Gene Information

Name : thyA (Avin_48170)
Accession : YP_002801896.1
Strain : Azotobacter vinelandii DJ
Genome accession: NC_012560
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : -
Position : 4882933 - 4883727 bp
Length : 795 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAACAGTACCTCGACCTGATGCGCCTGGTGCGCGAGCACGGCACCTTCAAGAGCGACCGCACCGGCACCGGCACGTT
TTCCGTGTTCGGCCACCAGATGCGCTTCGACCTGGCCGAGGGCTTCCCGCTGGTCACCACCAAGAAGTGCCACCTCAAAT
CCATCGTCCACGAGCTGCTGTGGTTCCTGAAGGGCGACACCAACATCCGCTACCTGAAGGAAAACGGCGTGTCGATCTGG
GACGAGTGGGCCGACGGGAACGGCGACCTCGGCCCGGTCTACGGCTACCAGTGGCGCAGTTGGCCGGCACCGGACGGCCG
GCACATCGACCAGATAGCCAATGTCGTGAACATGATCCGCGACAACCCGGATTCGCGCCGGCTGATCGTCTCGGCCTGGA
ACCCGGCGCTGATCGACGAGATGAAGCTGCCGCCGTGCCATGCGCTGTTCCAGTTCTACGTGGCCGATGGCCGGCTCAGC
TGCCAGCTCTATCAGCGCTCGGCGGACATCTTCCTCGGCGTGCCCTTCAACATCGCCAGCTACGCGCTGCTGATCCTGAT
GATGGCGCAGGTCACGGGCCTCGCGCCCGGCGAGTTCGTCTGGACCGGCGGCGACTGCCACCTCTACGCCAACCACTTGG
AGCAGGCCGACCTGCAGCTCTCCCGCGAACCGCTGCCGCTGCCGACCATGCAGCTCGACCCCGACGTGAAGGACCTGTTC
GCCTTCCGCTTCGAGGACTTCGAGCTGGTCGGCTACCAGTCCCATCCGCACATCAAGGCGCCGGTGGCGATCTGA

Protein sequence :
MKQYLDLMRLVREHGTFKSDRTGTGTFSVFGHQMRFDLAEGFPLVTTKKCHLKSIVHELLWFLKGDTNIRYLKENGVSIW
DEWADGNGDLGPVYGYQWRSWPAPDGRHIDQIANVVNMIRDNPDSRRLIVSAWNPALIDEMKLPPCHALFQFYVADGRLS
CQLYQRSADIFLGVPFNIASYALLILMMAQVTGLAPGEFVWTGGDCHLYANHLEQADLQLSREPLPLPTMQLDPDVKDLF
AFRFEDFELVGYQSHPHIKAPVAI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 8e-86 66