Gene Information

Name : smpB (ROP_64660)
Accession : YP_002783658.1
Strain : Rhodococcus opacus B4
Genome accession: NC_012522
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 7080554 - 7081027 bp
Length : 474 bp
Strand : +
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
GTGAAGGAAAAGGGCCGCAAGGTCATTGCGACCAATCGCAAGGCGCGTCACAACTACACCATTCTCGACGTCTACGAGGC
GGGGATCGCCCTCGTCGGGACCGAGGTGAAGAGTCTGCGCGAGGGCAAGGCGTCGCTGGTCGACGCGTTCGCCACCGTCG
ACGACGGGGAGGTGTGGCTGCGCTCCCTGCACATCCCCGAGTACACGCAGGGCACGTGGACCAACCACTCGCCGCGCCGC
ACCCGGAAGTTGCTACTGCACAAGCGGGAGATCGAGCACCTCGTCGGCAAGACCCGCGAGGGAAACCAGACTCTGGTTCC
CCTGTCGATGTACTTCTCCGACGGCAAGGTCAAGGTGGAACTCGCGCTCGCCAAGGGCAAGCAGGACTACGACAAGCGCC
AGGACCTGGCCAGGCGGACCGCCGAGCGTGAGGTGACCCGCGAACTCGGACGCCGAGTCAAGGGCATGCGCTGA

Protein sequence :
MKEKGRKVIATNRKARHNYTILDVYEAGIALVGTEVKSLREGKASLVDAFATVDDGEVWLRSLHIPEYTQGTWTNHSPRR
TRKLLLHKREIEHLVGKTREGNQTLVPLSMYFSDGKVKVELALAKGKQDYDKRQDLARRTAEREVTRELGRRVKGMR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 1e-48 72
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 1e-29 54
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 2e-20 44