Gene Information

Name : lysS (LHK_02425)
Accession : YP_002796416.1
Strain : Laribacter hongkongensis HLHK9
Genome accession: NC_012559
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 2316555 - 2318066 bp
Length : 1512 bp
Strand : +
Note : Lysyl-tRNA synthetase; class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, L

DNA sequence :
ATGTCCGAACAAGACATCACGAGCCAGCCCGCGCAGGATGAAAACCAGATCATGGCCGAGCGTCGCCAGAAGCTCACCGA
GATCCGGACCAGCAAAGGCATCGCCTTCCCCAACGATTTCCGCCGCCAGCACTTGGCTGCCCCGCTGCACGCACAGTACG
ATGCCACCGACAAGGAAGCGCTCGAAGCCCAGCCGGTCGAAGTCGTCGTCGCCGGCCGCATGATGCTCAAGCGTGTGATG
GGCAAGGCCAGCTTTGCCACGGTGCAGGACAGCTCGGGCCGCATCCAGTTCTACATCAGCCGCGACAAGGTGGGTGAAGA
TGTCTACGCGGACTTCAAGACCTGGGACATGGGTGACATTCTCGGCGCCAAAGGCACCCTGATGAAGACCAAGACCGGCG
AACTGTCGGTCGAAGTGAGCGAGCTGCGCCTGCTCTCCAAGTCGCTGCGCCCGCTGCCTGACAAATTCCACGGTCTGGCT
GACCAGGAACAGAAATACCGCCAGCGTTACGTTGACCTGATCATCAACCAGGACAGCCGTGACACCTTCATCAAGCGCTC
GAAAATCGTACAGACCGTACGCGAAGTCATGGTGGGCGAAGACTACCTCGAAGTCGAAACCCCGATGATGCACCCGATCC
CGGGTGGCGCTGCTGCCAAACCGTTCGTCACCCACCACAATGCCCTCGACATGCCGCTCTACCTGCGCATCGCACCGGAG
CTGTACCTCAAGCGGCTGGTCGTGGGCGGACTGGAGCGCGTGTTCGAAATCAACCGCAACTTCCGCAACGAGGGGATGAG
CACCCGCCACAACCCCGAGTTCACCATGATCGAGTTTTACGAGGCCTACTGCGGCTACGAGCGCATGATGGAGATGACCG
AAAAGATCATCCGTCGCTGCGCTGAAGCAGCCTGCGGCACCACCAAGGTGACCTACAACGGCAAGGAAGTCGATCTGGGC
AAGCCGTTTGATCGCTTTACCATCGTCGGTGCCATCAAGCACTACAACCCGCAATACACCGACGAACAGCTGGCCGACGA
AGCCTGGCTCAAGAGCGAAATCAAGGCGCTGGGCGGCAAGCTGCCCCCGGCTCCGGGCATCGGCAGCCTGCAACTGGCCC
TCTTTGAAGAATGCGCCGAAGGCAAGCTGTGGAATCCGACCTTCATCATCGACTACCCGGTTGAAGTCTCGCCGCTGGCA
CGCGGCTCGGATGCCGATCCGTCAATCACCGAGCGCTTCGAGCTCTTCATCGTCGGCCGCGAACATGCCAACGGCTATTC
GGAGCTTAACGATCCGGAAGACCAGGCTGCCCGCTTCCGCTCGCAAGTCGAGCAAAAGGATGCCGGCGACGATGAGGCCA
TGCACTACGACGCCGACTATATCCGTGCCATGGAATACGGTCTGCCCCCGACCGGCGGCTGCGGCATCGGTATTGACCGT
CTGGTCATGCTGCTGACCGATGCCCCGTCGATCCGCGATGTCATCCTGTTCCCGCACATGAGGCCTGAATAA

Protein sequence :
MSEQDITSQPAQDENQIMAERRQKLTEIRTSKGIAFPNDFRRQHLAAPLHAQYDATDKEALEAQPVEVVVAGRMMLKRVM
GKASFATVQDSSGRIQFYISRDKVGEDVYADFKTWDMGDILGAKGTLMKTKTGELSVEVSELRLLSKSLRPLPDKFHGLA
DQEQKYRQRYVDLIINQDSRDTFIKRSKIVQTVREVMVGEDYLEVETPMMHPIPGGAAAKPFVTHHNALDMPLYLRIAPE
LYLKRLVVGGLERVFEINRNFRNEGMSTRHNPEFTMIEFYEAYCGYERMMEMTEKIIRRCAEAACGTTKVTYNGKEVDLG
KPFDRFTIVGAIKHYNPQYTDEQLADEAWLKSEIKALGGKLPPAPGIGSLQLALFEECAEGKLWNPTFIIDYPVEVSPLA
RGSDADPSITERFELFIVGREHANGYSELNDPEDQAARFRSQVEQKDAGDDEAMHYDADYIRAMEYGLPPTGGCGIGIDR
LVMLLTDAPSIRDVILFPHMRPE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 2e-122 54
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 2e-76 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_002796416.1 lysyl-tRNA synthetase VFG1668 Protein 1e-122 54