Gene Information

Name : serS (ROP_39200)
Accession : YP_002781112.1
Strain : Rhodococcus opacus B4
Genome accession: NC_012522
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 4225271 - 4226527 bp
Length : 1257 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
GTGATTGACCTGAAGTTCCTCCGCGAGAACCCCGACGCCGTCCGCGAATCGCAGCGCACCCGTGGCGAAGATCCCGCCCT
GGTCGACGCGTTGCTCGAGGCCGACGCGTCCCGTCGCGCCGCCGTTCTCGCCGGCGACAACCTGCGTGCCGAGCAGAAGG
CGTTCGGCAAGAAGGTCGGGCAGGCGTCCCCGGAGGAGCGCCCGGCGCTGCTCGAGGGATCCAAGGAACTCGCGGCCAAG
GTGAAGCAGGCCGAGGCCGGCCAGCACGAGGCGCAGGCCGCGCTCGACGCCGCACACCGGGCGATCTCCAACATCGTCCA
GGACGGCGCCCCCGCCGGCGGTGAGGACGACTTCATCACCCTCGAGACGGTCGGGGAGATCCCCGCATTCGACTTCGAAC
CCAAGGACCACCTCGAGCTGGGTGAGTCGCTGGGGCTGATCGACATGGAGCGCGGCGCGAAGGTGTCAGGCGCCCGCTTC
TACTTCCTCACCGGCTTCGGTGCCATGCTGCAGCTGGGAATGCTGCAGCTCGCCGCACAGAAGGCGATGGCCAACGGTTT
CCAGATGATGATCCCGCCGGTGCTGGTGCGCCCGGAGATCATGGCGGGAACCGGGTTCCTCGGCGCCCACTCGGACGAGA
TCTACCACCTCGCCGACGACGACCTCTACCTCGTCGGCACGTCCGAGGTCCCGCTGGCCGGGTACCACTCCGGGGAGATC
CTCGACCTCGCCGACGGCCCCAAGCGGTACGCCGGCTGGTCGACGTGCTTCCGCCGCGAGGCAGGCAGCTACGGCAAGGA
CACCCGCGGCATCATCCGCGTCCACCAGTTCGACAAGGTGGAGATGTTCACCTACTGCAAGCCCGAGGACGCCGACGCCG
AGCACCAGCGCCTCCTCGCGTGGGAGCGCGACATGCTCGCCGCCATCGACGTGCCGTACCGCGTGATCGACGTGGCCGGC
GGCGACCTGGGATCGTCGGCGGCCCGCAAGTTCGACTGCGAGGCGTGGGTGCCGACGCAGCAGGCGTACCGGGAGCTCAC
GTCGACGTCCAACTGCACGACGTTCCAGGCGCGTCGCCTCGGGGTGCGGTACCGCGACGAGAACGGGAAGCCGCAGACGG
CCGCGACCCTCAACGGCACCCTCGCCACTACCCGGTGGATCGTCGCCATCCTGGAGAACCACCAGCAGTCCGACGGCACA
GTGCGGGTGCCCGAGGCGCTCGTGCCGTTCGTCGGGACGGATGTTCTGAAACCGTGA

Protein sequence :
MIDLKFLRENPDAVRESQRTRGEDPALVDALLEADASRRAAVLAGDNLRAEQKAFGKKVGQASPEERPALLEGSKELAAK
VKQAEAGQHEAQAALDAAHRAISNIVQDGAPAGGEDDFITLETVGEIPAFDFEPKDHLELGESLGLIDMERGAKVSGARF
YFLTGFGAMLQLGMLQLAAQKAMANGFQMMIPPVLVRPEIMAGTGFLGAHSDEIYHLADDDLYLVGTSEVPLAGYHSGEI
LDLADGPKRYAGWSTCFRREAGSYGKDTRGIIRVHQFDKVEMFTYCKPEDADAEHQRLLAWERDMLAAIDVPYRVIDVAG
GDLGSSAARKFDCEAWVPTQQAYRELTSTSNCTTFQARRLGVRYRDENGKPQTAATLNGTLATTRWIVAILENHQQSDGT
VRVPEALVPFVGTDVLKP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 3e-60 41