Gene Information

Name : leuS (ROP_34430)
Accession : YP_002780635.1
Strain : Rhodococcus opacus B4
Genome accession: NC_012522
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 3730018 - 3732855 bp
Length : 2838 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
GTGACCGAGCACGTGCAGCCCGCCAACCCGTCCGACGCGACCCCGCAGCACCGCTACACCGCGGAGCTCGCCGGCCAGAT
CGAGCAGCGCTGGCAGGACCGGTGGAGCGAGGAGGGCACGTTCGACGCGCCCAACCCGGTCGGCCCCCTCGCCGGCGACG
TTCCCGCGGACAAGCTGTTCGTGCAGGACATGTTCCCGTACCCGTCGGGGACGGGCCTGCACGTGGGCCACCCGCTCGGC
TACATCGCCACCGACGTGTTCGCCCGCTACCACCGCATGCAGGGCCACAACGTGCTGCACACCCTCGGCTACGACGCGTT
CGGTCTGCCTGCCGAGCAGTACGCGGTGCAGACGGGCACGCACCCGCGGACCACCACCGAGGCCAACATCGGCAACATGA
AGCGGCAGCTGCGTCGCCTCGGGCTCGGTCACGACGAGCGCCGCACGTTCGCGACCACCGACGTCGACTTCTACCATTGG
ACGCAGTGGATCTTCCTGCAGATCCACGACGCGTGGTTCGACAAGGAGGCAGGCAAGGCCCGGCGCATCTCGGAGCTCGA
GGCCGAGTTCGTCTCGGGTGCGCGCGCCCTGGAAGACGGACGGGACTGGGCGTCGCTGCCGGCGACCGAGAAGGAAGCGG
TCCTCGACTCCTACCGCCTCGTGTACCACTCCGATTCGATGGTCAACTGGTGCCCCGGTCTGGGCACCGTGCTGGCCAAC
GAGGAGGTCACCGCCGACGGTCGCAGCGACCGCGGAAACTTCCCCGTGTTCCGTAAGCACCTGCAGCAGTGGATGATGCG
CATCACCGCGTACTCCGACCGCCTGGTGGACGACCTCGAGTACCTGGACTGGCCGGAGAAGGTCAAGACCATGCAGCGCA
ACTGGATCGGGCGCTCGCACGGTGCGCAGGTGCGGTTCGATGCGAACGGTCACGGCATCGAGGTGTTCACGACGCGGCCG
GACACGTTGTTCGGTGCGACGTACGTGACGCTGGCGCCGGAGCACGAACTGGTGGACGAGATCGTCGCGGCCGCGTGGCC
GGAGGGTGTGGACGCCCGCTGGACCGGCGGTGCCGCAACGCCCGGCGAAGCGGTTGCAGCATACCGAAAGTCGATCGCCG
CCAAGTCGGATCTGGAGCGGCAGGAATACAAGGAGAAGACGGGCGTCTTCCTCGGCACGTACGCCGTGAACCCCGTCAAC
GGTCACAAGCTGCCGGTATTCATCGCCGACTACGTCCTCACCGGCTACGGCACGGGCGCCATCATGGCCGTCCCCGGTCA
CGACCACCGCGACTACGAGTTCGCCACCGAGTTCGGTCTCGACATCGTCGAGGTGATCTCCGGCGGCGACCTCTCCAAGG
ACGCGTACACCGGTGACGGCACTATCGTGAACTCCGACTTCCTGAACGGCATGTCCGTCACCGACGCGAAGAAGGCCATC
ACCGACCGGCTCGAGGCGGACGGCACCGGCAAGGGCACCATCCAGTACAAGCTGCGCGACTGGCTGTTCGCGCGGCAGCG
GTACTGGGGCGAGCCGTTCCCGATCGTGTACGACGCCGACGGCAACGCGCACGCCCTGCCGGAATCGGCTCTGCCCGTGG
AGCTTCCGGAGGTCGAGGACTACGCACCCGTGTCGTTCGATCCCGACGACGCGTCCTCGGAGCCCTCTCCCCCGCTGGCG
AAGGCCGTCGACTGGGTCAACGTCGAACTCGACCTCGGCGACGGACTGCAGACGTATCGCCGCGACACCAACGTGATGCC
GCAGTGGGCGGGCAGTTCGTGGTACCAGCTGCGCTACATCGACCCCACCAACCCGGACGTGTTCTGCGACAAGGAGAACG
AGCGGTACTGGACGGGTCCGCGGCCGGAGATCCACGGGCCGAACGATCCCGGCGGCGTCGACCTGTACGTCGGTGGTGTC
GAGCACGCGGTGCTGCACCTGCTGTATTCGCGGTTCTGGCACAAGGTGCTGTTCGACCTCGGGTACGTCAGCTCGAGCGA
GCCGTACCGCCGCCTGTACAACCAGGGTTACATCCAGGCCTACGCCTACACCGATGCGCGCGGCGTGTACGTGCCCGCCG
ACGAGGTGGAGGAGAAGGACGGCAAGTTCTTCCACCAGGGCGCCGAGGTCAACCGCGAGTACGGGAAGATGGGCAAGAGC
CTCAAGAACTCCGTGTCGCCGGACGACATCTGTGAGGAGTACGGCGCCGACACGCTCCGCGTGTACGAGATGTCGATGGG
CCCGCTGGACACGTCCCGCCCGTGGGCGACCAAGGACGTCGTCGGTGCGCAGCGCTTCCTGCAGCGCGCCTGGCGTGTCG
TCGTCGACGAGGAGTCCGGGGCCGTGCGCGTCACCGACGACGCCCCGACGGAGGACACGCTGCGCGCGTTGAACAAGGCG
ATCGCCGGTGTCGGTGAGGACTACACCGCACTGCGCGACAACACGGCCGCCGCCAAGCTGATCGAGTACACCAACCACCT
CACCAAGGCGTACCCCGCCGGTGCCCCCCGCTCGGCGGTGGAGCCGCTGGTGCTCATGCTGGCACCGTTGGCCCCGCACC
TCGCGGAGGAACTGTGGTCGCGGCTCGGCCACGAGAAGTCGCTGGCGCACGGCCCCTTCCCGGTTGCGGAGGAGAAGTGG
CTCGTCGAAGACACCGTCGAGTACCCGATCCAGGTCAACGGCAAGGTCCGCAGCCGCGTCACCGTCGCCGCCGACGCCCC
GCGTGAGGAGATCGAGAAGATCGCCCTTGCCGACGACAAGATCGTCGCACTGCTCGACGGCAAGGATCCGCGCAAGGTCA
TCGTCGTGCCGGGGAAGATGGTCAACATCGTCCTCTGA

Protein sequence :
MTEHVQPANPSDATPQHRYTAELAGQIEQRWQDRWSEEGTFDAPNPVGPLAGDVPADKLFVQDMFPYPSGTGLHVGHPLG
YIATDVFARYHRMQGHNVLHTLGYDAFGLPAEQYAVQTGTHPRTTTEANIGNMKRQLRRLGLGHDERRTFATTDVDFYHW
TQWIFLQIHDAWFDKEAGKARRISELEAEFVSGARALEDGRDWASLPATEKEAVLDSYRLVYHSDSMVNWCPGLGTVLAN
EEVTADGRSDRGNFPVFRKHLQQWMMRITAYSDRLVDDLEYLDWPEKVKTMQRNWIGRSHGAQVRFDANGHGIEVFTTRP
DTLFGATYVTLAPEHELVDEIVAAAWPEGVDARWTGGAATPGEAVAAYRKSIAAKSDLERQEYKEKTGVFLGTYAVNPVN
GHKLPVFIADYVLTGYGTGAIMAVPGHDHRDYEFATEFGLDIVEVISGGDLSKDAYTGDGTIVNSDFLNGMSVTDAKKAI
TDRLEADGTGKGTIQYKLRDWLFARQRYWGEPFPIVYDADGNAHALPESALPVELPEVEDYAPVSFDPDDASSEPSPPLA
KAVDWVNVELDLGDGLQTYRRDTNVMPQWAGSSWYQLRYIDPTNPDVFCDKENERYWTGPRPEIHGPNDPGGVDLYVGGV
EHAVLHLLYSRFWHKVLFDLGYVSSSEPYRRLYNQGYIQAYAYTDARGVYVPADEVEEKDGKFFHQGAEVNREYGKMGKS
LKNSVSPDDICEEYGADTLRVYEMSMGPLDTSRPWATKDVVGAQRFLQRAWRVVVDEESGAVRVTDDAPTEDTLRALNKA
IAGVGEDYTALRDNTAAAKLIEYTNHLTKAYPAGAPRSAVEPLVLMLAPLAPHLAEELWSRLGHEKSLAHGPFPVAEEKW
LVEDTVEYPIQVNGKVRSRVTVAADAPREEIEKIALADDKIVALLDGKDPRKVIVVPGKMVNIVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 9e-149 48