Gene Information

Name : nrdF (ROP_64950)
Accession : YP_002783687.1
Strain : Rhodococcus opacus B4
Genome accession: NC_012522
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : 1.17.4.1
Position : 7105397 - 7106362 bp
Length : 966 bp
Strand : +
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
ATGGTCAAGCTGGTGAGTCGCGTATCCGCGATCAACTGGAACCGCGTCCAGGACGAGAAGGACGCCGAGGTGTGGGACCG
TCTCGTCGGCAACTTCTGGCTGCCCGAAAAAGTGCCCGTGTCCAACGACATCCCGTCGTGGGGGACGCTCACGGCGCAGG
AGAAGCAGCTCACGATGCGGGTGTTCACGGGGCTGACGCTCCTCGACACCATTCAGGGCACGGTGGGCGCGGTCAGCCTC
ATCCCCGACGCCATCACGCCGCACGAGGAAGCGGTGTACACCAACATCGCGTTCATGGAGTCGGTGCACGCCAAGAGCTA
CAGCTCGATCTTCTCGACGCTGTGCTCCACTCGCGACATCGACGACGCCTTCCGCTGGTCCGAGGAGAACCCGAACCTGC
AGCGCAAGGCCGAGATCGTCATGGACTACTACCAGGGCGACGAGCCGCTCAAGCGCAAGGTGGCATCCACCCTGCTCGAG
AGCTTCCTGTTCTACTCCGGCTTCTACCTGCCGATGTACTGGTCGTCGCGGGCGAAGCTCACCAACACCGCCGATCTCAT
CCGTCTCATCATCCGTGACGAGGCCGTGCACGGGTACTACATCGGCTACAAGTACCAGAAGGGTCTCGAGCAGCTCACCG
AGGCGGAGCGCGACGACCTCAAGAACTACACGTTCGAGTTGCTCTTCGAGCTGTACGACAACGAGGTCGACTACACCCAG
GACCTTTACGACGAGGTGGGCCTCACCGAGGACGTCAAGAAGTTCCTGCGGTACAACGCCAACAAGGCACTGATGAACCT
CGGCTACGAGGGTCTGTTCCCGAAGGACGAGACGGACGTCAACCCGGCGATCCTGTCGGCGCTCTCACCCAACGCGGACG
AGAATCACGACTTCTTCTCCGGCTCGGGCAGCTCCTACGTCATCGGCAAGGCCGTCAACACCGAAGACGAAGACTGGGAT
TTCTAG

Protein sequence :
MVKLVSRVSAINWNRVQDEKDAEVWDRLVGNFWLPEKVPVSNDIPSWGTLTAQEKQLTMRVFTGLTLLDTIQGTVGAVSL
IPDAITPHEEAVYTNIAFMESVHAKSYSSIFSTLCSTRDIDDAFRWSEENPNLQRKAEIVMDYYQGDEPLKRKVASTLLE
SFLFYSGFYLPMYWSSRAKLTNTADLIRLIIRDEAVHGYYIGYKYQKGLEQLTEAERDDLKNYTFELLFELYDNEVDYTQ
DLYDEVGLTEDVKKFLRYNANKALMNLGYEGLFPKDETDVNPAILSALSPNADENHDFFSGSGSSYVIGKAVNTEDEDWD
F

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 4e-114 74