
GAAAAATTGGATGATGTTAGAGGTCAGATGGAAAAGGCCGAAAGAGAATATGATTTGAATAAAGTTGCAGAATTAAAATA
TGGTTTAATACCAGCTCTTCAAAGAGAAATAGAAGAAAAAGAGAAATTAATAAAGGAAAATAGTAACGGAAATGCTATGT
TAAAAGAAGAGGTTACAGAGCAAGAAATTTCTGAAATAATCTCTAAATGGACTGGTATACCTGTAACAAGATTAGTTGAA
ACTGAAAGACAAAAACTATTACAATTAGGAGATCAATTAGAAACTAGAGTAATAGGTCAAGGAGAGGCAGTAAAAGCAGT
AACTAATGCAGTTATAAGAGCTAGAGCAGGACTAAAAGATCCAAGAAAACCTATAGGATCATTTATATTCTTAGGACCTA
CAGGTGTAGGAAAGACAGAACTTGCAAAAACTTTGGCCAGAACTTTATTTGATACTGAAGAAAATATTATAAGAATAGAT
ATGTCTGAATATATGGAAAAATATTCAGTATCAAGACTTATAGGAGCTCCTCCAGGATATGTAGGATATGAAGAAGGAGG
CCAGCTAACAGAAGCCGTTAGGAGAAAGCCTTATAGTGTTATATTATTTGATGAAATAGAAAAAGCTCATGACGATGTAT
TTAACATATTCCTTCAAATATTAGATGATGGAAGACTTACAGACAATAAGGGGAAGGTTATAGATTTTAAAAATACTATA
ATTATAATGACTTCTAATTTAGGAAGTAACTATTTATTAGATAATGAAAGCAAAGAAGGCATTGATGAAAGTATAAGAAC
AAGAGTAAAAGAGGCTTTAAAGGCTAGATTTAAACCAGAATTTTTAAATAGAGTAGATGACATTATAATGTTTAAACCTC
TTACGGTAGAAGACATTAAGAGAATAATAGATATATTCTTAGATGATATAAGAAAAAGACTTAAAGATAAGAATATACAG
CTTAAAATTACTGATAGTGCAAAAGATATAATGGCCAAAGAAGGTTATGATCCAATATATGGCGCAAGGCCGCTAAAGAG
ATATATAGAAGATACTATAGAAACAGAAATAGCAAAACAAATAATAGCAGGTAATATATATGAAGGTACTACTGTAGGAG
TAGACTTAAAAGGAGAGTCAATAGTTATAGAAAGAATATAA

Protein sequence :
MNIEKLTLKVQQAINDSQLVAVKYNHQQIDTIHLFSALISQDDGLIPNILGKMGVNIRDINAETNRVLDNMPKVLGEGAQ
SSSVYPTRRFEEVFVKAEQIAKDFKDSYISVEHVLLAIMDVDRNTVFPILEKFGVKKSEFLKALSAVRGSQRVDSQDPEG
TYEALVKYGRNLVEEAKKHKLDPVIGRDEEIRRVVRILSRRTKNNPVLIGEPGVGKTAIVEGLAERIVRGDVPESLKNKI
IFSLDMGALIAGAKYRGEFEERLKAVLKEVQNSEGRIILFIDEIHTIVGAGKTEGSMDAGNLIKPMLARGELHCIGATTF
DEYRQYIEKDKALERRFQPVITDEPTVEDTVSILRGLKERFEIYHGIRIHDSAIVAAAKLSSRYITDRYLPDKAIDLIDE
ACAMIRTDIDSMPTEMDSMKRKIFQLEIEKEALSKEKDVASKERLEVLEKELSELKEKDKEMTAKYENEKSHITKIRDLK
EKLDDVRGQMEKAEREYDLNKVAELKYGLIPALQREIEEKEKLIKENSNGNAMLKEEVTEQEISEIISKWTGIPVTRLVE
TERQKLLQLGDQLETRVIGQGEAVKAVTNAVIRARAGLKDPRKPIGSFIFLGPTGVGKTELAKTLARTLFDTEENIIRID
MSEYMEKYSVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSVILFDEIEKAHDDVFNIFLQILDDGRLTDNKGKVIDFKNTI
IIMTSNLGSNYLLDNESKEGIDESIRTRVKEALKARFKPEFLNRVDDIIMFKPLTVEDIKRIIDIFLDDIRKRLKDKNIQ
LKITDSAKDIMAKEGYDPIYGARPLKRYIEDTIETEIAKQIIAGNIYEGTTVGVDLKGESIVIERI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 1e-158 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_002802734.1 clpB protein VFG2076 Protein 3e-113 41
clpB YP_002802734.1 clpB protein VFG2084 Protein 4e-103 41