Gene Information

Name : clpC (ROP_43390)
Accession : YP_002781531.1
Strain : Rhodococcus opacus B4
Genome accession: NC_012522
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit ClpC
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 4680794 - 4683331 bp
Length : 2538 bp
Strand : +
Note : -

DNA sequence :
ATGTTCGAGAGGTTCACCGATCGCGCACGGCGCGTTGTTGTCCTGGCTCAAGAAGAAGCCAGGATGCTCAACCACAACTA
CATCGGTACGGAGCACATCCTGCTCGGCCTCATTCACGAGGGCGAAGGTGTCGCTGCCAAGTCGCTGGAGTCGTTGGGCA
TCTCCCTCGAAGGAGTGCGCAGCCAGGTCGAGGAGATCATCGGCCAGGGCCAGCAGGCCCCGTCCGGCCACATCCCCTTC
ACCCCGCGTGCCAAGAAAGTCCTGGAGCTCAGCCTGCGCGAGGCACTGCAGCTCGGACACAACTACATCGGTACGGAGCA
CATCCTGCTCGGCCTCATCCGCGAGGGTGAAGGCGTCGCAGCGCAGGTTCTGGTGAAGCTCGGTGCCGACCTCAACCGGG
TCCGTCAGCAGGTCATCCAGCTGCTTTCCGGTTACCAGGGCAAGGAGCCTGCCGAGTCCGGCGGCACTCGTGGCGAGGCG
GGCACCCCGTCCACGTCGCTGGTGCTCGACCAGTTCGGTCGCAACCTCACCCAGGCGGCCCTCGAAGGCAAGCTCGACCC
CGTCATCGGCCGCTCGAAGGAAATCGAGCGCGTCATGCAGGTCCTGTCGCGCCGTACCAAGAACAACCCCGTGCTGATCG
GTGAGCCGGGTGTCGGTAAGACCGCCGTCGTCGAAGGTCTCGCTCAGGCCATCGTCAACGGCGAGGTCCCCGAGACGCTC
AAGGACAAGCAGCTGTACACGCTCGACCTCGGGTCGCTCGTGGCAGGCAGCCGTTACCGCGGTGACTTCGAAGAGCGCCT
GAAGAAGGTCCTCAAGGAGATCAACACCCGCGGCGACATCATCCTGTTCATCGACGAGCTGCACACCCTGGTGGGTGCCG
GCGCGGCCGAGGGCGCCATCGATGCGGCCTCGATCCTCAAGCCGAAGCTCGCCCGCGGTGAGCTGCAGACCATCGGTGCG
ACCACCCTCGACGAATACCGCAAGTACATCGAGAAGGACGCCGCGCTCGAGCGCCGCTTCCAGCCGGTGCAGGTCGGCGA
GCCGACGGTGGAGCACACCATCGAGATCCTCAAGGGTCTGCGCGACCGTTACGAGGCGCACCACCGCGTGTCCATCACGG
ACGGTGCACTCGTCGCCGCGGCCACCCTGGCCGACCGCTACATCAACGACCGCTTCCTGCCGGACAAGGCCATCGACCTC
ATCGACGAGGCCGGAGCACGGATGCGCATCCGCCGGATGACCGCGCCGCCGGACCTCCGCGAGTTCGACGACAAGATCGC
GGACGCCCGCCGCGAGAAGGAGTCCGCGATCGACGCGCAGGACTTCGAGAAGGCCGCGAACCTGCGCGACAAGGAGAAGA
CCCTCGTCGCTCAGCGCGCGGAGCGGGAGAAGCAGTGGCGTTCCGGTGACCTGGACGTCATCGCCGAGGTCGACGACGAG
CAGATCGCCGAGGTCCTGGGTAACTGGACCGGTATCCCCGTGTTCAAGCTCACCGAGGAGGAGACCACCCGTCTGCTCCG
CATGGAGGAGGAGCTGCACAAGCGGATCATCGGTCAGGAAGACGCGGTCAAGGCTGTCGCCAAGGCCATCCGTCGTACCC
GCGCCGGCCTGAAGGACCCGAAGCGTCCGTCCGGTTCGTTCATCTTCGCCGGCCCGTCCGGTGTCGGTAAGACCGAGCTG
GCCAAGTCGCTCGCCAACTTCTTGTTCGGCGAGGACGACGCCCTCATCCAGATCGACATGGGCGAGTTCCACGACCGCTT
CACGGCGTCGCGGCTGTTCGGTGCCCCTCCCGGCTACGTCGGCTACGAAGAGGGCGGCCAGCTCACCGAGAAGGTGCGCC
GCAAGCCGTTCAGCGTGGTGCTGTTCGACGAGATCGAGAAGGCACACCAGGAGATCTACAACACGCTCCTGCAGGTGCTC
GAGGACGGCCGTCTCACCGACGGTCAGGGCCGGACCGTGGACTTCAAGAACACGGTGCTCATCTTCACCTCGAACCTCGG
CACGTCGGACATCTCCAAGGCCGTGGGTCTCGGCTTCACGTCCGGCAAGGGCGACGAGTCGAACTACGAGCGGATGAAGC
TCAAGGTGCACGACGAGCTGAAGAAGCACTTCCGTCCCGAGTTCCTCAACCGCATCGACGACATCGTCGTGTTCCACCAG
CTCACCACCGAGCAGATCGTTCAGATGGTGGACCTGATGGTCGCGCGCGTCGAGGTGGCCTTGAAGAACAAGGACATGAC
GATGGAGGTCAGCGAGAAGGCCAAGGCGCTGCTGGCCAAGCGTGGCTTCGATCCGGTCCTGGGTGCACGGCCGCTGCGTC
GCACCATCCAGCGCGAGATCGAGGATCAGCTGTCGGAGAAGATCCTCTTCGGCGAGGTCGGACCCGGTCAGATCGTGTAC
GTCGACGTCGACAACTGGGACGGTGAAGGCGCGGGCGAGGACGCGAAGTTCACGTTCCGCGGCGAGGCGAAGCCGGTCAC
GGTTCCCGACGAGGTTCCGGTCGACTTGGCGAAGTCGGGCGCAGCCGACTCGGAGTAG

Protein sequence :
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVRSQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGADLNRVRQQVIQLLSGYQGKEPAESGGTRGEA
GTPSTSLVLDQFGRNLTQAALEGKLDPVIGRSKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVNGEVPETL
KDKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEGAIDAASILKPKLARGELQTIGA
TTLDEYRKYIEKDAALERRFQPVQVGEPTVEHTIEILKGLRDRYEAHHRVSITDGALVAAATLADRYINDRFLPDKAIDL
IDEAGARMRIRRMTAPPDLREFDDKIADARREKESAIDAQDFEKAANLRDKEKTLVAQRAEREKQWRSGDLDVIAEVDDE
QIAEVLGNWTGIPVFKLTEEETTRLLRMEEELHKRIIGQEDAVKAVAKAIRRTRAGLKDPKRPSGSFIFAGPSGVGKTEL
AKSLANFLFGEDDALIQIDMGEFHDRFTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNTLLQVL
EDGRLTDGQGRTVDFKNTVLIFTSNLGTSDISKAVGLGFTSGKGDESNYERMKLKVHDELKKHFRPEFLNRIDDIVVFHQ
LTTEQIVQMVDLMVARVEVALKNKDMTMEVSEKAKALLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFGEVGPGQIVY
VDVDNWDGEGAGEDAKFTFRGEAKPVTVPDEVPVDLAKSGAADSE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 82
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 1e-89 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_002781531.1 ATP-dependent Clp protease ATP-binding subunit ClpC VFG0079 Protein 0.0 60
clpC YP_002781531.1 ATP-dependent Clp protease ATP-binding subunit ClpC VFG0080 Protein 3e-144 52