Gene Information

Name : nrdE (ROP_64940)
Accession : YP_002783686.1
Strain : Rhodococcus opacus B4
Genome accession: NC_012522
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : 1.17.4.1
Position : 7103196 - 7105331 bp
Length : 2136 bp
Strand : +
Note : Catalyzes the rate-limiting step in dNTP synthesis

DNA sequence :
GTGGCACGACCCGACGTCTCCTCGGGAGAACTCGATTACCACGCGTTGAACGCGATGCTGAACCTGTACGGCCCCAACGG
CGAGATCCAGTTCGAGAAGGACCGCGAGGCCGCGAACCAGTACTTCCTCCAGCACGTCAACCAGAACACCGTCTTCTTCC
ACAACCAGGACGAGAAGCTGGACTACCTGGTGAAGGAGAACTACTACGAGCGCGAGGTCCTCGACCAGTACACGCGCAAC
TTCGTCAAGTCGCTGATCGACCACGCGTACTCGAAGAAGTTCCGGTTCCCCACCTTCCTCGGTGCATTCAAGTACTACAC
GTCGTACACGCTGAAGACGTTCGACGGCAAGCGGTACCTCGAGCGGTTCGAGGACCGGGTCTGCATGGTCGCGCTCACCC
TCGCCGCAGGCGACGAGGAGCTGGCGACCAAGCTCGTCGACGAGATCATCGCCGGCCGCTTCCAGCCCGCCACCCCCACG
TTCCTCAACTCGGGCAAGAAGCAGCGCGGCGAGCCCGTGTCCTGTTTCCTGCTCCGCATCGAGGACAACATGGAGTCGAT
CGGCCGCTCCATCAACTCCGCCCTGCAGCTGTCCAAACGCGGCGGCGGAGTTGCGTTGCTGCTCAGCAATGTTCGCGAAC
ACGGCGCCCCGATCAAGAAGATCGAGAACCAGAGCTCCGGGGTCATCCCGATCATGAAGCTGCTCGAGGACTCCTTCTCG
TACGCCAATCAGCTCGGTGCGCGTCAGGGCGCAGGCGCGGTGTACCTGCATGCGCACCACCCGGACATCTACCGCTTCCT
CGACACCAAGCGCGAGAACGCGGACGAGAAGATCCGCATCAAGACGCTGTCGCTGGGCGTCGTCATCCCCGACATCACGT
TCGAGCTGGCGAAGAAGAACGAGGACATGTACCTCTTCTCGCCGTACGACGTCGAGCGCATCTACGGGGTGCCCTTCGCG
GACATCAACGTCACCGAGAAGTACTACGAGATGGTCGACGACAAGCGGATCCGCAAGTCGAAGATCAAGGCACGCGAGTT
CTTCCAGACCGTGGCCGAGCTGCAGTTCGAGTCCGGGTACCCGTACATCATGTACGAGGACACCGTGAACCGGGCCAACC
CGATCGCGGGCAAGGTCACCCACTCCAACCTGTGCTCGGAGATTTTGCAGGTCTCCACGCCGTCGGAGTTCAACGACGAC
CTGTCCTACAGTCATATCGGCAAGGACATCTCCTGCAACCTGGGTTCGCTCAACATCGCCAAGACGATGGACTCGCCGGA
CTTCGCGCAGACCATCGAGACCTCGATCCGGGCGCTGACCGCCGTCGCCGATCAGACCTCCATCGACTCGGTCCCGTCGA
TCAAGAAGGCGAACGACGAGGGACACGCCATCGGTCTCGGGCAGATGAACCTGCACGGATACCTGGCACGCGAGCGGATC
CACTACGGCTCCGACGAGGGCATCGATTTCACGAACATCTACTTCTACACCGTGGTGTTCCACGCGATCCGGGCGTCCAA
CGAGATCGCCAAGGAGCGCGGCACGTACTTCGCCGGCTTCCCGGAGTCCAAGTACGCCTCGGGTGAGTACTTCGACAAGT
ACACCGATCAGGTGTGGGAACCGAAGACGGAGCGGGTGCGGCAGCTGTTCGCCGATGCGGGCCTGCACATCCCGACCCAG
GACGACTGGCGTGAGCTGAAGGCGTCCGTGCAGCAGCACGGCATTTACAACCAGAACCTACAGGCGGTGCCGCCGACCGG
ATCGATCTCATATATCAACAACTCCACCAGCTCCATTCACCCGGTGGCGTCGAAGATCGAGATCCGCAAGGAAGGCAAGA
TCGGCCGCGTCTACTACCCGGCGCCCTACCTGACCAACGACAACCTGGAGTACTACCAGGATGCGTACGAGATCGGGTAC
GAGAAGATCATCGACACCTACGCCGCGGCCACCCAGCACGTGGACCAGGGCTTGTCGCTGACGCTGTTCTTCAAGGACAC
CGCCACCACCCGCGACATCAACAAGGCGCAGATCTACGCGTGGCGCAAGGGAATCAAGACGCTGTACTACATCCGTCTAC
GTCAGATGGCCCTCGAGGGCACTGAGGTGGAGGGCTGCGTCAGCTGCATGCTGTAG

Protein sequence :
MARPDVSSGELDYHALNAMLNLYGPNGEIQFEKDREAANQYFLQHVNQNTVFFHNQDEKLDYLVKENYYEREVLDQYTRN
FVKSLIDHAYSKKFRFPTFLGAFKYYTSYTLKTFDGKRYLERFEDRVCMVALTLAAGDEELATKLVDEIIAGRFQPATPT
FLNSGKKQRGEPVSCFLLRIEDNMESIGRSINSALQLSKRGGGVALLLSNVREHGAPIKKIENQSSGVIPIMKLLEDSFS
YANQLGARQGAGAVYLHAHHPDIYRFLDTKRENADEKIRIKTLSLGVVIPDITFELAKKNEDMYLFSPYDVERIYGVPFA
DINVTEKYYEMVDDKRIRKSKIKAREFFQTVAELQFESGYPYIMYEDTVNRANPIAGKVTHSNLCSEILQVSTPSEFNDD
LSYSHIGKDISCNLGSLNIAKTMDSPDFAQTIETSIRALTAVADQTSIDSVPSIKKANDEGHAIGLGQMNLHGYLARERI
HYGSDEGIDFTNIYFYTVVFHAIRASNEIAKERGTYFAGFPESKYASGEYFDKYTDQVWEPKTERVRQLFADAGLHIPTQ
DDWRELKASVQQHGIYNQNLQAVPPTGSISYINNSTSSIHPVASKIEIRKEGKIGRVYYPAPYLTNDNLEYYQDAYEIGY
EKIIDTYAAATQHVDQGLSLTLFFKDTATTRDINKAQIYAWRKGIKTLYYIRLRQMALEGTEVEGCVSCML

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 0.0 78