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Name : secA (CLM_0221) Accession : YP_002802486.1 Strain : Clostridium botulinum Kyoto Genome accession: NC_012563 Putative virulence/resistance : Unknown Product : preprotein translocase subunit SecA Function : - COG functional category : U : Intracellular trafficking, secretion and vesicular transport COG ID : COG0653 EC number : - Position : 201710 - 204217 bp Length : 2508 bp Strand : + Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap DNA sequence : ATGGGAATTTTAAATAAAATATTTGGTACATATAGTGAAAGAGAACTTAGAAGAGTTAACCCTATAGTAAACAAAATAGA AGCTTTAGATGAAAAAATGCAATCCTTAAAAGATGAAGATTTTAAGCTAAAAACTGAAGAATTTAAAAGTAGATTAGAAA AAGGGGAAAAACTAGATGATATTTTACCAGAAGCTTTTGCCTTAGTTAGAGAAGCGGCACATAGAACCATAGGACTTAAA CATTATAGAGAACAATTAATAGGCGGTGTAGTATTACACCAAGGAAGAATTGGAGAAATGAAAACCGGTGAAGGTAAAAC TTTAGTTGCTACATTGCCAGCCTATGTAAATGCATTAACAGGAAAAGGGGTACATATAGTTACAGTTAATGATTACTTGG CAAAAAGAGATAGGGATTTAATGGCTCCGGTATATGAATTTTTAGGGCTAAAAGTAGGAGTTATTTTGCATAATTTAAAT AATGAAGAAAGACAAGAAGCTTATGGTTCAGATATAACTTATGGAACAAATAGTGAATTTGGCTTTGATTATTTAAGAGA TAATATGGTAGTTTATAAAGAAGAAAGAGTTCAAAGAAAGTTAAACTTTTCAATTGTGGATGAAGTGGACTCTATATTAA TAGATGAAGCTAGAACTCCATTAATAATATCAGGTCAAGGGGAGAAGTCTACAGAGTTTTATAAGGTTGCAGATTATTTC ACTAAATCTCTAATAGCTGAAAAAGATTTTACAATAGATGAAAAAGCTAATTCAGCTATGCTTACAGATGAAGGTGTTAA TAAAGCAGAGAATTTCTTTAAAGTAGATAACTATGCTGATGCAGAAAACATGGAAATACAACACCATGTAGTTCAAGCTT TAAAAGCTAACTATGTAATGAAAAAAGATAAAGATTATATGATTAAGGATGGAGAAATTCTAATAGTTGATGAGTTTACA GGAAGAGCTATGGAAGGAAGAAGATATAGCGATGGATTGCACCAAGCTATAGAAGCTAAAGAAGGCGTTAGAGTAGAAAG AGAATCTAAAACTTTAGCTACAATAACTTATCAAAACTATTTTAGAATGTACAATAAATTGTCTGGTATGACAGGAACTG CTCAAACAGAAGAAAATGAATTTAGAGAAATCTATGGATTAGATGTAATTGTAATACCTACACATGAGCCTATAGCAAGA ATAGATAATGCTGATGTAGTATATAAATCAGAAAAGGGTAAATTTAAAGCCATAGTTGATGAAATAGTAGAAAGATATAA AAAAGGTCAACCAATGCTAGTAGGTACAGTAAGCATAGAAAAATCAGAAATGTTATCCTCTATGTTAAAGAAAAAAGGAG TACCTCATCAAGTATTAAATGCTAAATATCATGAAAAAGAAGCGGAAATAATATCTCATGCAGGGGAATATGGGATGGTT ACAATAGCCACTAATATGGCAGGCCGTGGTACAGATATAAAGCTTACTAAGGAAGCTGAAGAAGCAGGCGGGCTTATGAT TATAGGTACAGAAAGACATGAGTCTAGAAGAATAGACAACCAATTAAGAGGACGTTCTGGTCGTCAAGGAGATCCTGGTG AATCAAGATTTTTTGTATCTTTAGAAGATGATTTAATGAGAATATTTGGTTCAGAAAGAATACAAGGAATAGTTGATAAA TTAGGACTCGCTGAAGATGAAGCTATAGAAAGTAAAATGGTAAGTTCAGCTATAGAAAGTGCTCAAAAGAAGGTAGAAGG AAATAACTTTGATATAAGAAAAACTTTATTACAATATGATGATGTAATAAATAAACAAAGAGAAATAATCTATAAACAAA GAAGTGAGGTTTTAGAGGGAGAAGACTTAAAGGATCAAATAAGAGATATGATAAGGGATGTGGTTTATACTGCAGTAAAT TCTCATATTTCAGGAGTAGAAGAAGAGTTTGAAACAGAACTTCAAAATCTTGTTAATTATTTAGAAGACATATGCTTACC AAAGGCCTTAGTAAAGGTAAAAGATATAAGTAATTTATCAGATGAAGAAATAAAAGAAAAATTATTAGAAGCAGTAGAAA ATATATATAGCCGCAAAGAAAAAGAAATTGGGGAAGAACAAATAAGAGAAATAGAAAGAGTAATATTGCTTAGGGTTGTA GATACTAAATGGATGGATCATATAGATGATATGGATCACTTAAAACAAGGTATAGGACTAAGAGCATATAGACAACAAGA TCCAGTTCAAGCATATCAATTTGAAGGTAGTGAAATGTTTGAGGAAATGATCTATAACATTAAAGTAGATACAGTAAGAT ATTTATTCCATGTAGAAGTAGAAAAAGCACCTGAAAGAGAGAAAGTGGCAAAAGAAACATCAACTAATTATGATGAAGAT TCAGTAAAAAAACAACCTATAAAAAAAGAAAATAGAATAGGTAGAAATGATATGTGTCCTTGCGGAAGTGGAAAAAAATA TAAAAATTGTTGTGGTAGAATGGCATAA Protein sequence : MGILNKIFGTYSERELRRVNPIVNKIEALDEKMQSLKDEDFKLKTEEFKSRLEKGEKLDDILPEAFALVREAAHRTIGLK HYREQLIGGVVLHQGRIGEMKTGEGKTLVATLPAYVNALTGKGVHIVTVNDYLAKRDRDLMAPVYEFLGLKVGVILHNLN NEERQEAYGSDITYGTNSEFGFDYLRDNMVVYKEERVQRKLNFSIVDEVDSILIDEARTPLIISGQGEKSTEFYKVADYF TKSLIAEKDFTIDEKANSAMLTDEGVNKAENFFKVDNYADAENMEIQHHVVQALKANYVMKKDKDYMIKDGEILIVDEFT GRAMEGRRYSDGLHQAIEAKEGVRVERESKTLATITYQNYFRMYNKLSGMTGTAQTEENEFREIYGLDVIVIPTHEPIAR IDNADVVYKSEKGKFKAIVDEIVERYKKGQPMLVGTVSIEKSEMLSSMLKKKGVPHQVLNAKYHEKEAEIISHAGEYGMV TIATNMAGRGTDIKLTKEAEEAGGLMIIGTERHESRRIDNQLRGRSGRQGDPGESRFFVSLEDDLMRIFGSERIQGIVDK LGLAEDEAIESKMVSSAIESAQKKVEGNNFDIRKTLLQYDDVINKQREIIYKQRSEVLEGEDLKDQIRDMIRDVVYTAVN SHISGVEEEFETELQNLVNYLEDICLPKALVKVKDISNLSDEEIKEKLLEAVENIYSRKEKEIGEEQIREIERVILLRVV DTKWMDHIDDMDHLKQGIGLRAYRQQDPVQAYQFEGSEMFEEMIYNIKVDTVRYLFHVEVEKAPEREKVAKETSTNYDED SVKKQPIKKENRIGRNDMCPCGSGKKYKNCCGRMA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| secA2 | YP_006310687.1 | preprotein translocase subunit SecA2 | Not tested | FWisland_3 | Protein | 3e-121 | 41 |
