Gene Information

Name : ROP_23290 (ROP_23290)
Accession : YP_002779521.1
Strain : Rhodococcus opacus B4
Genome accession: NC_012522
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : 6.3.2.-
Position : 2502513 - 2504120 bp
Length : 1608 bp
Strand : +
Note : -

DNA sequence : 
ATGAGCGAAAATACAGACCACCGAGTCGGTTTCGTTCCGTTCCCCGACGCCGACTCCGACCGATACCGGGCGTGCGGATA
CTGGCGGGGCGAACCACTCGGTGACATCCTGCGGCGTGCCGCGCACCGCTGGCCGCAACGCCCGGCCATCCTGGCCGACG
ACACGACCACCTACGCGCAACTCGATTCGGCGGCCGACCGGATGGCCTCGGGATTGATGCGGATGGGCTTCGCCCCCGGC
GACCGGGTCGTCGTCCAGCTCCCCAACGTTCCCGAATTCGCAGTGGTGTTCTTCGGGCTGCTCCGGGCCGCCGCCATCCC
CGTGCTGTGCCTGCCCGCACACCGCGAACGGGAGATCGGACACCTCGCCGCACTGTCGGGTGCGATCGGTTATGTGGTCG
CCGACCGCGTCGGCGGGTACGACTACCGCGAGCTGGCACGGGCCGTGCGCGCCGCCGCGCCGTCCGTCGAACACGTCCTC
GTGCACGGCGACGCCAGGGAATTCACCTCGCTGGCGTCGGTTCCCGCCACTGTTCGCGAGCTCCCCACCGTCGATCCGGC
CGACGTCGCGGTGCTGCTGATCTCCGGGGGGACGACCGGTGTTCCCAAACTCATCGCCCGCACACACGACGACTACGCGT
ACAACGCGCGGGCGAGCGCAGAGGTGTGCGCCCTGACCGGAGACGACGTCTACCTCGTCGCATTGCCTGCCGCACACAAC
TTCCCACTCGCCTGCCCCGGCATCCTCGGCACGTTCGGTGTCGGCGGCGCCGTGACGTTCCTCGCCGACCCGAGCCCCGA
GTCCGCATTCGCCGCCATCGAACGACACCGCGCCACCGTCACCGCCGTGGTGCCGCCGCTCGCGCAACTGTGGTGCACCG
CCACCGAATGGGAATCCGCCGATCCGGGTTCGCTGCGGCTGCTGCAGGTCGGCGGTGCGAAGCTGGCCGAGAACGCGGCC
CGTGAGGTCCGGCCGCGGCTGGGTGCCGCGCTGCAACAGGTGTTCGGGATGGCCGAGGGGCTGCTGAACTACACGCGGCT
CGACGACCCCGACGATCTGGTCGCGACCAGCCAGGGCCGGCCGCTGTCCGAACTGGACGAGGTCCGGATCGTCGACGACG
CCGGCAACGACGTCCCCGCCGGAACGGAGGGCGAGTTGCTCACACGCGGTCCCTACACGATCCGGGGGTACTACCGCGCC
GCCGAGCACAACGCCCGCGCCTTCACCGCCGACGGCTTCTACCGCAGTGGCGACCTGGTCCGCCGACTGCCGTCCGGTCA
CCTGGTCGTCACCGGCCGCATCAAGGACGTCATCAACCGGGGCGGCGAGAGCGTGTCCGCCGGCGAAGTGGAGGAGCACC
TGCTCGCGCATCCGGCCGTGGTCCAGGTCGCGGTGATCGGCCTGCCCGACGACGATCTGGGTGAACGAGTCTGTGCAGCA
ATGGTCGTCGACGACACCCTGCCCACCCTCGCGCAGCTCAAGGACTTTCTGACCGGACGCGGTCTGGCACCGTTCAAGCA
CCCCGACCTGCTCCACGTCGTCGAGCACCTGCCGGTCACGGCAGTCGGGAAGATCGACAAACGTGCGGTTGCCGCGGACA
TCGGATGA

Protein sequence : 
MSENTDHRVGFVPFPDADSDRYRACGYWRGEPLGDILRRAAHRWPQRPAILADDTTTYAQLDSAADRMASGLMRMGFAPG
DRVVVQLPNVPEFAVVFFGLLRAAAIPVLCLPAHREREIGHLAALSGAIGYVVADRVGGYDYRELARAVRAAAPSVEHVL
VHGDAREFTSLASVPATVRELPTVDPADVAVLLISGGTTGVPKLIARTHDDYAYNARASAEVCALTGDDVYLVALPAAHN
FPLACPGILGTFGVGGAVTFLADPSPESAFAAIERHRATVTAVVPPLAQLWCTATEWESADPGSLRLLQVGGAKLAENAA
REVRPRLGAALQQVFGMAEGLLNYTRLDDPDDLVATSQGRPLSELDEVRIVDDAGNDVPAGTEGELLTRGPYTIRGYYRA
AEHNARAFTADGFYRSGDLVRRLPSGHLVVTGRIKDVINRGGESVSAGEVEEHLLAHPAVVQVAVIGLPDDDLGERVCAA
MVVDDTLPTLAQLKDFLTGRGLAPFKHPDLLHVVEHLPVTAVGKIDKRAVAADIG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-106 49
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-106 49
ybtE CAA21394.1 - Virulence HPI Protein 3e-106 49
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 2e-106 49
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 3e-106 49
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-106 49
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 3e-106 49
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 1e-104 48
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-104 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ROP_23290 YP_002779521.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 7e-139 56
ROP_23290 YP_002779521.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 7e-103 49
ROP_23290 YP_002779521.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 2e-91 43