Gene Information

Name : pyk (ROP_26990)
Accession : YP_002779891.1
Strain : Rhodococcus opacus B4
Genome accession: NC_012522
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 2905367 - 2906845 bp
Length : 1479 bp
Strand : -
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGCCCACCATCGATATCGAACGGTCCGCAGCACACACCGCACAGCCCGGTCTGCTCAGCACGTCCCGGCGCACGAAGAT
CGTATGCACACTTGGACCTGCTACCGCCACCGGTGACCGTATTCGCGAGCTCGTCGAGAGCGGTATGGATGTGGCGCGGC
TGAATTTCAGCCACGGCGAGCACGCCGATCACGAGGAGAACTACAAACGTGTGAGGGCGGCCTCGGACGCGACGGGTAAG
GCGGTCGGTGTCCTGGCCGACCTGCAGGGGCCGAAGATCCGGTTGGGCCGGTTCGCGGAGGGGCGCACCACGTGGGCGAA
CGGTGAGGAGGTGCGGATCACCGTCGAGGAGTGTGAGGGCACCCACGACCGGGTCTCGACCACGTACAAGCAGCTGGCCG
AGGACGCCAAGCCGGGGGACCGGTTGCTGGTGGACGACGGCAAGGTCGGTCTGGTGGTCTCCGGGGTGGAGGGCAATGAC
GTGATCTGCCGGGTCACCGAGGGCGGCCCGGTGTCGAACAACAAGGGTGTGTCGCTGCCGGGGATGAATGTGTCGGTTCC
GGCGCTGTCGGAGAAGGACATCGCGGATCTGGAGTTCGCGCTCGGGTTGGGTGTCGATTTCATCGCGTTGTCGTTCGTGC
GGTCGCCGGCGGATGTGGAGTTGGTGCATGCGGTGATGGACCGGGTGGGTCGGCGGATTCCGGTGATCGCGAAGTTGGAG
AAGCCGGAGGCGATCGACAATCTCGAGGCGATCGTGCTGGCGTTCGATGCGGTGATGGTGGCGCGGGGTGATCTGGGTGT
GGAGTTGCCGCTCGAGCAGGTGCCGTTGGTGCAGAAGCGGGCGATTCAGATTGCGCGGGAGAACGCGAAGCCGGTGATCG
TGGCGACGCAGATGCTGGAGTCGATGATCGAGAACTCGCGGCCGACCCGGGCGGAGGCCTCGGATGTGGCGAACGCGGTC
CTCGACGGGGCGGATGCGGTGATGCTGTCCGGGGAGACGTCGGTGGGTAAGTACGTGATGGAGACGGTGCGCACGATGGC
GCGGATCGTGGAGGCGGTGGAGAACGAGTCCACGCAGGTGCCGCCGCTGACGCATGTGCCGCGGACCAAGCGGGGGGTGA
TCTCGTACGCGGCCCGCGACATCGGGGAGCGCCTGGATGCGAAGGCGTTGGTGGCGTTCACGCAGTCGGGGGACACGGTG
CGCCGGTTGGCGCGGTTGCATACGCCGTTGCCGTTGCTGGCGTTCACGCCGTTGCCGGAGGTGCGCAGCCAGTTGTCGTT
GACGTGGGGGACGGAGACGTTCACCGTCGACCCGGTCGACAGCACGGATGCGATGGTGCGGCAGGTCGACAACGCGCTGC
TCGGGTTGGGCCGGTACCAGAAGGGTGAACTCGTGGTGATCGTGGCGGGGTCGCCGCCGGGCACCGTAGGCTCGACCAAC
CTGATCCACGTCCACAGAATCGGCGAAGAAGACCACTAG

Protein sequence :
MPTIDIERSAAHTAQPGLLSTSRRTKIVCTLGPATATGDRIRELVESGMDVARLNFSHGEHADHEENYKRVRAASDATGK
AVGVLADLQGPKIRLGRFAEGRTTWANGEEVRITVEECEGTHDRVSTTYKQLAEDAKPGDRLLVDDGKVGLVVSGVEGND
VICRVTEGGPVSNNKGVSLPGMNVSVPALSEKDIADLEFALGLGVDFIALSFVRSPADVELVHAVMDRVGRRIPVIAKLE
KPEAIDNLEAIVLAFDAVMVARGDLGVELPLEQVPLVQKRAIQIARENAKPVIVATQMLESMIENSRPTRAEASDVANAV
LDGADAVMLSGETSVGKYVMETVRTMARIVEAVENESTQVPPLTHVPRTKRGVISYAARDIGERLDAKALVAFTQSGDTV
RRLARLHTPLPLLAFTPLPEVRSQLSLTWGTETFTVDPVDSTDAMVRQVDNALLGLGRYQKGELVVIVAGSPPGTVGSTN
LIHVHRIGEEDH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-66 41
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 3e-66 41
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-66 41
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-66 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_002779891.1 pyruvate kinase VFG0479 Protein 5e-67 41