Gene Information

Name : thyA (ROP_19620)
Accession : YP_002779154.1
Strain : Rhodococcus opacus B4
Genome accession: NC_012522
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 2098267 - 2099070 bp
Length : 804 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
GTGACATCTGTGCCGACCCCGTACGAAGACCTGCTCCGACTCGTCATGGACACGGGCACCCCGAAGGCCGACCGCACCGG
GACCGGCACGAGGAGCGTCTTCGGTCATCAGATGCGCTGGAATCTCGCGGACGGGTTTCCGCTGGTCACCACGAAGAAGG
TGCATCTCAAGTCGATCGTCTACGAACTGTTGTGGTTCCTGCGCGGCGACTCCAACGTGAAGTGGCTCCAGGACAACGGC
GTCACGATCTGGGACGAATGGGCGGACGCGGACGGCGAACTGGGCCCGGTCTACGGCGTGCAGTGGCGGAGCTGGCCGAC
CCCGTCCGGCGAGCACATCGACCAGATCAGCCAGACCATCGAGACGCTGAAGTCGAACCCGGATTCGCGTCGCATCATCG
TGTCGGCGTGGAACGTCGGCGACATCCCGCAGATGGCGCTGGCACCGTGCCACGCGTTCTTCCAGTTCTACGTAGCGGAC
GGCAAGCTGTCCTGCCAGCTGTACCAGCGCAGCGCCGACATGTTCCTGGGTGTGCCGTTCAACATCGCGAGCTACGCCCT
CCTCACCCACATGGTGGCGCAGCAGGCGGGGCTCGAACCGGGCGACTTCATCTGGACAGGTGGTGACTGCCACATCTACG
ACAACCACGTCGACCAGGTCGCCGAGCAGTTGAGCCGGGAGCCGCTGCCGTATCCGACGCTGAAACTGAACAGGCGGGAT
TCGATCTTCGACTACACGTTCGAGGACGTGGAGATCGTCGACTACCGGCATCATCCCGCCATCAAGGCGCCGGTGGCCGT
CTAG

Protein sequence :
MTSVPTPYEDLLRLVMDTGTPKADRTGTGTRSVFGHQMRWNLADGFPLVTTKKVHLKSIVYELLWFLRGDSNVKWLQDNG
VTIWDEWADADGELGPVYGVQWRSWPTPSGEHIDQISQTIETLKSNPDSRRIIVSAWNVGDIPQMALAPCHAFFQFYVAD
GKLSCQLYQRSADMFLGVPFNIASYALLTHMVAQQAGLEPGDFIWTGGDCHIYDNHVDQVAEQLSREPLPYPTLKLNRRD
SIFDYTFEDVEIVDYRHHPAIKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 4e-96 72