Gene Information

Name : leuS (LHK_00119)
Accession : YP_002794124.1
Strain : Laribacter hongkongensis HLHK9
Genome accession: NC_012559
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 118615 - 121215 bp
Length : 2601 bp
Strand : -
Note : Leucyl-tRNA synthetase; leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu

DNA sequence :
ATGCACGAACAGTACCAGCCCCGCGACATTGAGGTCGCCGCCCAGCAGAAATGGGAAAAGACCGCCGCCTTCAAGGCCGT
GGAAGATGCCAGCCGCCCGAAATACTACTGCCTGTCGATGTTCCCCTACCCGTCGGGCAAGCTGCACATGGGCCATGTGC
GCAACTACACCATCGGCGACGTGCTGTCGCGCTACATGGCGCTCAAGGGCTACAACGTGTTGCAACCGATGGGCTGGGAC
GCCTTCGGCATGCCGGCGGAAAACGCCGCCCTCAAGAACCAGGTCGCACCGGCTGCCTGGACCTACTCGAACATCGAGTA
CATGAAGACCCAGCTCAAGAGCCTTGGCTTTGCCATCGACTGGGAGCGCGAAGTCACCACCTGCAAGCCGGACTACTACC
GCTGGGAGCAGTGGCTGTTCACCCGCCTGTTTGAAAAGGGCGTGATCTACCGCAAGAACGGCGTGGTGAACTGGGACCCG
GTCGACCAGACCGTACTCGCCAACGAACAGGTGATCGACGGCCGCGGCTGGCGCTCCGGGGCGCTGGTGGAAAAGCGCGA
AATCCCGATGTACTACTTCGGCATCACCCAGTACGCTGACGAACTCTTGGCCGACCTCGACACCCTCGACTGGCCGCCGC
AGGTCGCCACCATGCAGCGCAACTGGATCGGCAAGAGCTTCGGCGCCGACGTACGCTTTGCCTACGACGAAGCCAGCATC
GGCAGCGCCGGCGAGCTGACCGTCTACACCACCCGGCCGGATACCCTGATGGGTGCCACCTACGTGGCTGTCGCCGCCGA
ACACCCGCTGGCCACCCAGGCTGCCGCGAACGATCCGGCACTCCAGGCCTTCATCGCCAAATGCAAGGCCGGCTCGGTCG
CCGAAGCCGACATGGCGACCATGGAAAAGGAAGGCATGCCGACCGGTCTCTTCGTCGTGCATCCGCTCACCGGCGCAAAA
CTGCCGGTCTGGGTCGCCAACTACGTGCTGATGAGCTACGGCTCCGGTGCGGTGATGGCGGTACCGGCGCACGACGAGCG
CGACTTTGCCTTCGCCAACAAGTACGCCCTGCCGATCCAGCAGGTCATCGCCCTCAAGGAGGGCGACGCCACGTTCGACG
CCAGCACTTGGCAGGACTGGTACGCCACCAAGGACGACAGCACCCGCCTCGTCAACTCGGGCAAGTACGACGGCCTCGAC
TTCCAGGGCGCCTTTGACGCCATCGTCGCCGACCTCGCCGCCAAGGCCGCCGGGGAAAAGAAAACCCAGTACCGCCTGCG
CGACTGGGGCATCAGCCGCCAGCGTTACTGGGGCTGCCCGATCCCGATCATCCACTGCGACAGCTGCGGTGACGTGCCGG
TCCCGGCCGACCAGCTGCCAGTGGTGCTGCCGGAAAACGTGGTGCCGGATGGCAGCGGCAACCCGCTGGCCAAGATGCCC
GAATTCTACGAAACCACCTGCCCGTGCTGCGGCAAGCCGGCGCGGCGCGAAACCGACACCATGGATACCTTCGTGGAGTC
GAGCTGGTACTTTGCCCGCTACGCCTCGCCCGACTGCGCCACCGGCATGGTCGACGACCGCGCCCGCTACTGGCTCAACG
TCGACCAGTACATCGGCGGCATCGAACACGCCATCCTGCACCTCCTGTACGCGCGCTTCTTCAACAAGCTGATGCGCGAC
GAAGGCCTGCTCGCCAACGACGAACCGTTCCAGAGGCTGCTGACCCAGGGCATGGTGGTATGCGAAACCTTCTACCGTGA
CCTCGACAACGGCAGCAAGGAATGGATCACCCCGGCCGACGTGGTCATCGAACGCGACGGAAAGGGCAAGATCATTGCCG
CCACCCACAAGGCCGACGGCCTGCCGGTCGTGGTCGGCGGCATCGAGAAGATGTCGAAGTCGAAGAACAACGGCGTCGAC
CCGCAGGCACTGATCGAACAGTACGGCGCCGACACCGCGCGTCTCTTCATGATGTTTGCCGCACCGCCGAGCCAGTCGCT
CGAATGGTCGGACGCCGGCGTGGAAGGGGCGTACCGCTTCCTCAAGCGCCTCTACAAGATCGTGAGCGAATACGTCGCTG
GCGGTGTAGCCGAACGCTTCGTGGCCGGCGAGCTGACCGCCGACGAAAAGGCCCTGCGCCTGAAGCTGCACACCACCATC
CAGAAGGTCAGCGACGACTTCGGCGTACGCCAGCAGTTCAACACCGCCATCGCCGCCGTGATGGAACTTCTCAACCTCTT
TGACCGCACCGAAGCCTCGCGCGCCGTCAGGCAGGAAGTACTGGAAAGCGTGGTGGTCCTGCTGTCGCCGATCGTGCCGC
ACATCTGCGAAACCCTGTGGAGCGCGCTCAAGCCCGGCAGCGAACTACTGGCCCAGCGCTGGCCGGAAGTCGATCCGGCG
GCCCTGGTGCAGGACGAAATCGAGCTGGTGGTGCAGGTCAACGGCAAGCTGCGCGGTTCGGTCCGCGTGGCCGCTGACGC
CGGCCGCGACGTGATCGAGGCCGCCGCCCTGGCGCACGAACAGGTCCGCAAGTTCATGGACGGCCAGCCGGCCAAAAAAG
TGATCGTGGTCCCGGGCCGCCTCGTCAACATCGTGGTCTGA

Protein sequence :
MHEQYQPRDIEVAAQQKWEKTAAFKAVEDASRPKYYCLSMFPYPSGKLHMGHVRNYTIGDVLSRYMALKGYNVLQPMGWD
AFGMPAENAALKNQVAPAAWTYSNIEYMKTQLKSLGFAIDWEREVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGVVNWDP
VDQTVLANEQVIDGRGWRSGALVEKREIPMYYFGITQYADELLADLDTLDWPPQVATMQRNWIGKSFGADVRFAYDEASI
GSAGELTVYTTRPDTLMGATYVAVAAEHPLATQAAANDPALQAFIAKCKAGSVAEADMATMEKEGMPTGLFVVHPLTGAK
LPVWVANYVLMSYGSGAVMAVPAHDERDFAFANKYALPIQQVIALKEGDATFDASTWQDWYATKDDSTRLVNSGKYDGLD
FQGAFDAIVADLAAKAAGEKKTQYRLRDWGISRQRYWGCPIPIIHCDSCGDVPVPADQLPVVLPENVVPDGSGNPLAKMP
EFYETTCPCCGKPARRETDTMDTFVESSWYFARYASPDCATGMVDDRARYWLNVDQYIGGIEHAILHLLYARFFNKLMRD
EGLLANDEPFQRLLTQGMVVCETFYRDLDNGSKEWITPADVVIERDGKGKIIAATHKADGLPVVVGGIEKMSKSKNNGVD
PQALIEQYGADTARLFMMFAAPPSQSLEWSDAGVEGAYRFLKRLYKIVSEYVAGGVAERFVAGELTADEKALRLKLHTTI
QKVSDDFGVRQQFNTAIAAVMELLNLFDRTEASRAVRQEVLESVVVLLSPIVPHICETLWSALKPGSELLAQRWPEVDPA
ALVQDEIELVVQVNGKLRGSVRVAADAGRDVIEAAALAHEQVRKFMDGQPAKKVIVVPGRLVNIVV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 5e-139 41