Gene Information

Name : hemC (LHK_03136)
Accession : YP_002797123.1
Strain : Laribacter hongkongensis HLHK9
Genome accession: NC_012559
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 3049525 - 3050451 bp
Length : 927 bp
Strand : -
Note : Porphobilinogen deaminase; transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGAAGCAAGTCGTCATTGCCAGCCGCGAGAGCCCGCTTGCCATGTGGCAGGCCGAGCATATCCGGGCGCGTTTGCAGGC
GCTGTATCCGGGGCTGGAGGTCAGCATCCTGGGCATCACCACGCAGGGCGACCGCATTCTGGACAAAACCCTGAACAAGA
TCGGCGGCAAAGGGCTATTCGTCAAGGAGCTTGAGCTAGCCATGCAGGAAGGCCAGGCCGACCTGGCGGTGCACTCGATC
AAGGACGTGCCGATGGATCTGCCCGAAGGCTTTGCGCTGGCGGCGATCTGCGAACGCGAGGACCCGCGCGATGCCTTCGT
GTCGTCGCGCTACGCCAGCCTCTCGGAGCTGCCGGCCGGCGCCGTGGTCGGCACGGCCAGCCTGCGCCGCGAAAGCCAGA
TCCGCGCCCGCTATCCGCACCTCCTGGTGAAGCCGCTGCGCGGCAACCTGCAAACGCGGCTGCGCAAGCTCGACGAAGGC
CAGTACGACGCCATCATCCTGGCGGCCTCCGGCCTCAAGCGCATGGGGCTGGCCGAGCGCATCCGCATGGAGCTGTCGAC
TGCCGACAGCCTGCCGGCCGTGGGGCAGGGCGCGCTGGGCATCGAAATCCGTGCCGACCGCACCGACCTGATGGCGCTCC
TGGCGCCGCTCAACCATCCGGCCACCTACGCCTGCGTCACGGCCGAGCGCGCCATGGGCCGGGCGCTGGGTGCGAGCTGC
CAGATTCCGGTGGGCGGCTATGCCGAGCAGCACGAGCACATGCTGGTCATGCGTGGCTTTGTGGCCACACCCGACGGCAC
CACCCTGCTGCACGCCGAAGCCACGGCTCCGGCCGAATACGCCGACGCGCTGGGCCGCACGATTGCGAAGAAACTGCTGG
ACCAGGGCGCCGACGACGTGATCGACGCGGTGAAGGCTGCCGGCTGA

Protein sequence :
MKQVVIASRESPLAMWQAEHIRARLQALYPGLEVSILGITTQGDRILDKTLNKIGGKGLFVKELELAMQEGQADLAVHSI
KDVPMDLPEGFALAAICEREDPRDAFVSSRYASLSELPAGAVVGTASLRRESQIRARYPHLLVKPLRGNLQTRLRKLDEG
QYDAIILAASGLKRMGLAERIRMELSTADSLPAVGQGALGIEIRADRTDLMALLAPLNHPATYACVTAERAMGRALGASC
QIPVGGYAEQHEHMLVMRGFVATPDGTTLLHAEATAPAEYADALGRTIAKKLLDQGADDVIDAVKAAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 1e-79 60
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 1e-79 60