Gene Information

Name : megL (BBR47_55420)
Accession : YP_002775023.1
Strain : Brevibacillus brevis NBRC 100599
Genome accession: NC_012491
Putative virulence/resistance : Resistance
Product : methionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.11
Position : 5857146 - 5858354 bp
Length : 1209 bp
Strand : -
Note : -

DNA sequence :
ATGACGACAAATAAGTGGAAGATGGACACCTCCATTATTCATACCGCACAAACGCCTTGCCAAAAAACAGGAGCAGTGGT
ATCCGCGGTGGTGCCTGCTGTGGCCTATGCGTTTCCAGATGCAGATTCCGCAGCGGCGTGCGTGGCTGGTGAGCGAGAAG
GAACGTACTACGGAAGATATGGCAATCCTACCATCAGCACTTTAGAGCAAAAAATCGCCGCATTGGAAAATGGTGAAGCT
GCCCTGGGCGTAAGCAGTGGGATGGCTGCCATATCGGGGGCTTTGCTCGCCTTTTTGAAGCAGGGTGATCATGTGGTGTG
TACGCGAGATGTGTACGGGGGGAGCTACAAGTTTCTTACGACCATGGCTCCGCGTTACGGCATTGCGACGGACTTCGTCG
ATTGCACCGATTTGGAGGCAGTCGAGAGTGCCTTTTTGCCGAACACAAAAGTCCTGTACATCGAAACACCCTCGAACCCG
TGCCTGACCGTTTTAGATATCTCGGCGCTGTCCCTATTGGCGCACGCTCATGGCATTGTGGTAATCGTCGACAACACCTT
CTTAACGCCGTATTTACAGCGACCACTTGAGCTAGGGGCAGATGTCGTCGTGCATAGCGCCACCAAATATTTGAACGGAC
ATGGCGATGTGATCGCGGGCTTTATCGTCGGGAAGCAGGAGCATATCCAATTCATGCGCAAAAACGTCATGGGTGACTTG
GGACAAAATTTGAATGCTTGGGATGCTTTTTTAATCCTGCGTGGGATGAAGACACTCGGCTTGCGTGTCAGACAGCATGG
ACAAAACGCTCAGGCAGTCGCGGAGTTTTTGGCGAAGCACCCTGCAATCTCCCACGTTTATTACCCTGGTCTGCCTTCGC
ATCCACAGCATGAGCTGGCTAAACGGCAAATGGCCGGAATGGGCGGGATCGTTTCTTTTGAAGTAAAGGGCGGTTACGAG
GCAGCCAAATCTTTCATTAACGCTCTGCACTTGGCTATGATATCGTTTAGTTTAGGAGATCCCGAGACACTGGTACAGCA
TCCTGCCTCGATGACGCATTCCTCGATCCCTGCTTCCGAGCGGATCAAGTTCAACATTACGGACGGTCTGATTCGCTTAT
CGACTGGTTTGGAGGACGTGGAGGATATCATCGCAGATTTGGAGCAGGCGCTAGCTAGCTTGCCCGTGGCGGCAGCGTCC
AGGGGATAA

Protein sequence :
MTTNKWKMDTSIIHTAQTPCQKTGAVVSAVVPAVAYAFPDADSAAACVAGEREGTYYGRYGNPTISTLEQKIAALENGEA
ALGVSSGMAAISGALLAFLKQGDHVVCTRDVYGGSYKFLTTMAPRYGIATDFVDCTDLEAVESAFLPNTKVLYIETPSNP
CLTVLDISALSLLAHAHGIVVIVDNTFLTPYLQRPLELGADVVVHSATKYLNGHGDVIAGFIVGKQEHIQFMRKNVMGDL
GQNLNAWDAFLILRGMKTLGLRVRQHGQNAQAVAEFLAKHPAISHVYYPGLPSHPQHELAKRQMAGMGGIVSFEVKGGYE
AAKSFINALHLAMISFSLGDPETLVQHPASMTHSSIPASERIKFNITDGLIRLSTGLEDVEDIIADLEQALASLPVAAAS
RG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-66 47
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-65 46
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-62 46

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
megL YP_002775023.1 methionine gamma-lyase BAC0207 Protein 4e-76 50