Gene Information

Name : serS (CLM_0022)
Accession : YP_002802328.1
Strain : Clostridium botulinum Kyoto
Genome accession: NC_012563
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 22539 - 23819 bp
Length : 1281 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAGATTTAAAAAGAATAAGAAATAATTCAAATGAAATAAAAGAAGCATTAAACAATAGAGGAGAAAAGTTTGATGT
AACTGTAATTGATGAAGTTTTAAAATTAGATGAAGAAAGAAGAAATATTTTAGTTAAAGTTGAGGTTTTAAAAAGTAAGA
GAAATAAAGTTTCTTCTGAAGTTCCTAAATTAAAAAAAGAAGGAAAAGATGTATCTAATATAGTAGCTGAAATGAAGAAT
TTATCAGAAGAGATAAAAGGATTTGATGTTACTTTAGCTAAAATAGATGAAAAAATACAATATATAATGCTTAGAATACC
TAATATACCCAACCCACAAGTTCCAGATGGAGAAACAGATGAGGATAATATAGAAATAAGAAATTGGCTGGAACCAACAA
AATTTGATTTTGAACCTAAAGCACATTGGGATATAGGAACAAATTTAAATATTCTTGATTTTGAAAGAGCTGGAAAAGTA
ACAGGATCAAGATTTACTTTTTATAAAGGATTAGGGGCTAGATTAGAAAGAGCAGTAATATCTTATTTTTTAGATACTCA
TACAGAAAAACATGATTATACTGAAATATTACCACCTTATATGGTAAATAGAACAAGTATGATAGGAACAGGACAATTAC
CTAAATTTGAAGAAGACGCTTTTAAAATCTCAGAGGATGATTACTTCTTAATACCAACTGCAGAGGTTCCTGTAACTAAT
TTATATAGAGATGAAATCTTAAAAGGTGATGAATTACCATTAAAACATGTAGCTTATAGTGCTTGTTTTAGATCAGAAGC
AGGTTCAGCAGGTAGAGATACAAGAGGTCTTGTTAGACAACATCAATTTAATAAAGTAGAGCTTGTTAAATTTACAAAAC
CAGAACAATCCTATGAAGAATTGGAAAAATTAACTAATGATGCTGAAACAGTATTAAAAGAGTTGGGTATTCCATATAGA
GTTGTAAGAATATGCAAAGGTGATTTAGGATTTACAGCTGCATTAAAATATGATTTAGAAGTTTGGATGCCAAGTTACAA
TAGATATGTTGAAATATCAAGCTGTAGTAACTTTGAAGACTTCCAAGCAAGACGTGCTAATATAAGATATAAAGAAGATG
CAAAAGCAAAACCACAATATGTTCATACATTAAATGGATCAGGAGTTGCTATTGGAAGAACTGTTGCAGCTATACTTGAA
AACTATCAAAGTGAAGATGGATCAGTTACAATACCAGAAGTGTTAAGACCTTATATGGGAGGAAGAGAAGTAATAAAATA
A

Protein sequence :
MLDLKRIRNNSNEIKEALNNRGEKFDVTVIDEVLKLDEERRNILVKVEVLKSKRNKVSSEVPKLKKEGKDVSNIVAEMKN
LSEEIKGFDVTLAKIDEKIQYIMLRIPNIPNPQVPDGETDEDNIEIRNWLEPTKFDFEPKAHWDIGTNLNILDFERAGKV
TGSRFTFYKGLGARLERAVISYFLDTHTEKHDYTEILPPYMVNRTSMIGTGQLPKFEEDAFKISEDDYFLIPTAEVPVTN
LYRDEILKGDELPLKHVAYSACFRSEAGSAGRDTRGLVRQHQFNKVELVKFTKPEQSYEELEKLTNDAETVLKELGIPYR
VVRICKGDLGFTAALKYDLEVWMPSYNRYVEISSCSNFEDFQARRANIRYKEDAKAKPQYVHTLNGSGVAIGRTVAAILE
NYQSEDGSVTIPEVLRPYMGGREVIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 5e-128 61