Gene Information

Name : thiC (CLM_3307)
Accession : YP_002805432.1
Strain : Clostridium botulinum Kyoto
Genome accession: NC_012563
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 3340010 - 3341323 bp
Length : 1314 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAATTATACAACTCAAATGGATGCTGCTAAAAAAGGAATAGTTACAAAAGAGATGGAAATAGTAGCTAAAAAGGAAAA
TATGAATGTGAAAGACCTTATGGAATTGGTATCTAAAGGTAAGGTTGCTATACCTGCTAATAAAAATCATAAATCTTTAG
ATCCAGAAGGAATAGGACAAGGTTTAAGAACTAAAATAAATGTCAATTTAGGAATATCTAAAGATTGCTATAATATAGAT
ATGGAATTAGAAAAAGTACAAAAAGCAATAGATATGAAGGCAGAGGCTATAATGGATTTGAGCTGCTTTGGAAAAACAGA
AGAATTTAGAAAAAGATTGATAGACATGTCACCAGCCATAATAGGTACTGTTCCTATATATGATGCAGTAGGTTTCTATG
ATAAAGAATTAAAAGATATTACATCAGAAGAATTTTTAAAGGTAGCAGAGAAGCATGCAGAGAATGGAGCAGACTTTTTA
ACAATACATGTAGGTATGAATAGAAAAACTGCAGCTACATTTAAGAAAAATCCAAGAACAATGAACATAGTTTCAAGAGG
AGGATCCCTTTTATATGCATGGATGGAACTAAATAATAAAGAAAATCCATTCTATGAAGGATTTGATAAACTTTTAGATA
TATGTGAAAAGTATGATGTTACATTAAGCTTAGGGGATGCTTGTCGTCCAGGTTGTATAGAGGATTCTACAGATGCAAGC
CAGATAGAAGAACTTATAGCTTTAGGGGAACTTACTAAAAGAGCCTGGGAGAGGAATGTACAAGTTATAATAGAGGGACC
AGGACACATGACTTTAGATGAAATAGAAATAAATATGAAAATAGAGAAAAAATTATGTCATGGAGCTCCGTTCTATGTTT
TAGGACCAATAGTTACAGATATAGCTCCAGGTTATGATCACATAACTTCAGCTATAGGTGGTGCTATTGCAGCAACTCAT
GGTGCAGATTTCTTATGCTATGTAACTCCAGCAGAACATTTAAGATTACCGAACTTAGATGATATGAAGGAAGGTATAAT
AGCATCAAAGATAGCAGCTCATGCAGCAGATTTAGCTAAAGGAGTAAAAGGAGCAAGAGATTGGGATAATGCTATGGCTA
AAGCTAGAAGAGATTTAGACTGGGAAAGAATGTTTGAGTTATCTATAGATGAAGAAAAAGCTAGAAGATATAGAGAAGAA
TCTAAGGCAAAAAGTAAAGATTCTTGTACAATGTGCGGAAAAATGTGTGCAGTAAGAAATATGAACAGAGTTACAGAAGG
AAAAGACTTAAACATGTTAAGAGATGATGATTAA

Protein sequence :
MNYTTQMDAAKKGIVTKEMEIVAKKENMNVKDLMELVSKGKVAIPANKNHKSLDPEGIGQGLRTKINVNLGISKDCYNID
MELEKVQKAIDMKAEAIMDLSCFGKTEEFRKRLIDMSPAIIGTVPIYDAVGFYDKELKDITSEEFLKVAEKHAENGADFL
TIHVGMNRKTAATFKKNPRTMNIVSRGGSLLYAWMELNNKENPFYEGFDKLLDICEKYDVTLSLGDACRPGCIEDSTDAS
QIEELIALGELTKRAWERNVQVIIEGPGHMTLDEIEINMKIEKKLCHGAPFYVLGPIVTDIAPGYDHITSAIGGAIAATH
GADFLCYVTPAEHLRLPNLDDMKEGIIASKIAAHAADLAKGVKGARDWDNAMAKARRDLDWERMFELSIDEEKARRYREE
SKAKSKDSCTMCGKMCAVRNMNRVTEGKDLNMLRDDD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 9e-69 45
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 9e-69 45
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 4e-66 42