Gene Information

Name : guaA (ROP_62620)
Accession : YP_002783454.1
Strain : Rhodococcus opacus B4
Genome accession: NC_012522
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 6866038 - 6867609 bp
Length : 1572 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
GTGGCAGATATCGAGCAGCAGAGACCGGTCCTCGTCGTCGACTTCGGCGCGCAGTACGCGCAGCTGATCGCCCGGCGGGT
GCGTGAGGCCAAGGTCTATTCCGAGGTGGTCCCGCACACCGCGACCGTCGAGGAGATCGCGGCCAAGAATCCGCTCGCCG
TGGTGCTGTCGGGCGGACCGTCCAGCGTCTACGCCGACGGGGCGCCCCAGCTCGATCCGGCCCTGTTCGATCTGGACGTT
CCGGTGTTCGGCATCTGCTACGGATTCCAGGCCATGGCCGGTGCACTGGGCGGGACGGTGGCCCACACCGGCACCCGCGA
GTACGGCCGCACCGACCTGAAGGTGCAGGGCGGCCTGCTGCACGAGGGGCTGCCGTCCAGTCAGCCCGTGTGGATGAGCC
ACGGCGACGCGGTCACAGAGGCCCCCGAAGGTTTCGAGGTGACGGCCACGAGTGAGGGCGCACCCGTCGCCGCATTCGAG
GACCGGGCCCGCAGGCTCGCGGGCGTGCAGTACCACCCGGAGGTCCTGCACTCGCCGCACGGCCAGCAGGTGCTCAGCCG
GTTCCTCCACGAGATCGCCGGCATTCCCCCCGCGTGGACGGCCGCGAATATCGCCGACGCCCTCGTGGAGCAGGTCCGCG
AGCAGGTGGGCGACGGCAAGGCGATCTGCGGACTCTCGGGCGGTGTCGACTCCGCCGTCGCGGCCGCGCTCGTGCAGCGT
GCGATCGGCGACAACCTGACGTGTGTGTTCGTCGACCACGGTCTGATGCGTGCCGGCGAGCGCGCGCAGGTCGAGCAGGA
TTTCGTCGCCGCCACCGGCGCCCGGCTCATCACCGTCGACGCCGCCGACACCTTCATCGGTGAACTGGCAGGGGTGTCCG
ACCCGGAGACCAAGCGCAAGATCATCGGCCGCGAGTTCATCCGCAGCTTCGAGGGTGCCGTCAGCGACGTGCTCGGCGAG
AACGCCGCGCACGGCGACACGGTCGAATTCCTCGTGCAGGGCACGCTCTACCCGGACGTCGTGGAATCCGGCGGTGGTAC
CGGCACGGCCAACATCAAGAGCCACCACAACGTCGGCGGGCTGCCCGAAGACCTGCAGTTCACGCTCGTGGAACCGCTGC
GTCTGCTGTTCAAGGACGAGGTCCGCGCGGTGGGACGGGAGCTCGGTCTGCCCGAGGAGATCGTGGGACGTCAGCCGTTC
CCCGGCCCCGGGCTCGGCATCCGCATCATCGGCGAGGTCACCCAGGAGCGGCTCGACCTGCTTCGTCACGCGGATTCCAT
TGCGCGCGAAGAGTTGACGGCAGCCGGGCTCGACGGCCAGATCTGGCAGTGCCCGGTGGTGCTGCTCGCCGACGTCCGCA
GCGTCGGCGTACAGGGCGACGGGCGCACCTACGGGCACCCGATCGTGCTCCGTCCCGTGTCCAGCGAGGACGCGATGACC
GCCGACTGGACGCGACTGCCCTACGACGTCCTGGAGCGGATCTCCACCCGGATCACGAACGAGGTCCACGACGTCAACCG
GGTCGTGCTGGACATCACGAGCAAGCCGCCGGGCACCATCGAGTGGGAGTGA

Protein sequence :
MADIEQQRPVLVVDFGAQYAQLIARRVREAKVYSEVVPHTATVEEIAAKNPLAVVLSGGPSSVYADGAPQLDPALFDLDV
PVFGICYGFQAMAGALGGTVAHTGTREYGRTDLKVQGGLLHEGLPSSQPVWMSHGDAVTEAPEGFEVTATSEGAPVAAFE
DRARRLAGVQYHPEVLHSPHGQQVLSRFLHEIAGIPPAWTAANIADALVEQVREQVGDGKAICGLSGGVDSAVAAALVQR
AIGDNLTCVFVDHGLMRAGERAQVEQDFVAATGARLITVDAADTFIGELAGVSDPETKRKIIGREFIRSFEGAVSDVLGE
NAAHGDTVEFLVQGTLYPDVVESGGGTGTANIKSHHNVGGLPEDLQFTLVEPLRLLFKDEVRAVGRELGLPEEIVGRQPF
PGPGLGIRIIGEVTQERLDLLRHADSIAREELTAAGLDGQIWQCPVVLLADVRSVGVQGDGRTYGHPIVLRPVSSEDAMT
ADWTRLPYDVLERISTRITNEVHDVNRVVLDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 0.0 80
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 5e-137 52
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 4e-137 52
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 4e-137 52