Gene Information

Name : kdsB (Avin_14780)
Accession : YP_002798669.1
Strain : Azotobacter vinelandii DJ
Genome accession: NC_012560
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : -
Position : 1459391 - 1460155 bp
Length : 765 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGAGCAAAGCCTTCTGCGTGGTGATTCCCGCCCGCTACGCCTCGAGTCGCCTGCCGGGCAAGCCGCTGCAGGACATCGC
CGGCAAGCCGATGATCCAACATGTCTGGGAGCAGGCCCGGCGCAGTGGGGCGCAGCGGGTGGTGGTGGCCACTGACGATG
CGCGCATCGAGGCGGCCTGCCAGTCCTTCGGGGCCGAGGCGTTGCTGACCCGTGTCGAGCACAACTCCGGGACCGATCGG
CTGGCCGAAGTGGCTGGACGGCTCAGCCTGGCCGACGACGCCGTAGTGGTCAACGTGCAGGGCGACGAGCCGTTGATCCC
TCCCGCGCTCATCGACCAGGTGGCGGAAAACCTGGCGGCCCATCCGGAGGCGGCCATCGCTACCCTGGCCGAGCCGATCG
ACAGCGCCGAGGCCCTGTTCAATCCGAATGTGGTGAAGGTCGCGAGCGATATCCACGGCCTGGCCCTGACCTTCAGCCGC
GCTCCCTTGCCCTGGGCGAGGGATGCCTTCGCCGGCAGCCGCGAATGCTTGCCGGCGGGTGTGCCTTATCGCCGGCACAT
CGGCATCTACGCCTATCGGGCGGGCTTTCTCCGCGATTTCGTCGCCTGGGGGCCGTGCTGGCTGGAAAGCGTCGAAAGCC
TGGAGCAGTTGCGTGCGCTCTGGCATGGTGCGCGCATCCATGTGGCTGATGCCCTGGAGGCGCCGCAGGCCGGTGTGGAT
ACCCAGGAAGACCTCGAGCGCGTACGGCGCCTGTTGGGGGCCTGA

Protein sequence :
MSKAFCVVIPARYASSRLPGKPLQDIAGKPMIQHVWEQARRSGAQRVVVATDDARIEAACQSFGAEALLTRVEHNSGTDR
LAEVAGRLSLADDAVVVNVQGDEPLIPPALIDQVAENLAAHPEAAIATLAEPIDSAEALFNPNVVKVASDIHGLALTFSR
APLPWARDAFAGSRECLPAGVPYRRHIGIYAYRAGFLRDFVAWGPCWLESVESLEQLRALWHGARIHVADALEAPQAGVD
TQEDLERVRRLLGA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 5e-41 45
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 1e-40 45
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 4e-41 45