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Name : leuS (CLM_0234) Accession : YP_002802498.1 Strain : Clostridium botulinum Kyoto Genome accession: NC_012563 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 218397 - 220838 bp Length : 2442 bp Strand : - Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGGGAAACTATAGTACTAAAATCGATGAGAAATGGCAAAAAAAATGGGAAGAAAACTCTCTATACAAATTTAATAATGA AAATTTAGATAAAAAGTTATATGTACTTGAAATGTTTTCTTATCCATCAGGTAGTAAATTACATGCAGGACACTGGTTTA ACTATGGGCCTGTAGACTCTTGGGCAAGATTTAAAAGAATGCAAGGTTACAATGTTTTTCAACCTATGGGGTTTGATGCT TTTGGTCTTCCAGCTGAAAACTATGCAATAAAAACTGGTATACATCCAAAGGATTCTACCTTTAAAAATATTGAAACTAT GGAAACTCAATTAAAAGCCATGGGTGCCATGTTCAACTGGGAAAATGAAGTTATAACTTGTTCACCAGACTACTATAAAT GGACTCAATGGTTATTTTTAAAACTTTACGAAAAAGGTTTAGCTTATAAAAAGAAAGCACCTGTAAATTGGTGCCCAAGT TGTAATACTGTTCTTGCTAATGAGCAGGTTTTAGATGGAAAATGTGAAAGATGTGATAGCAATGTTGATAAAAAAAATCT AGAGCAATGGTTCTTAAAGATAACTGACTATGCTGATGAATTGTTAGAAAAACTCGATGAATTAGATTGGCCTGAAAAAA CTAAGGCTATGCAAAAACACTGGATCGGAAAATCTGTAGGTGCTGAAGTTGCATTTAATGTAGCAGATTCAGACTTGAGC TTTAATGTATTTACTACAAGGGTAGATACTTTATTTGGAGTTACTTATGTAGTCTTAGCTCCTGAAAATGATTTAGTAGA TAAGCTAACTACCCCTGAAAATAAAGCCGAAGTTGAATCATATAAAACTCAAGCTAAAAATCAATCTGATATAGAAAGAC AATCTATAACTCGAGAAAAAACTGGTGTATTCTCAGGTTCTTATGCCATAAATCCTATAAACGGTAAAAAAGTACCTATA TGGATAGGAGATTATGTATTAAATACCTATGGAACAGGTTGTGTAATGGCAGTTCCTGCCCATGATGAAAGAGATTTCGC TTTTGCTACTAAATATAACCTTCCTATAGAAAGAGTTATAGAAGGTGGTGATTCTCTCCCTTATACAGAATATGGTAAAA TGGTTAATAGTGGAGAATTCGATGGTTTATTTGGAAATAAAGCTAAAGAAGCTGTAATTTCTAAGTTAGAGTCTATGAAT CTTGGTAGAAAGAAAATAAATTATAGATTAAGAGATTGGCTTGTATCAAGACAAAGATATTGGGGGGCACCTATTCCTAT AGTTTATTGCGAAAAATGTGGTACAGTAGAAGTTCCTATGGAACAGCTTCCTGTAGAATTACCATATAATGTACAATTCT CTCCAGATGGAAAATCACCTTTAAGTAAATGTGATGAATTTGTAAATACAACTTGTCCAAAATGTGGTGGTCCAGCTAAA AGGGAAGCAGATACATTAGACACTTTTGTATGTTCTTCTTGGTATTATCTAAGATATCCAGATAATAAAAACAGTGAAGC TGCTTTTAATCCTGAATTAATTAATAAAATGCTTCCAGTTGATAAATATGTTGGTGGTCCTGAACATGCTTGCATGCATC TTTTATATGCTAGATTTATAACTAAAGCTTTAAGAGATATGGGTTATCTAAACTTTGATGAACCATTCTTATCCCTTACT CACCAAGGATTAATATTAGGACCTGATGGCTTAAAAATGAGTAAATCAAAAGGAAATACTATATCTCCTGATGATTATAT AAAAGAATTTGGTGCAGATGTATTTAGAATGTATTTAATGTTTGGATTTGATTATACAGAAGGCGGCGCTTGGAGTGACG ATGCTATAAAATCCATAGGTAAATTTGTAGACAGAGTAGAAAGAATATTAGAAAATGCTAGAGAAGAAATAAAAAATTCT AAAGATAATAAATCTACTATGGATAAAGATGAGAAAGAATTAAACTACGTAAGGCATCATAGCATTAAATCTATAACTGA AGATATAGATAAAATGCAGTTCAATACTTCCATAGCAAGATTAATGGAATTTACAAATGCTCTATCTAAATATCTTGGTA TTGATGCTATTAAAAATGCTTTATTCTTGAGAGAAAGTATAATTGACTTTATAACATTATTAGCACCTTTTGCTCCTCAT TTTGCTGAAGAACAATGGGAACTTATAGGCATTAATTCTTCCATTTTCAATGAAAAATGGCCTGAATTTGACCCTAAAGC CCTAATAAAAGATGAAGTTGAAATAGCCGTACAAGTAAATGGGAAAATAAGAGCTAAAATAAATATATCTACTAGTTCAT CAGAAGATGAAATAAAAGAATCAGCATTAAATAATGAGGATATTAAAAATTCTATAGGTGATAAAGAAATTAAAAAAGTT ATAGTAATAAAAAATAGATTAGTTAATATAGTTGCTAAATAA Protein sequence : MGNYSTKIDEKWQKKWEENSLYKFNNENLDKKLYVLEMFSYPSGSKLHAGHWFNYGPVDSWARFKRMQGYNVFQPMGFDA FGLPAENYAIKTGIHPKDSTFKNIETMETQLKAMGAMFNWENEVITCSPDYYKWTQWLFLKLYEKGLAYKKKAPVNWCPS CNTVLANEQVLDGKCERCDSNVDKKNLEQWFLKITDYADELLEKLDELDWPEKTKAMQKHWIGKSVGAEVAFNVADSDLS FNVFTTRVDTLFGVTYVVLAPENDLVDKLTTPENKAEVESYKTQAKNQSDIERQSITREKTGVFSGSYAINPINGKKVPI WIGDYVLNTYGTGCVMAVPAHDERDFAFATKYNLPIERVIEGGDSLPYTEYGKMVNSGEFDGLFGNKAKEAVISKLESMN LGRKKINYRLRDWLVSRQRYWGAPIPIVYCEKCGTVEVPMEQLPVELPYNVQFSPDGKSPLSKCDEFVNTTCPKCGGPAK READTLDTFVCSSWYYLRYPDNKNSEAAFNPELINKMLPVDKYVGGPEHACMHLLYARFITKALRDMGYLNFDEPFLSLT HQGLILGPDGLKMSKSKGNTISPDDYIKEFGADVFRMYLMFGFDYTEGGAWSDDAIKSIGKFVDRVERILENAREEIKNS KDNKSTMDKDEKELNYVRHHSIKSITEDIDKMQFNTSIARLMEFTNALSKYLGIDAIKNALFLRESIIDFITLLAPFAPH FAEEQWELIGINSSIFNEKWPEFDPKALIKDEVEIAVQVNGKIRAKINISTSSSEDEIKESALNNEDIKNSIGDKEIKKV IVIKNRLVNIVAK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 3e-169 | 46 |
