Gene Information

Name : metI (BBR47_38780)
Accession : YP_002773359.1
Strain : Brevibacillus brevis NBRC 100599
Genome accession: NC_012491
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase/O-acetylhomoserine aminocarboxypropyltransferase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 4060349 - 4061512 bp
Length : 1164 bp
Strand : -
Note : -

DNA sequence :
ATGAAATTGGAAACAAAGTTGATTCAGGCGGGAGTAGGCAAAGACGAAAAAACAGGGGCGGTGAGCTTTCCTGTTTACTA
TGCAACGGCTTATCGTCATCCTGCCTTGGGCCAGAGCACTGGATATGATTATACGCGCACAGCTAATCCTACTCGTACCA
TTTTGGAGGAGACCATCGCTATAGCGGAATCAGGAGATGCAGGATTCGCTTGCGCCTCGGGAATGGCTGCTGTTCATACC
GTCATGGGTTTGTTTTCCCAAGGAGATCATCTGATTGTTTCGCTCGATCTGTACGGGGGAACCTATCGATTGTTCGAGCA
AGTGCTCTCTCGTTACGGTCTGACGTTTTCGTACGTGGATTTGCGTGACATTGTTGCACTGAAAAATGCGATTTGCCCAG
ACACAAAGGCTATTTTCGTCGAGACACCAACCAATCCGCTCATGCAGATTACCGATATTCGAGCAGTAGCACAATTGGCG
AAGCAGCACAGTCTCCTGACGATTGTAGACAACACATTCTTAACCCCGTATTGTCAACGCCCACTAGAGCTTGGTGCAGA
TATCGTCTTACATAGTGCGACCAAGTATTTGGCAGGACACAACGATGTGTTGGCTGGACTCATCGTAACAAAAGGAGAAG
AGTTGTCGGAAAAAATCCGGTTTTTGCACAATTCAATCGGTGCTGTACTCGGACCTCAAGATTGCTGGCTTCTCATTCGC
GGGATGAAAACATTGGCATTGCGGATGGAGCGCCATCAATCCAATGCCTTGATTGTAGCGGAAAAGCTGCGTGAGCATCC
GGCAGTAGCGGAGGTATTTTATCCGGGTCTGCCAGAGCATCCGGGACATGAGATCCAGGTGAATCAAGCGACAGGGCATA
GTGGGATGGTTTCGTTCCGCGTACGCGATGTGGAGCAGGTGGGATTGTTCCTGCAAAATCTGCAAATCGTGTCCTTTGCT
GAAAGCCTGGGTGGTGTTGAGTCATTGTGTACGTATCCGGCGACGCAGACTCACGCGGATATCCCGCAAGAAGTCAGAGA
GCATGTCGGTGTTTGTTATCGATTGTTGCGGCTGTCGGTTGGCATCGAGCATCCAGATGATGTCGTAGCCGATTTGTTTC
AGGCCTTGAATGCTAGTTTGGTCGTAGGGGGGAGTGTACGATGA

Protein sequence :
MKLETKLIQAGVGKDEKTGAVSFPVYYATAYRHPALGQSTGYDYTRTANPTRTILEETIAIAESGDAGFACASGMAAVHT
VMGLFSQGDHLIVSLDLYGGTYRLFEQVLSRYGLTFSYVDLRDIVALKNAICPDTKAIFVETPTNPLMQITDIRAVAQLA
KQHSLLTIVDNTFLTPYCQRPLELGADIVLHSATKYLAGHNDVLAGLIVTKGEELSEKIRFLHNSIGAVLGPQDCWLLIR
GMKTLALRMERHQSNALIVAEKLREHPAVAEVFYPGLPEHPGHEIQVNQATGHSGMVSFRVRDVEQVGLFLQNLQIVSFA
ESLGGVESLCTYPATQTHADIPQEVREHVGVCYRLLRLSVGIEHPDDVVADLFQALNASLVVGGSVR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 7e-90 47
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-91 47
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 7e-65 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metI YP_002773359.1 cystathionine gamma-synthase/O-acetylhomoserine aminocarboxypropyltransferase BAC0207 Protein 1e-61 42