Gene Information

Name : hemC (CLM_1068)
Accession : YP_002803284.1
Strain : Clostridium botulinum Kyoto
Genome accession: NC_012563
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 1117795 - 1118667 bp
Length : 873 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
TTGAATTTTGTAATAGCCACACGAAGAAGTAAGCTTGCTCAGGTGCAAACAGAAATAATAATAGATTTATTAAATAAAAA
GCATGATATAGAATGTGAAAAATTATTAATAGAAACCGTAGGAGATAAAATATTAGAAGTATCTTTAGATAAGATAGGTG
GAAAAGGGCTATTTGTTAAAGACATAGAAGTAGCTATGTTAGAACAAAGGGCAGATGCAGCAGTACATAGTATGAAGGAT
GTGCCCTATGAAATGCCAAAAGGTTTTGAGATAATAGCTATTCCAGAGCGAGAAGATGTAAGAGATGCCTTTATATCCTT
AGACAATATAAAATTTAAGGATTTAAGAAAGGGAGCTAAAATTGGTACAAGTAGTAGGAGAAGGGCAGCCCAATTAAAAC
TTCTAAGGCCAGATTTAGATATTGTACCCATAAGAGGAAATGTTCAAACTAGAATAGAAAAAATAAAAAAAGAAAATCTA
GATGGAATAATATTAGCAGTAGCAGGCCTTAAAAGGGTAAATTTAGATCATTTAATTACAGACTATTTTGATACAAAAGA
AATGGTACCCGCAATTGGTCAAGGTGCCTTAGGTATAGAAGTTATGGAGGAGCATCCTAAAAAGGAGTTATTTAAGGATT
TAGATCATTATAATTCAAAAATATGTGTTTTGGCAGAAAGAGCTTTTATGAGGGAACTAGATGGAGATTGCCACTCAACT
ATAGGAGCTTATGCATCTATAAAGGATAATATAATGCATATAATAGGCATATTTGAAAGAAAAAATAAAATTATTAAAAA
AGAAATCACAGGAACAAAAGATCAGTATGAAAAATTAGGCATATCTCTAGCAGAACATATACTAAAAGACTAA

Protein sequence :
MNFVIATRRSKLAQVQTEIIIDLLNKKHDIECEKLLIETVGDKILEVSLDKIGGKGLFVKDIEVAMLEQRADAAVHSMKD
VPYEMPKGFEIIAIPEREDVRDAFISLDNIKFKDLRKGAKIGTSSRRRAAQLKLLRPDLDIVPIRGNVQTRIEKIKKENL
DGIILAVAGLKRVNLDHLITDYFDTKEMVPAIGQGALGIEVMEEHPKKELFKDLDHYNSKICVLAERAFMRELDGDCHST
IGAYASIKDNIMHIIGIFERKNKIIKKEITGTKDQYEKLGISLAEHILKD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 3e-48 43
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 3e-48 43