Gene Information

Name : ROP_48840 (ROP_48840)
Accession : YP_002782076.1
Strain : Rhodococcus opacus B4
Genome accession: NC_012522
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : 6.3.2.-
Position : 5260426 - 5262078 bp
Length : 1653 bp
Strand : -
Note : -

DNA sequence : 
ATGACCACGAGCGTTCGCGCTCCCCTGGAGACCACCACCGGCTATCCCGCCGAACTCGTCGCACGCTACCGTGCCGCCGG
GTACTGGACGGACGAGACGTTCCAGCAGTTTCTGGGCGCCCGCGCCGAGCGATTCGGGGACGCGATCGCCGTGACCGGGC
CGGACGCGTCCGGGTCCGACCGCGCCCTCACCTACCGCGAATTGTCCGACCGCGCCGACCGGCTCGCCGCCGGTCTGCAG
TCGTCGGGGGTGCAGCCCGGCGACCGGGTGGTGGTGCAACTGCCGAACATCGTCGAGTACGTCGAGGTGATCTTCGCGGT
CTTCCGGCTCGGCGCCCTGCCGGTGTTCGCGCTGCCCGCGCACCGCTCCCAGGAGATCTCCTACTTCTGCAGTTTCGCCG
ACGCGGCGGCCTACGTGATCACCGACACGCACGCCGGTTTCGACTACCGGGGCCTCGCCCGCGACGTAGTGTCGTCGGCG
GCGAACCCGCCGCGGGTCATCGTGGCAGGCGACGCGGAGGAGTTCACCTCCCTCGACGAACTGCGGGCCTCGGAACCGAT
CTCGGACGCACCGGCGGCCGGTCCGGAATCCGTGGCGTTCCTGCAGCTCTCGGGCGGAACCACCGGGGTGTCGAAGCTGA
TCCCGCGCACCCATACCGACTACCTGTACTCGGTGCGCGAGTCGGACCGCATCTGCGGCATCGACGAAAACACCCGCCTG
CTGGTCGCCCTCCCTGCGGCGCACAACTTCCCGATGAGCTCCCCGGGCATCCTCGGCGTGCTGCACGCCGGTGGCCGCGT
GGTGCTCGCCCCGGATCCCAGTCCCGACACCGCGTTCGCGCTCATCGAGCGGGAGAGAGTCACGATCGCGTCGCTGGTCC
CGCCGCTCGCGCTGGCGTGGCTGTCCGCCGCCGCCCGCACGGACCGGGACATCTCGAGCCTCGAGGTGCTGCAGGTCGGG
GGCGCGAAGTTCAGCGCCGAGGCCGCCAAGCGGGTGCGTCCCGAACTCGGGTGCGCGCTGCAGCAGGTCTTCGGGATGGC
CGAGGGACTGGTCAACTACACAAGGCTGGACGACCCGGAAGAGACGATCGTCACCACCCAGGGCAGGCCGATCAGCCCCG
ACGACGAGGTGCGGGTCGTCGACGACCAGGGTGCGCCCGTCCCGACCGGCACGTCCGGTCACCTGCTCACCCGCGGTCCG
TACACCATCCGCGGCTACTACCGCGCCCCCGAACACAATTCGACCGCGTTCACCGAGGACGGTTTCTACCGCACCGGCGA
CATCGTCCGGCTCACCGACGACGGCTACCTCGTGGTCGAGGGCCGCGCGAAGGATCAGATCAACCGCGGCGGCGAGAAGG
TGGCCGCCGAGGAGGTCGAGAATCACCTGCTCGCGCACCCAGCCGTCGCCGACGTCGCGGTGGTGTCGATGCCCGATCAG
TATCTCGGCGAACGCAGTTGCGCGTTCGTCGTCGTCGCGGGCGAGCAGCCGAAGGCCGTCGAGCTCAAGAAGTTCGTCCG
CGGCCGCGGACTCGCCGACTACAAGGTCCCCGACAAGGTCGTGTTCGTCGACGAGTTCCCGGTCACCGGTGTCGGCAAGA
TCAGCAAGTCGGAACTGCGCCGGGCCCTGGAGAAGACGTTCGTCACGTCCTGA

Protein sequence : 
MTTSVRAPLETTTGYPAELVARYRAAGYWTDETFQQFLGARAERFGDAIAVTGPDASGSDRALTYRELSDRADRLAAGLQ
SSGVQPGDRVVVQLPNIVEYVEVIFAVFRLGALPVFALPAHRSQEISYFCSFADAAAYVITDTHAGFDYRGLARDVVSSA
ANPPRVIVAGDAEEFTSLDELRASEPISDAPAAGPESVAFLQLSGGTTGVSKLIPRTHTDYLYSVRESDRICGIDENTRL
LVALPAAHNFPMSSPGILGVLHAGGRVVLAPDPSPDTAFALIERERVTIASLVPPLALAWLSAAARTDRDISSLEVLQVG
GAKFSAEAAKRVRPELGCALQQVFGMAEGLVNYTRLDDPEETIVTTQGRPISPDDEVRVVDDQGAPVPTGTSGHLLTRGP
YTIRGYYRAPEHNSTAFTEDGFYRTGDIVRLTDDGYLVVEGRAKDQINRGGEKVAAEEVENHLLAHPAVADVAVVSMPDQ
YLGERSCAFVVVAGEQPKAVELKKFVRGRGLADYKVPDKVVFVDEFPVTGVGKISKSELRRALEKTFVTS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 2e-107 48
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 9e-107 48
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 1e-107 48
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-106 48
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-107 48
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 2e-107 48
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-107 48
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-107 48
ybtE CAA21394.1 - Virulence HPI Protein 2e-107 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ROP_48840 YP_002782076.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 2e-131 53
ROP_48840 YP_002782076.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 3e-113 49
ROP_48840 YP_002782076.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 2e-114 47