Gene Information

Name : metB (LHK_00716)
Accession : YP_002794718.1
Strain : Laribacter hongkongensis HLHK9
Genome accession: NC_012559
Putative virulence/resistance : Resistance
Product : MetB
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 691671 - 692816 bp
Length : 1146 bp
Strand : +
Note : Cystathionine gamma-synthase

DNA sequence :
ATGAAGTTTGCCACTCGCGCCATCCATGCCGGCTATGAACGTGACCCGGCCACGCATGCGGTCATGCCTCCGGTGTACCA
GACCTCGATTTTCAGCTACGACCGGCTGGGCGACGAGCAGCCGTACTCCTATTCACGTTCGGCCAATCCGACCCGTGCAG
CGCTGGAGGCCAATGTGGCGGCGCTGGAAGGCATGCAGTACGGCCTGGCTTTCGGCAGCGGCATGGCCGCCATTGATGCC
GTGCTGCGCGCCACGCTGGTCGCCGGCGACGAAGTGATCGCACTGGCCGACTGTTACGGTGGTGCCTACCGGCTGCTGAC
CCGGATCTATGCCCCGGCCGGCGTGACGGTGACGTTCCTGGACCTGACCACCCGCCCGGAGCTGCTGGAAGACGCCATTG
GCGAACGCACCCGGCTGGTCTGGCTGGAATCCCCCACCAATCCGCTGCTCAAGCTGGTGGACCTGCCGCGCGTGGCCGCC
ATCTGCCGCGCCCGTGGCGTGACCACCGCCATCGACAACACGTTTGCCTCGCCGTACCTGCAAAACCCGCGCGATTCCGG
CATCGACATCGTCATGCACTCGGCCACCAAATACCTGGCCGGCCACTCGGACGTGATCCTCGGCGTGGTCTGTACCGACA
ACGAGCAGCTGGCCGCCAGGCTCAAGCTGGTACAGAACTCGGCCGGTGCCGTGCCGGGACCGCAGGACTGCTTCCTGGCC
CTGCGCGGCATCAAGACCCTGGCCTTGCGCATGCAGCGCCACTGCGACAATGCCATGGCCGTGGCCGGTTTCCTGGCCAC
GCATCCGGCGATCGACAAGGTGATTTATCCCGGACTGCCGACGCACCCTCAGCATGAGCTGGCCAGCCGGCAGATGCGCG
GCTTTGGCGGCGTGGTCACCATCTATTTGAAGGATGACTCGCGGGCAGCCGCCGCACAGGTGGCCGAGCGGCTGCAATGG
TTTGCGCTGGGCGAGTCGCTCGGCGGGGTGGAAAGCATCGTCAACCATTCCGCCACCATGTCGCATGGCTCGATGCCGGC
CGGGGTGAAACAGGCGCTCGGCATTCGTGAAGGCATGCTGCGGCTGTCGGTCGGTATCGAGGACGTGGACGACCTGCTGG
CCGACCTTGCGCAGGCGCTGGCGTAA

Protein sequence :
MKFATRAIHAGYERDPATHAVMPPVYQTSIFSYDRLGDEQPYSYSRSANPTRAALEANVAALEGMQYGLAFGSGMAAIDA
VLRATLVAGDEVIALADCYGGAYRLLTRIYAPAGVTVTFLDLTTRPELLEDAIGERTRLVWLESPTNPLLKLVDLPRVAA
ICRARGVTTAIDNTFASPYLQNPRDSGIDIVMHSATKYLAGHSDVILGVVCTDNEQLAARLKLVQNSAGAVPGPQDCFLA
LRGIKTLALRMQRHCDNAMAVAGFLATHPAIDKVIYPGLPTHPQHELASRQMRGFGGVVTIYLKDDSRAAAAQVAERLQW
FALGESLGGVESIVNHSATMSHGSMPAGVKQALGIREGMLRLSVGIEDVDDLLADLAQALA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 9e-72 44
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 8e-73 44
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 3e-53 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB YP_002794718.1 MetB BAC0207 Protein 2e-62 42