Gene Information

Name : tkt (ROP_69670)
Accession : YP_002784159.1
Strain : Rhodococcus opacus B4
Genome accession: NC_012522
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 7598718 - 7600826 bp
Length : 2109 bp
Strand : -
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
GTGTCGATCACAGACGACATCCACGTCCTCACGCAACCGGTTCATCCCGCCGACTGGACCGAACTGGACACCAAGGCCGT
CGACACCATCCGGGTGCTCGCCGCCGATGCAGTGCAGAAGGTGGGCAACGGCCACCCTGGCACGGCGATGAGCCTCGCCC
CCCTCGCCTACACCCTCTTCCAGCGTGTCATGCGTCACGACCCCACCGACGCCGACTGGATCGGCCGCGACCGGTTCGTG
CTGTCCTGCGGGCACTCCAGCCTCACCCTCTACATCCAGCTGTACCTCGCCGGCTACGGGCTGGAACTGGGCGACCTGGA
GGCATTGCGCACCTGGGGCTCGAAGACCCCCGGACACCCCGAGCACGGCCACACCCGCGGCGTCGAGATCACCACCGGAC
CGCTGGGTCAGGGTCTGGCCTCCGCTGTCGGCATGGCCATGGCCGCCCGCCGTGAGCGCGGCCTGTTCGACCCCGAGCCC
GCGCTGGGCGACAGCCCGTTCGATCACCACATCTACGTGATCGCCTCCGACGGCGACATCGAGGAAGGCGTCACCTCCGA
GGCGTCGTCCATCGCCGGTGTGCAGCAGCTCGGCAACCTGACGCTGGTCTACGACGACAACAAGATCTCCATCGAGGACG
ACACGGCCATCGCGCTGTCCGAGGACACCGCCGCCCGCTACGAGGCGTACGGGTGGCACGTGCAGATCGTCGAGGGCGGC
GAGAACGTCGTCGCCATCGAGGAGGCCCTGAACAAGGCCCGCGAGGTCACCGACAAGCCGTCGCTGATCCTGCTCCGTAC
GATCATCGGCTTCCCCGCACCGACCAAGATGAACACGGGCGCGGCACACGGCGCGGCTCTCGGTGCCGACGAGGTCGCGG
CCGTGAAGAAGGCGCTCGGCTTCGATCCGGACAAGACGTTCGAGGTCGCGGACGAGGTCATCGCCCACACCCGCAAGGTC
GTCGAGCGCGGCGCGCAGGCACACAAGGAATGGCAGGCCCAGTACGACGAGTGGACGCAGCGCGCCCCCGAGGGCAAGAA
GCTGCTCGACCGCCTGATCGGACGCGACCTGCCCGCCGGCTGGGCCGACGTCCTGCCGACGTGGGAGCCCGACGCGAAGG
GTCTCGCCACCCGGAAGGCGTCCGCCGCCGTCCTGAACGCCGTCGGTCCGGTGCTGCCCGAGCTGTGGGGCGGCTCCGCC
GACCTCGCCGAGAGCAACAACACCACCATCAAGGGCGCCGACTCGTTCGGTCCGAAATCCATTTCCACCAGCATGTGGAA
CGCGGAACTCTACGGCCGCACCCTGCACTTCGGTGTCCGCGAGCACGCGATGGGCTCGATCCTCAACGGCATCGCCCTGC
ACGGGCCGACCCGCCCGTACGGCGGCACGTTCCTCGTCTTCAGCGACTACATGCGTCCCGCCGTCCGGCTGGCCGCGATC
ATGAAGACCGCGGTCACCTACGTGTGGACGCACGACTCCATCGGACTCGGCGAGGACGGTCCCACCCACCAGCCGATCGA
GCACCTCGCGGCGCTGCGCGCCATTCCCGGTCTGTACGTCGTGCGGCCCGGCGATGCCAACGAGACCGCGCACGCGTGGC
GCGCCGTTCTCGAGAAGGGCGCGGACGAGGCCACCCGCGCTCCCGCCGGTCTCGCCCTGACCCGTCAGGACCTGCCGGTC
CTCGAAGGCACCAGCTACGAGGGTGTCTCCCGCGGCGGTTACGTCCTCGCCGACGCGTCCACCGGGGCTCCGGAGGTCGT
GCTCATCGGCACGGGCTCCGAGCTGCAGCTGGCCGTCGCCGCGCGCGAGGCCCTCGAGGCGGAGGGCATCCCCACCCGGG
TCGTGTCCGTGCCCTGCGTCGAGTGGTTCGACGCCCAGGACCAGGCCTACCGCGACGGTGTGCTCCCCCCGACCGTCAAG
GCGCGGGTCGCCGTGGAGGCCGGCGTCTCCATGCCGTGGTACCGCTTCGTCGGCGACGCAGGCGAGATCATCTCCATCGA
GCATTTCGGCGCCTCCGCCGACTACAAGACCCTGTTCCGCGAGTTCGGTTTCACCGCCGAAGCCGTCACCGCCGCCGCAC
AGCGCTCGCTCGCACGCGTGAAGGGATAG

Protein sequence :
MSITDDIHVLTQPVHPADWTELDTKAVDTIRVLAADAVQKVGNGHPGTAMSLAPLAYTLFQRVMRHDPTDADWIGRDRFV
LSCGHSSLTLYIQLYLAGYGLELGDLEALRTWGSKTPGHPEHGHTRGVEITTGPLGQGLASAVGMAMAARRERGLFDPEP
ALGDSPFDHHIYVIASDGDIEEGVTSEASSIAGVQQLGNLTLVYDDNKISIEDDTAIALSEDTAARYEAYGWHVQIVEGG
ENVVAIEEALNKAREVTDKPSLILLRTIIGFPAPTKMNTGAAHGAALGADEVAAVKKALGFDPDKTFEVADEVIAHTRKV
VERGAQAHKEWQAQYDEWTQRAPEGKKLLDRLIGRDLPAGWADVLPTWEPDAKGLATRKASAAVLNAVGPVLPELWGGSA
DLAESNNTTIKGADSFGPKSISTSMWNAELYGRTLHFGVREHAMGSILNGIALHGPTRPYGGTFLVFSDYMRPAVRLAAI
MKTAVTYVWTHDSIGLGEDGPTHQPIEHLAALRAIPGLYVVRPGDANETAHAWRAVLEKGADEATRAPAGLALTRQDLPV
LEGTSYEGVSRGGYVLADASTGAPEVVLIGTGSELQLAVAAREALEAEGIPTRVVSVPCVEWFDAQDQAYRDGVLPPTVK
ARVAVEAGVSMPWYRFVGDAGEIISIEHFGASADYKTLFREFGFTAEAVTAAAQRSLARVKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 9e-120 45
tktA AAO17218.1 TktA Not tested tcd island Protein 2e-121 45