Gene Information

Name : dnaB (CLM_4125)
Accession : YP_002806163.1
Strain : Clostridium botulinum Kyoto
Genome accession: NC_012563
Putative virulence/resistance : Unknown
Product : replicative DNA helicase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0305
EC number : 3.6.1.-
Position : 4131157 - 4132494 bp
Length : 1338 bp
Strand : -
Note : unwinds double stranded DNA

DNA sequence :
ATGGATGCACCCATAAAAAGTATGCCGCAGAGTATAGATGCAGAGCAAAATGTATTAGGGGCAATGATTATAGATAAAAC
TTCCATAGCAGAGGCTGTGGAAGTTTTAAAAAGTGAAGATTTTTATAAAGATTCTCATAAAATTATATTTAGTGGAATTA
TAGAGCTTTATCAAAAGGATATAGCAGTAGATATGCTAACTCTTACGGAAAATCTTAAGTCACGAGATAAACTAGATGCA
GTAGGTGGGGTTACTTATATAACGGAGCTTTGTAACTCTATAGTTTCTACAGCTAATATTCAGTCTTATATAGATATAAT
AAAGGATAAATCTACATTAAGAAGGCTTATAAAGTCATCTACTGAAATAATAGAGAACTGTTATAACAGACAGGATAATG
TAGAAGAAATAATAGATTCTGCAGAGAAAAAAATATTTCACATATCCAACCAAAATACTACAACTGATTTTGAACCATTA
AGTAATGTTTTGGAAAGAGGATTTATTCAAATTGAAAACTTATTTAAAAATAAAGGTGAAACTACAGGGGTTGCATCTGG
TTTTAGAGAACTAGACGCTAAAACCTCAGGTTTTCAAAAGTCTGATATGATATTAATAGCAGCAAGACCATCAATGGGTA
AAACTACATTTGCTCTAAACATAGCAGAATATGCAGCTCTTAGAGAGGGAAAAAGTGTAGCAATCTTTTCCCTGGAAATG
TCAAAAGAGCAACTTTCTTATAAATTGCTTTGTTCCCAAGCTAATATTGATATGTTGAGGCTTAGAACTGGTAACTTAGA
GGATAAAGACTGGGAGAATATAGCTAGGGTTTCAGGGCCTTTAGCAGCAGCAAAGATATTTATAGATGATACTGCAGGTA
TGTCTGTAATGGAAATGCGTTCTAAATGTAGGAGATTAAAAATAGAACATGGAATAGATATGGTTTTAATAGATTATCTT
CAGCTTATGAGTGGAGGTAAAGGGTCTACTGAAAGTAGACAACAAGAAGTCTCAGAAATATCTAGATCTATAAAAGCCTT
AGCTAAAGAAATGGATTGTCCAGTTATAGCCTTATCTCAATTATCTCGTGCTCCGGAGGCTAGATCGGATCATAGACCAA
TGCTTTCAGATCTTAGAGAATCTGGATCTATAGAACAGGATGCTGACGTAGTTATGTTTTTATATAGAGATGAATACTAT
GACAAAGAAACAGAAGATAAAAACATGGCAGAATGCATTATAGCCAAGCAAAGAAATGGTCCTACGGGTACAGTTAAAAT
GGCATGGCTTGGACAATACAGTAAATTTGGTAATTTAGATGTGATACATCAAGAATAA

Protein sequence :
MDAPIKSMPQSIDAEQNVLGAMIIDKTSIAEAVEVLKSEDFYKDSHKIIFSGIIELYQKDIAVDMLTLTENLKSRDKLDA
VGGVTYITELCNSIVSTANIQSYIDIIKDKSTLRRLIKSSTEIIENCYNRQDNVEEIIDSAEKKIFHISNQNTTTDFEPL
SNVLERGFIQIENLFKNKGETTGVASGFRELDAKTSGFQKSDMILIAARPSMGKTTFALNIAEYAALREGKSVAIFSLEM
SKEQLSYKLLCSQANIDMLRLRTGNLEDKDWENIARVSGPLAAAKIFIDDTAGMSVMEMRSKCRRLKIEHGIDMVLIDYL
QLMSGGKGSTESRQQEVSEISRSIKALAKEMDCPVIALSQLSRAPEARSDHRPMLSDLRESGSIEQDADVVMFLYRDEYY
DKETEDKNMAECIIAKQRNGPTGTVKMAWLGQYSKFGNLDVIHQE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY4522 NP_458617.1 DNA helicase Not tested SPI-7 Protein 2e-72 42
t4227 NP_807829.1 DNA helicase Not tested SPI-7 Protein 2e-72 42
PMI2640 YP_002152342.1 DNA helicase Not tested Not named Protein 7e-75 41
unnamed ABR13456.1 replicative DNA helicase Not tested PAGI-5 Protein 9e-84 41
dnaB2 YP_001007676.1 putative DNA helicase Not tested YAPI Protein 5e-79 41
dnaB2 YP_001402701.1 replicative DNA helicase Not tested YAPI Protein 2e-80 41
api2 CAF28476.1 putative DNA binding protein with DNA-dependent ATPase activity Not tested YAPI Protein 8e-81 41