Gene Information

Name : thiC (ROP_18970)
Accession : YP_002779089.1
Strain : Rhodococcus opacus B4
Genome accession: NC_012522
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 2011123 - 2012769 bp
Length : 1647 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAGCACAGACATATCTACAGCCACGTCCGTCACCACGGGACCGATCCAGGGCAGCACCAAGCAGTACCTGCAGTCGGG
CGACGACATCCGCGTCCCGGTCCGGCGCGTCGACCTCACCAACGGTGAGCACCTCGACGTGTACGACACGTCGGGTCCGT
ACACCGACGCGGACGCCACGATCGACCTCGACGCGGGGCTTCCGCATCTGCGTGCGCCGTGGATCGCCGACCGGGCAGAC
ACCCAGCTCGACGCCGCCCGTGCCGGAATCGTCACCCCCGAGATGCGGTATTGCGCTGCACGAGAGGGCGTTTCGCCTGA
GACAGTGCGCGTCGAGGTCGCGGCGGGTCGCGCCGTGATCCCGGCCAACCGCTGCCACCCCGAACTCGAGCCGATGATCA
TCGGCAAGGCGTTCGCGGTCAAGATCAACGCGAACATCGGCAACAGCGCGGTGACGTCGTCGATCGCGGAAGAGGTCGAG
AAGATGGTGTGGGCGACCCGGTGGGGCGCGGACACCATCATGGACCTCTCCACCGGCAAGAACATTCACGAGACCCGGGA
ATGGATCCTGCGCAATTCGCCGGTGCCCGTGGGGACGGTGCCGATTTATCAGGCGCTCGAGAAGGTGAACGGAGATCCGA
CGGCACTGACGTGGGAGATCTACCGCGACACCGTGATCGAGCAGTGCGAGCAGGGTGTCGACTACATGACGGTCCACGCC
GGGGTGCTGCTCCGCTACATCCCGCTGACCGCGAAACGCGTGACCGGCATCGTCTCGCGCGGCGGTTCGATCATGGCGGC
ATGGTGTCTGGCCCATCACCGGGAATCGTTCCTGTACACCCACTTCGACGAACTCTGCGAAATCCTCCACCGCTACGACG
TCACGTTCTCGCTCGGCGACGGACTCCGTCCCGGGTCCATCGCGGACGCCAACGACGAGGCCCAGTTCGCGGAACTCCGT
ACCCTCGGGAAGCTCACGAAGATCGCGAAATCGCATGGCGTGCAGGTGATGATCGAAGGTCCCGGGCACGTACCGATGCA
CAAGATCGTCGAGAACGTGCGGCTCGAGGAGGAGCTGTGCGAGGAGGCGCCGTTCTACACGCTCGGACCGCTCGCCACCG
ACATCGCACCGGCGTACGACCACATCACGTCCGCGATCGGGGCGGCGATGATCGCGCAGGCCGGCACCGCGATGCTCTGC
TACGTCACTCCCAAGGAGCACCTGGGGCTGCCGAACCGCGACGACGTCAAGATCGGCGTGATCACGTACAAGATCGCGGC
GCACGCCGCGGACCTCGCGAAGCAGCATCCGCGGGCGCAGGAACGGGACGACGCGCTGTCGAAGGCCCGGTTCGAGTTCC
GCTGGCACGACCAGTTCGCGCTGTCCCTCGACCCGGATACGGCGCGGGAGTTCCACGACGAAACCCTGCCCGCGGAGCCG
GCGAAGACGGCCCACTTCTGCTCGATGTGCGGCCCGAAGTTCTGTTCCATGCGGATCTCCGCCGATGTCCGCGAGTACGC
GCAGAAGCACGGCCTCGACTCCATCGAAGCCATCGAGGCGGGCATGGCCGAGAAGTCCAGCGAGTTCGTCGACGCAGGTG
GCCGCGTGTATCTGCCCCTCGAATCCGTCACCTCAGAGAATCGGTAA

Protein sequence :
MSTDISTATSVTTGPIQGSTKQYLQSGDDIRVPVRRVDLTNGEHLDVYDTSGPYTDADATIDLDAGLPHLRAPWIADRAD
TQLDAARAGIVTPEMRYCAAREGVSPETVRVEVAAGRAVIPANRCHPELEPMIIGKAFAVKINANIGNSAVTSSIAEEVE
KMVWATRWGADTIMDLSTGKNIHETREWILRNSPVPVGTVPIYQALEKVNGDPTALTWEIYRDTVIEQCEQGVDYMTVHA
GVLLRYIPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTHFDELCEILHRYDVTFSLGDGLRPGSIADANDEAQFAELR
TLGKLTKIAKSHGVQVMIEGPGHVPMHKIVENVRLEEELCEEAPFYTLGPLATDIAPAYDHITSAIGAAMIAQAGTAMLC
YVTPKEHLGLPNRDDVKIGVITYKIAAHAADLAKQHPRAQERDDALSKARFEFRWHDQFALSLDPDTAREFHDETLPAEP
AKTAHFCSMCGPKFCSMRISADVREYAQKHGLDSIEAIEAGMAEKSSEFVDAGGRVYLPLESVTSENR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 1e-164 62
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 1e-164 62
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 1e-158 60