Gene Information

Name : kdsB (LHK_01104)
Accession : YP_002795105.1
Strain : Laribacter hongkongensis HLHK9
Genome accession: NC_012559
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 1070558 - 1071322 bp
Length : 765 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence : 
ATGGCTGGCGGTTTTGTCGTCGTCATCCCGGCGCGCCTCAAGTCCACGCGTCTGCCTGACAAGCCGCTGGCCGACATTGC
CGGCAAGCCGATGGTGGTGCGCGTGGCCGAGCGGGCCTTGCAGTGCGGCGCATCCCGCGTGGTGGTGGCGACCGATCATG
CCAGCATCGTCGATGCATGTGCCGCTCATGGTGTCGAGGCCCTGCTGACGCGCGCGGATCATCCGAGCGGCACCGACCGT
CTGGCCGAAGTGGCTGACCTGCTGGCTCTGCCGGATGACCAGGTGGTCGTGAACGTGCAGGGCGACGAGCCGTTGATCGA
GCCGGCCGTCATTGACCGGCTGGCAGCCACGCTGGCCGGCAGTAGTGCCCCGATGGCCACGGTGGCCCATCCGGTGCACG
ATGCCGACGATTTTTTTAACCCCAATGTTGTCAAGGTCGTTCTTGACCGGCATGGCGAGGCTCTTTACTTTAGCCGGGCC
CCGCTGCCTTGGGCCCGCGATGCGTTCGCTGCCCGGCCGGACGTACTGCCGCCAGACATGGCGGCATTGCGTCACGTCGG
ATTGTACGCCTATCGCGCTGCATTCCTGCGGCAATACCGCTCGCTGGAAGCTTCCCCGCTGGAATCCTTGGAGGCGCTTG
AGCAATTGCGCGTGCTCTGGCACGGATTCCGGATCGCGGTCACCGTGCTTGACGCTACACCGGCTGCTGGCGTGGATACG
CCCGCAGACCTTGAGCGCGTGCGCCAGAGTTTTGCAGCACCCTGA

Protein sequence : 
MAGGFVVVIPARLKSTRLPDKPLADIAGKPMVVRVAERALQCGASRVVVATDHASIVDACAAHGVEALLTRADHPSGTDR
LAEVADLLALPDDQVVVNVQGDEPLIEPAVIDRLAATLAGSSAPMATVAHPVHDADDFFNPNVVKVVLDRHGEALYFSRA
PLPWARDAFAARPDVLPPDMAALRHVGLYAYRAAFLRQYRSLEASPLESLEALEQLRVLWHGFRIAVTVLDATPAAGVDT
PADLERVRQSFAAP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 8e-34 47
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 6e-34 47
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 1e-33 46